Preparative Scale Production of Recombinant Human Transthyretin for Biophysical Studies of Protein-Ligand and Protein-Protein Interactions
Cotrina, Ellen Y, Vilà, Marta, Nieto, Joan, Arsequell, Gemma, Planas, Antoni
Published in International journal of molecular sciences (17.12.2020)
Published in International journal of molecular sciences (17.12.2020)
Get full text
Journal Article
Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer
Cotrina, Ellen Y, Oliveira, Ângela, Leite, José Pedro, Llop, Jordi, Gales, Luis, Quintana, Jordi, Cardoso, Isabel, Arsequell, Gemma
Published in International journal of molecular sciences (01.10.2020)
Published in International journal of molecular sciences (01.10.2020)
Get full text
Journal Article
Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD
Rios, Xabier, Gómez-Vallejo, Vanessa, Martín, Abraham, Cossío, Unai, Morcillo, Miguel Ángel, Alemi, Mobina, Cardoso, Isabel, Quintana, Jordi, Jiménez-Barbero, Jesús, Cotrina, Ellen Y., Valencia, Gregorio, Arsequell, Gemma, Llop, Jordi
Published in Scientific reports (20.09.2019)
Published in Scientific reports (20.09.2019)
Get full text
Journal Article
Modulation of the Fibrillogenesis Inhibition Properties of Two Transthyretin Ligands by Halogenation
Cotrina, Ellen Y, Pinto, Marta, Bosch, Lluís, Vilà, Marta, Blasi, Daniel, Quintana, Jordi, Centeno, Nuria B, Arsequell, Gemma, Planas, Antoni, Valencia, Gregorio
Published in Journal of medicinal chemistry (27.11.2013)
Published in Journal of medicinal chemistry (27.11.2013)
Get full text
Journal Article
Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, Aβ Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer’s Disease Drug Discovery
Cotrina, Ellen Y, Gimeno, Ana, Llop, Jordi, Jiménez-Barbero, Jesús, Quintana, Jordi, Valencia, Gregorio, Cardoso, Isabel, Prohens, Rafel, Arsequell, Gemma
Published in Journal of medicinal chemistry (26.03.2020)
Published in Journal of medicinal chemistry (26.03.2020)
Get full text
Journal Article
Binding of common organic UV-filters to the thyroid hormone transport protein transthyretin using in vitro and in silico studies: Potential implications in health
Cotrina, Ellen Y., Oliveira, Ângela, Llop, Jordi, Quintana, Jordi, Biarnés, Xevi, Cardoso, Isabel, Díaz-Cruz, M. Silvia, Arsequell, Gemma
Published in Environmental research (15.01.2023)
Published in Environmental research (15.01.2023)
Get full text
Journal Article
Optimization of kinetic stabilizers of tetrameric transthyretin: A prospective ligand efficiency-guided approach
Cotrina, Ellen Y., Blasi, Daniel, Vilà, Marta, Planas, Antoni, Abad-Zapatero, Cele, Centeno, Nuria B., Quintana, Jordi, Arsequell, Gemma
Published in Bioorganic & medicinal chemistry (01.12.2020)
Published in Bioorganic & medicinal chemistry (01.12.2020)
Get full text
Journal Article
Targeting transthyretin in Alzheimer's disease: Drug discovery of small-molecule chaperones as disease-modifying drug candidates for Alzheimer's disease
Cotrina, Ellen Y., Santos, Luis Miguel, Rivas, Josep, Blasi, Daniel, Leite, José Pedro, Liz, Márcia A., Busquets, Maria Antònia, Planas, Antoni, Prohens, Rafel, Gimeno, Ana, Jiménez-Barbero, Jesús, Gales, Luis, Llop, Jordi, Quintana, Jordi, Cardoso, Isabel, Arsequell, Gemma
Published in European journal of medicinal chemistry (15.12.2021)
Published in European journal of medicinal chemistry (15.12.2021)
Get full text
Journal Article
Insights on the Interaction between Transthyretin and Aβ in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal
Gimeno, Ana, Santos, Luis M, Alemi, Mobina, Rivas, Josep, Blasi, Daniel, Cotrina, Ellen Y, Llop, Jordi, Valencia, Gregorio, Cardoso, Isabel, Quintana, Jordi, Arsequell, Gemma, Jiménez-Barbero, Jesús
Published in Journal of medicinal chemistry (13.07.2017)
Published in Journal of medicinal chemistry (13.07.2017)
Get full text
Journal Article
An Assay for Screening Potential Drug Candidates for Alzheimer's Disease That Act as Chaperones of the Transthyretin and Amyloid‐β Peptides Interaction
Cotrina, Ellen Y., Gimeno, Ana, Llop, Jordi, Jiménez‐Barbero, Jesús, Quintana, Jordi, Prohens, Rafel, Cardoso, Isabel, Arsequell, Gemma
Published in Chemistry : a European journal (23.12.2020)
Published in Chemistry : a European journal (23.12.2020)
Get full text
Journal Article
Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-β Formation in a Transgenic Mouse Model of Alzheimer's Disease: A Longitudinal in vivo Molecular Imaging Study1
Rejc, Luka, Gómez-Vallejo, Vanessa, Rios, Xabier, Cossío, Unai, Baz, Zuriñe, Mujica, Edurne, Gião, Tiago, Cotrina, Ellen Y, Jiménez-Barbero, Jesús, Quintana, Jordi, Arsequell, Gemma, Cardoso, Isabel, Llop, Jordi
Published in Journal of Alzheimer's disease (2020)
Published in Journal of Alzheimer's disease (2020)
Get more information
Journal Article