Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform
Long, Thomas J, Cosgrove, Patrick A, Dunn, 2nd, Robert T, Stolz, Donna B, Hamadeh, Hisham, Afshari, Cynthia, McBride, Helen, Griffith, Linda G
Published in Drug metabolism and disposition (01.12.2016)
Published in Drug metabolism and disposition (01.12.2016)
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Evolution of core archetypal phenotypes in progressive high grade serous ovarian cancer
Nath, Aritro, Cosgrove, Patrick A., Mirsafian, Hoda, Christie, Elizabeth L., Pflieger, Lance, Copeland, Benjamin, Majumdar, Sumana, Cristea, Mihaela C., Han, Ernest S., Lee, Stephen J., Wang, Edward W., Fereday, Sian, Traficante, Nadia, Salgia, Ravi, Werner, Theresa, Cohen, Adam L., Moos, Philip, Chang, Jeffrey T., Bowtell, David D. L., Bild, Andrea H.
Published in Nature communications (24.05.2021)
Published in Nature communications (24.05.2021)
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ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer
Farmaki, Elena, Nath, Aritro, Emond, Rena, Karimi, Kimya L, Grolmusz, Vince K, Cosgrove, Patrick A, Bild, Andrea H
Published in eLife (29.09.2023)
Published in eLife (29.09.2023)
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Exploiting collateral sensitivity controls growth of mixed culture of sensitive and resistant cells and decreases selection for resistant cells in a cell line model
Grolmusz, Vince Kornél, Chen, Jinfeng, Emond, Rena, Cosgrove, Patrick A, Pflieger, Lance, Nath, Aritro, Moos, Philip J, Bild, Andrea H
Published in Cancer cell international (17.06.2020)
Published in Cancer cell international (17.06.2020)
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A `one-two punch' therapy strategy to target chemoresistance in estrogen receptor positive breast cancer
Chi, Feng, Liu, Jiayi, Brady, Samuel W., Cosgrove, Patrick A., Nath, Aritro, McQuerry, Jasmine A., Majumdar, Sumana, Moos, Philip J., Chang, Jeffrey T., Kahn, Michael, Bild, Andrea H.
Published in Translational oncology (01.01.2021)
Published in Translational oncology (01.01.2021)
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Predicting clinical response to everolimus in ER+ breast cancers using machine-learning
Nath, Aritro, Cosgrove, Patrick A., Chang, Jeffrey T., Bild, Andrea H.
Published in Frontiers in molecular biosciences (11.10.2022)
Published in Frontiers in molecular biosciences (11.10.2022)
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Circulating immune cell phenotype dynamics reflect the strength of tumor–immune cell interactions in patients during immunotherapy
Griffiths, Jason I., Wallet, Pierre, Pflieger, Lance T., Stenehjem, David, Liu, Xuan, Cosgrove, Patrick A., Leggett, Neena A., McQuerry, Jasmine A., Shrestha, Gajendra, Rossetti, Maura, Sunga, Gemalene, Moos, Philip J., Adler, Frederick R., Chang, Jeffrey T., Sharma, Sunil, Bild, Andrea H.
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.2020)
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RAGE Inhibitors as Alternatives to Dexamethasone for Managing Cerebral Edema Following Brain Tumor Surgery
Liu, Shunan, Song, Yanyan, Zhang, Ian Y., Zhang, Leying, Gao, Hang, Su, Yanping, Yang, Yihang, Yin, Shi, Zheng, Yawen, Ren, Lyuzhi, Yin, Hongwei Holly, Pillai, Raju, Nath, Aritro, Medina, Eric F., Cosgrove, Patrick A., Bild, Andrea H., Badie, Behnam
Published in Neurotherapeutics (01.03.2022)
Published in Neurotherapeutics (01.03.2022)
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Serial single-cell genomics reveals convergent subclonal evolution of resistance as early-stage breast cancer patients progress on endocrine plus CDK4/6 therapy
Griffiths, Jason I, Chen, Jinfeng, Cosgrove, Patrick A, O'Dea, Anne, Sharma, Priyanka, Ma, Cynthia, Trivedi, Meghna, Kalinsky, Kevin, Wisinski, Kari B, O'Regan, Ruth, Makhoul, Issam, Spring, Laura M, Bardia, Aditya, Adler, Frederick R, Cohen, Adam L, Chang, Jeffrey T, Khan, Qamar J, Bild, Andrea H
Published in Nature cancer (01.06.2021)
Published in Nature cancer (01.06.2021)
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A mutation in Ampd2 is associated with nephrotic syndrome and hypercholesterolemia in mice
Helmering, Joan, Juan, Todd, Li, Chi Ming, Chhoa, Mark, Baron, Will, Gyuris, Tibor, Richards, William G, Turk, James R, Lawrence, Jeff, Cosgrove, Patrick A, Busby, Jim, Kim, Ki Won, Kaufman, Stephen A, Cummings, Connie, Carlson, George, Véniant, Murielle M, Lloyd, David J
Published in Lipids in health and disease (31.10.2014)
Published in Lipids in health and disease (31.10.2014)
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Abstract 388: Acquired sensitivity to ONC201/TIC10 in ER+ breast cancer progressing on the mTOR inhibitor everolimus
Farmaki, Eleni, Emond, Rena, Nath, Aritro, Grolmusz, Vince K., Cosgrove, Patrick A., Bild, Andrea H.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 6236: Systems biology modeling identifies SMARCD3 as a master regulator facilitating everolimus resistance in ER+ breast cancer
Medina, Eric F., Cosgrove, Patrick A., Farmaki, Eleni, Grolmusz, Vince K., Chi, Feng, Griffiths, Jason I., Bild, Andrea H., Nath, Aritro
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract 5693: Cancer cells subvert fibroblast function to promote a growth factor enriched tumor microenvironment in endocrine therapy resistant ER+ breast cancer
Griffiths, Jason I., Cosgrove, Patrick A., Castaneda, Eric Medina, Nath, Aritro, Chen, Jinfeng, Adler, Frederick R., Chang, Jeffrey T., Khan, Qamar J., Bild, Andrea H.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 4318: Cancer cell communication with macrophages prevents T cell activation during emergence of cell cycle therapy resistance
Griffiths, Jason I., Cosgrove, Patrick A., Castaneda, Eric Medina, Nath, Aritro, Chen, Jinfeng, Adler, Frederick R., Chang, Jeffrey T., Khan, Qamar J., Bild, Andrea H.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Cancer cells communicate with macrophages to prevent T cell activation during development of cell cycle therapy resistance
Griffiths, Jason I, Cosgrove, Patrick A, Eric Medina Castaneda, Nath, Aritro, Chen, Jinfeng, Adler, Frederick R, Chang, Jeffrey T, Khan, Qamar J, Bild, Andrea H
Published in bioRxiv (17.09.2022)
Published in bioRxiv (17.09.2022)
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Paper
Systems & Methods for Variant Payloads in Augmented Reality Displays
VACHON, Guy Craig, COSGROVE, Patrick A, MARTIN, Timothy S, MACAULEY, Robert M
Year of Publication 27.06.2019
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Year of Publication 27.06.2019
Patent
Exploiting collateral sensitivity controls growth of mixed culture of sensitive and resistant cells and decreases selection for resistant cells
Vince Kornel Grolmusz, Chen, Jinfeng, Emond, Rena, Cosgrove, Patrick A, Pflieger, Lance, Nath, Aritro, Moos, Philip J, Bild, Andrea H
Published in bioRxiv (08.05.2020)
Published in bioRxiv (08.05.2020)
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Paper
Tessellation and Connection System for Space Assembly of Modular Units
WONG, I.O.K. M, MIKHOPADHYAY, ROUNAK, COOPER, JOHN R, WALTZ, WALTER J, WHITE, BRACE W, DORSEY, JOHN T, SHEAFFER, DAMON E, ALLEN, B.DANETTE, PADDOCK, DAVID A, SONG, KYONGCHAN, KANG, DAVID, PLANT, JAMES V, DOGGETT, William R, WILLIAMS, RALPH A, COSGROVE, PATRICK A, CLINE, JULIA E, MARTIN, ROBERT F, VAUGHAN, MATTHEW P, TETER, JR., JOHN E, SHAZLY, SHERIF A
Year of Publication 31.03.2022
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Year of Publication 31.03.2022
Patent
A 'one-two punch' therapy strategy to target chemoresistance in ER+ breast cancer
Feng, Chi, Liu, Jiayi, Brady, Samuel W, Cosgrove, Patrick A, Nath, Aritro, Mcquerry, Jasmine A, Majumdar, Sumana, Moos, Philip J, Chang, Jeffrey T, Kahn, Michael, Bild, Andrea H
Published in bioRxiv (13.03.2020)
Published in bioRxiv (13.03.2020)
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Paper