Pathway involving the N155H mutation in HIV-1 integrase leads to dolutegravir resistance
Malet, Isabelle, Ambrosio, Francesca A, Subra, Frédéric, Herrmann, Béatrice, Leh, Hervé, Bouger, Marie-Christine, Artese, Anna, Katlama, Christine, Talarico, Carmine, Romeo, Isabella, Alcaro, Stefano, Costa, Giosuè, Deprez, Eric, Calvez, Vincent, Marcelin, Anne-Geneviève, Delelis, Olivier
Published in Journal of antimicrobial chemotherapy (01.05.2018)
Published in Journal of antimicrobial chemotherapy (01.05.2018)
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Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β‐Amyloid Toxicity
Santoro, Anna Maria, Lanza, Valeria, Bellia, Francesco, Sbardella, Diego, Tundo, Grazia R., Cannizzo, Alessandra, Grasso, Giuseppe, Arizzi, Mariaconcetta, Nicoletti, Vincenzo G., Alcaro, Stefano, Costa, Giosuè, Pietropaolo, Adriana, Malgieri, Gaetano, D'Abrosca, Gianluca, Fattorusso, Roberto, García‐Viñuales, Sara, Ahmed, Ikhlas M. M., Coletta, Massimiliano, Milardi, Danilo
Published in ChemMedChem (05.02.2020)
Published in ChemMedChem (05.02.2020)
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New raltegravir resistance pathways induce broad cross-resistance to all currently used integrase inhibitors
Malet, Isabelle, Gimferrer Arriaga, Laura, Artese, Anna, Costa, Giosuè, Parrotta, Lucia, Alcaro, Stefano, Delelis, Olivier, Tmeizeh, Ahmed, Katlama, Christine, Valantin, Marc-Antoine, Ceccherini-Silberstein, Francesca, Calvez, Vincent, Marcelin, Anne-Geneviève
Published in Journal of antimicrobial chemotherapy (01.08.2014)
Published in Journal of antimicrobial chemotherapy (01.08.2014)
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Exploring new chemical functionalities to improve aromatase inhibition of steroids
Varela, Carla L., Amaral, Cristina, Correia-da-Silva, Georgina, Costa, Saul C., Carvalho, Rui A., Costa, Giosuè, Alcaro, Stefano, Teixeira, Natércia A.A., Tavares-da-Silva, Elisiário J., Roleira, Fernanda M.F.
Published in Bioorganic & medicinal chemistry (15.06.2016)
Published in Bioorganic & medicinal chemistry (15.06.2016)
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Inhibition of Human Monoamine Oxidase: Biological and Molecular Modeling Studies on Selected Natural Flavonoids
Carradori, Simone, Gidaro, Maria Concetta, Petzer, Anél, Costa, Giosuè, Guglielmi, Paolo, Chimenti, Paola, Alcaro, Stefano, Petzer, Jacobus P
Published in Journal of agricultural and food chemistry (30.11.2016)
Published in Journal of agricultural and food chemistry (30.11.2016)
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From Homology Modeling to the Hit Identification and Drug Repurposing: A Structure-Based Approach in the Discovery of Novel Potential Anti-Obesity Compounds
Costa, Giosuè, Artese, Anna, Ortuso, Francesco, Alcaro, Stefano
Published in Methods in molecular biology (Clifton, N.J.) (2021)
Published in Methods in molecular biology (Clifton, N.J.) (2021)
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ABCC Transporters Mediate the Vacuolar Accumulation of Crocins in Saffron Stigmas
Demurtas, Olivia Costantina, de Brito Francisco, Rita, Diretto, Gianfranco, Ferrante, Paola, Frusciante, Sarah, Pietrella, Marco, Aprea, Giuseppe, Borghi, Lorenzo, Feeney, Mistianne, Frigerio, Lorenzo, Coricello, Adriana, Costa, Giosuè, Alcaro, Stefano, Martinoia, Enrico, Giuliano, Giovanni
Published in The Plant cell (01.11.2019)
Published in The Plant cell (01.11.2019)
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Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses
Artese, Anna, Svicher, Valentina, Costa, Giosuè, Salpini, Romina, Di Maio, Velia Chiara, Alkhatib, Mohammad, Ambrosio, Francesca Alessandra, Santoro, Maria Mercedes, Assaraf, Yehuda G., Alcaro, Stefano, Ceccherini-Silberstein, Francesca
Published in Drug resistance updates (01.12.2020)
Published in Drug resistance updates (01.12.2020)
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Targeting SARS-CoV‑2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach
Ambrosio, Francesca Alessandra, Costa, Giosuè, Romeo, Isabella, Esposito, Francesca, Alkhatib, Mohammad, Salpini, Romina, Svicher, Valentina, Corona, Angela, Malune, Paolo, Tramontano, Enzo, Ceccherini-Silberstein, Francesca, Alcaro, Stefano, Artese, Anna
Published in Journal of chemical information and modeling (12.06.2023)
Published in Journal of chemical information and modeling (12.06.2023)
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Kaempferol as Selective Human MAO‑A Inhibitor: Analytical Detection in Calabrian Red Wines, Biological and Molecular Modeling Studies
Gidaro, Maria Concetta, Astorino, Christian, Petzer, Anél, Carradori, Simone, Alcaro, Francesca, Costa, Giosuè, Artese, Anna, Rafele, Giancarlo, Russo, Francesco M, Petzer, Jacobus P, Alcaro, Stefano
Published in Journal of agricultural and food chemistry (17.02.2016)
Published in Journal of agricultural and food chemistry (17.02.2016)
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Identification of Compounds Targeting HuD. Another Brick in the Wall of Neurodegenerative Disease Treatment
Ambrosio, Francesca Alessandra, Coricello, Adriana, Costa, Giosuè, Lupia, Antonio, Micaelli, Mariachiara, Marchesi, Nicoletta, Sala, Federico, Pascale, Alessia, Rossi, Daniela, Vasile, Francesca, Alcaro, Stefano, Collina, Simona
Published in Journal of medicinal chemistry (22.07.2021)
Published in Journal of medicinal chemistry (22.07.2021)
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Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome
Bagetta, Donatella, Maruca, Annalisa, Lupia, Antonio, Mesiti, Francesco, Catalano, Raffaella, Romeo, Isabella, Moraca, Federica, Ambrosio, Francesca Alessandra, Costa, Giosuè, Artese, Anna, Ortuso, Francesco, Alcaro, Stefano, Rocca, Roberta
Published in European journal of medicinal chemistry (15.01.2020)
Published in European journal of medicinal chemistry (15.01.2020)
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Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics
Rocca, Roberta, Palazzesi, Ferruccio, Amato, Jussara, Costa, Giosuè, Ortuso, Francesco, Pagano, Bruno, Randazzo, Antonio, Novellino, Ettore, Alcaro, Stefano, Moraca, Federica, Artese, Anna
Published in Scientific reports (21.02.2020)
Published in Scientific reports (21.02.2020)
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Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity
Dichiara, Maria, Ambrosio, Francesca Alessandra, Lee, Sang Min, Ruiz-Cantero, M. Carmen, Lombino, Jessica, Coricello, Adriana, Costa, Giosuè, Shah, Dhara, Costanzo, Giuliana, Pasquinucci, Lorella, Son, Kyung No, Cosentino, Giuseppe, González-Cano, Rafael, Marrazzo, Agostino, Aakalu, Vinay Kumar, Cobos, Enrique J., Alcaro, Stefano, Amata, Emanuele
Published in Journal of medicinal chemistry (24.08.2023)
Published in Journal of medicinal chemistry (24.08.2023)
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In Silico-Guided Rational Drug Design and Synthesis of Novel 4‑(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists
Romeo, Isabella, Brizzi, Antonella, Pessina, Federica, Ambrosio, Francesca Alessandra, Aiello, Francesca, Belardo, Carmela, Carullo, Gabriele, Costa, Giosuè, De Petrocellis, Luciano, Frosini, Maria, Luongo, Livio, Maramai, Samuele, Paolino, Marco, Moriello, Aniello Schiano, Mugnaini, Claudia, Scorzelli, Francesco, Maione, Sabatino, Corelli, Federico, Di Marzo, Vincenzo, Alcaro, Stefano, Artese, Anna
Published in Journal of medicinal chemistry (25.05.2023)
Published in Journal of medicinal chemistry (25.05.2023)
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Natural Agents as Novel Potential Source of Proteasome Inhibitors with Anti-Tumor Activity: Focus on Multiple Myeloma
Ambrosio, Francesca Alessandra, Costa, Giosuè, Gallo Cantafio, Maria Eugenia, Torcasio, Roberta, Trapasso, Francesco, Alcaro, Stefano, Viglietto, Giuseppe, Amodio, Nicola
Published in Molecules (Basel, Switzerland) (01.02.2023)
Published in Molecules (Basel, Switzerland) (01.02.2023)
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Identification and Characterization of New DNA G‑Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches
Alcaro, Stefano, Musetti, Caterina, Distinto, Simona, Casatti, Margherita, Zagotto, Giuseppe, Artese, Anna, Parrotta, Lucia, Moraca, Federica, Costa, Giosuè, Ortuso, Francesco, Maccioni, Elias, Sissi, Claudia
Published in Journal of medicinal chemistry (14.02.2013)
Published in Journal of medicinal chemistry (14.02.2013)
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The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile
Maruca, Annalisa, Catalano, Raffaella, Bagetta, Donatella, Mesiti, Francesco, Ambrosio, Francesca Alessandra, Romeo, Isabella, Moraca, Federica, Rocca, Roberta, Ortuso, Francesco, Artese, Anna, Costa, Giosuè, Alcaro, Stefano, Lupia, Antonio
Published in European journal of medicinal chemistry (01.11.2019)
Published in European journal of medicinal chemistry (01.11.2019)
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Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach
Romeo, Isabella, Ambrosio, Francesca Alessandra, Costa, Giosuè, Corona, Angela, Alkhatib, Mohammad, Salpini, Romina, Lemme, Saverio, Vergni, Davide, Svicher, Valentina, Santoro, Maria Mercedes, Tramontano, Enzo, Ceccherini-Silberstein, Francesca, Artese, Anna, Alcaro, Stefano
Published in Molecules (Basel, Switzerland) (01.11.2022)
Published in Molecules (Basel, Switzerland) (01.11.2022)
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