Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death
Aires, Virginie, Limagne, Emeric, Cotte, Alexia K., Latruffe, Norbert, Ghiringhelli, François, Delmas, Dominique
Published in Molecular nutrition & food research (01.07.2013)
Published in Molecular nutrition & food research (01.07.2013)
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Emergence of Lipid Droplets in the Mechanisms of Carcinogenesis and Therapeutic Responses
Delmas, Dominique, Cotte, Alexia K, Connat, Jean-Louis, Hermetet, François, Bouyer, Florence, Aires, Virginie
Published in Cancers (14.08.2023)
Published in Cancers (14.08.2023)
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Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis
Bobowski-Gerard, Marie, Boulet, Clémence, Zummo, Francesco P., Dubois-Chevalier, Julie, Gheeraert, Céline, Bou Saleh, Mohamed, Strub, Jean-Marc, Farce, Amaury, Ploton, Maheul, Guille, Loïc, Vandel, Jimmy, Bongiovanni, Antonino, Very, Ninon, Woitrain, Eloïse, Deprince, Audrey, Lalloyer, Fanny, Bauge, Eric, Ferri, Lise, Ntandja-Wandji, Line-Carolle, Cotte, Alexia K., Grangette, Corinne, Vallez, Emmanuelle, Cianférani, Sarah, Raverdy, Violeta, Caiazzo, Robert, Gnemmi, Viviane, Leteurtre, Emmanuelle, Pourcet, Benoit, Paumelle, Réjane, Ravnskjaer, Kim, Lassailly, Guillaume, Haas, Joel T., Mathurin, Philippe, Pattou, François, Dubuquoy, Laurent, Staels, Bart, Lefebvre, Philippe, Eeckhoute, Jérôme
Published in Nature communications (10.09.2022)
Published in Nature communications (10.09.2022)
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The ubiquitin-like modifier FAT10 is induced in MASLD and impairs the lipid-regulatory activity of PPARα
Clavreul, Ludivine, Bernard, Lucie, Cotte, Alexia K, Hennuyer, Nathalie, Bourouh, Cyril, Devos, Claire, Helleboid, Audrey, Haas, Joel T, Verrijken, An, Gheeraert, Céline, Derudas, Bruno, Guille, Loïc, Chevalier, Julie, Eeckhoute, Jérôme, Vallez, Emmanuelle, Dorchies, Emilie, Van Gaal, Luc, Lassailly, Guillaume, Francque, Sven, Staels, Bart, Paumelle, Réjane
Published in Metabolism, clinical and experimental (01.02.2024)
Published in Metabolism, clinical and experimental (01.02.2024)
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Journal Article
Importance of lipid microdomains, rafts, in absorption, delivery, and biological effects of resveratrol
Delmas, Dominique, Aires, Virginie, Colin, Didier J., Limagne, Emeric, Scagliarini, Alessandra, Cotte, Alexia K., Ghiringhelli, François
Published in Annals of the New York Academy of Sciences (01.07.2013)
Published in Annals of the New York Academy of Sciences (01.07.2013)
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Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance
Cotte, Alexia Karen, Aires, Virginie, Fredon, Maxime, Limagne, Emeric, Derangère, Valentin, Thibaudin, Marion, Humblin, Etienne, Scagliarini, Alessandra, de Barros, Jean-Paul Pais, Hillon, Patrick, Ghiringhelli, François, Delmas, Dominique
Published in Nature communications (22.01.2018)
Published in Nature communications (22.01.2018)
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Journal Article
Chrysin-Induced Regression of Angiogenesis via an Induction of DNA Damage Response and Oxidative Stress in In Vitro and In Vivo Models of Melanoma
Sassi, Aicha, Fredon, Maxime, Cotte, Alexia K, Fuselier, Camille, Schneider, Christophe, Martiny, Laurent, Monchaud, David, Chekir-Ghedira, Leila, Aires, Virginie, Delmas, Dominique
Published in Cells (Basel, Switzerland) (01.06.2023)
Published in Cells (Basel, Switzerland) (01.06.2023)
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Liver X receptor ligand cytotoxicity in colon cancer cells and not in normal colon epithelial cells depends on LXRβ subcellular localization
Courtaut, Flavie, Derangère, Valentin, Chevriaux, Angélique, Ladoire, Sylvain, Cotte, Alexia K, Arnould, Laurent, Boidot, Romain, Rialland, Mickaël, Ghiringhelli, François, Rébé, Cédric
Published in Oncotarget (29.09.2015)
Published in Oncotarget (29.09.2015)
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Journal Article
LPCAT2 controls chemoresistance in colorectal cancer
Cotte, Alexia Karen, Aires, Virginie, Ghiringhelli, François, Delmas, Dominique
Published in Molecular & cellular oncology (01.01.2018)
Published in Molecular & cellular oncology (01.01.2018)
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Journal Article
Potential role of oxidative DNA damage in the impact of PNPLA3 variant (rs 738409 C>G) in hepatocellular carcinoma risk
Limagne, Emeric, Cottet, Vanessa, Cotte, Alexia Karen, Hamza, Samia, Hillon, Patrick, Latruffe, Norbert, Delmas, Dominique
Published in Hepatology (Baltimore, Md.) (01.09.2014)
Published in Hepatology (Baltimore, Md.) (01.09.2014)
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Impact of different sequencing strategies of talazoparib and carboplatin combination upon efficacy and toxicity in BRCA-wild type and BRCA-mutant triple-negative breast cancer models
Beniey, Michele, Cotte, Alexia, Hubert, Audrey, Bechir, Nelly, Haque, Takrima, Tran-Thanh, Danh, Hassan, Saima Noor
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Sequential targeting of PARP with carboplatin inhibits primary tumour growth and distant metastasis in triple-negative breast cancer
Beniey, Michèle, Hubert, Audrey, Haque, Takrima, Cotte, Alexia Karen, Béchir, Nelly, Zhang, Xiaomeng, Tran-Thanh, Danh, Hassan, Saima
Published in British journal of cancer (11.05.2023)
Published in British journal of cancer (11.05.2023)
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Abstract 1066: Pre-clinical combination of a PARP inhibitor, talazoparib, and carboplatin in triple-negative breast cancer
Cotte, Alexia, Beniey, Michèle, Haque, Takrima, Béchir, Nelly, Hubert, Audrey, Diallo, Korotoum W., Tran-Thanh, Danh, Hassan, Saima N.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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The ubiquitin-like modifier FAT10 is upregulated during NASH and impairs PPAR-alpha activity
Clavreul, Ludivine, Cotte, Alexia, Bernard, Lucie, Haas, Joel, Hennuyer, Nathalie, Verrijken, An, Van Gaal, Luc, Francque, Sven, Lassailly, Guillaume, Staels, Bart, Paumelle, Réjane
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
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Journal Article
CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway
Deleye, Yann, Cotte, Alexia Karen, Hannou, Sarah Anissa, Hennuyer, Nathalie, Bernard, Lucie, Derudas, Bruno, Caron, Sandrine, Legry, Vanessa, Vallez, Emmanuelle, Dorchies, Emilie, Martin, Nathalie, Lancel, Steve, Annicotte, Jean Sébastien, Bantubungi, Kadiombo, Pourtier, Albin, Raverdy, Violeta, Pattou, François, Lefebvre, Philippe, Abbadie, Corinne, Staels, Bart, Haas, Joel T., Paumelle, Réjane
Published in The Journal of biological chemistry (11.12.2020)
Published in The Journal of biological chemistry (11.12.2020)
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Phospholipid profiles and hepatocellular carcinoma risk and prognosis in cirrhotic patients
Cotte, Alexia Karen, Cottet, Vanessa, Aires, Virginie, Mouillot, Thomas, Rizk, Maud, Vinault, Sandrine, Binquet, Christine, de Barros, Jean-Paul Pais, Hillon, Patrick, Delmas, Dominique
Published in Oncotarget (15.03.2019)
Published in Oncotarget (15.03.2019)
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Abstract 5342: Identifying therapeutic targets in combination with PARP inhibitors using a 63-gene signature in triple-negative breast cancer
Hubert, Audrey, Cotte, Alexia, Bechir, Nelly, Haque, Takrima, Hassan, Saima N.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway
Deleye, Yann, Karen Cotte, Alexia, Hannou, Sarah Anissa, Hennuyer, Nathalie, Bernard, Lucie, Derudas, Bruno, Caron, Sandrine, Legry, Vanessa, Vallez, Emmanuelle, Dorchies, Emilie, Martin, Nathalie, Lancel, Steve S., Annicotte, Jean Sébastien, Bantubungi, Kadiombo, Pourtier, Albin, Raverdy, Violeta, Pattou, François, Lefebvre, Philippe, Abbadie, Corinne, Staels, Bart, Haas, Joel T, Paumelle, Réjane
Published in The Journal of biological chemistry (13.01.2021)
Published in The Journal of biological chemistry (13.01.2021)
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Journal Article
CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway
Deleye, Yann, Cotte, Alexia Karen, Hannou, Sarah Anissa, Hennuyer, Nathalie, Bernard, Lucie, Derudas, Bruno, Caron, Sandrine, Legry, Vanessa, Vallez, Emmanuelle, Dorchies, Emilie, Martin, Nathalie, Lancel, Steve, Annicotte, Jean Sébastien, Bantubungi, Kadiombo, Pourtier, Albin, Raverdy, Violeta, Pattou, François, Lefebvre, Philippe, Abbadie, Corinne, Staels, Bart, Haas, Joel T, Paumelle, Réjane
Published in The Journal of biological chemistry (11.12.2020)
Published in The Journal of biological chemistry (11.12.2020)
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