LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity
Bonday, Zahid Q., Cortez, Guillermo S., Grogan, Michael J., Antonysamy, Stephen, Weichert, Ken, Bocchinfuso, Wayne P., Li, Fengling, Kennedy, Steven, Li, Binghui, Mader, Mary M., Arrowsmith, Cheryl H., Brown, Peter J., Eram, Mohammad S., Szewczyk, Magdalena M., Barsyte-Lovejoy, Dalia, Vedadi, Masoud, Guccione, Ernesto, Campbell, Robert M.
Published in ACS medicinal chemistry letters (12.07.2018)
Published in ACS medicinal chemistry letters (12.07.2018)
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Journal Article
Discovery of dual positive allosteric modulators (PAMs) of the metabotropic glutamate 2 receptor and CysLT1 antagonists for treating migraine headache
Blanco, Maria-Jesus, Benesh, Dana R., Knobelsdorf, James A., Khilevich, Albert, Cortez, Guillermo S., Mokube, Fese, Aicher, Thomas D., Groendyke, Todd M., Marmsater, Fredrik P., Tang, Tony P., Johnson, Kirk W., Clemens-Smith, Amy, Muhlhauser, Mark A., Swanson, Steven, Catlow, John, Emkey, Renee, Johnson, Michael P., Schkeryantz, Jeffrey M.
Published in Bioorganic & medicinal chemistry letters (15.01.2017)
Published in Bioorganic & medicinal chemistry letters (15.01.2017)
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Journal Article
A β-Lactone Route to Chiral γ-Substituted α-Amino Acids: Application to the Concise Synthesis of (S)-α-Azidobutyro Lactone and a Natural Amino Acid
Tennyson, Reginald L, Cortez, Guillermo S, Galicia, Héctor J, Kreiman, Charles R, Thompson, Christina M, Romo, Daniel
Published in Organic letters (21.02.2002)
Published in Organic letters (21.02.2002)
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Journal Article
ERK [23-c]-4- THIENO[23-C]PYRROL-4-ONE DERIVATIVES AS ERK INHIBITORS
JOSEPH SAJAN, MCMILLEN WILLIAM T, ZHAO GAIYING, CORTEZ GUILLERMO S, MCLEAN JOHNATHAN ALEXANDER, RODRIGUEZ MICHAEL JOHN
Year of Publication 17.07.2017
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Year of Publication 17.07.2017
Patent
5'-치환된 뉴클레오시드 유사체
DAHNKE KARL ROBERT, GROGAN MICHAEL JOHN, HERGUETA ANTONIO RODRIGUEZ, WATSON BRIAN MORGAN, CORTEZ GUILLERMO S, JAMISON JAMES ANDREW, BONDAY ZAHID QUYOOM, WOODS TIMOTHY ANDREW
Year of Publication 04.12.2017
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Year of Publication 04.12.2017
Patent
Total Synthesis of Lankacyclinol Generous financial support for this research was provided by the National Institutes of Health (Award no.: GM41560). Additionally, a National Institutes of Health Minority Predoctoral Fellowship (Award no.: GM18547) to G.S.C. is gratefully acknowledged. We also wish to thank Dr. Tsuneaki Hida and Dr. Yoshio Kozai, Takeda Chemical Ltd. (Japan), for providing us with an authentic sample of lankacyclinol as well as copies of the original (1)H NMR spectrum
Williams, David R., Cortez, Guillermo S., Bogen, Stéphane L., Rojas, Christian M.
Published in Angewandte Chemie International Edition (15.12.2000)
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Published in Angewandte Chemie International Edition (15.12.2000)
Journal Article
Total Synthesis of Lankacyclinol
Williams, David R., Cortez, Guillermo S., Bogen, Stéphane L., Rojas, Christian M.
Published in Angewandte Chemie International Edition (15.12.2000)
Published in Angewandte Chemie International Edition (15.12.2000)
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Journal Article
LONG-ACTING NATRIURETIC PEPTIDES AND USES THEREOF
ALSINA-FERNANDEZ, Jorge, CORTEZ, Guillermo S, LIU, Wen, WANG, Yan, ELMUCCIO, Michael Lawrence, BAKER, Hana Elisabeth, LOPES, Daniel Christopher, VALENZUELA, Francisco Alcides, MUPPIDI, Avinash, ZHANG, Lin
Year of Publication 31.10.2024
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Year of Publication 31.10.2024
Patent
LONG-ACTING NATRIURETIC PEPTIDES AND USES THEREOF
ALSINA-FERNANDEZ, Jorge, CORTEZ, Guillermo S, LIU, Wen, WANG, Yan, ELMUCCIO, Michael Lawrence, BAKER, Hana Elisabeth, LOPES, Daniel Christopher, VALENZUELA, Francisco Alcides, MUPPIDI, Avinash, ZHANG, Lin
Year of Publication 12.09.2024
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Year of Publication 12.09.2024
Patent
LONG-ACTING NATRIURETIC PEPTIDES AND USES THEREOF
ALSINA-FERNANDEZ, Jorge, CORTEZ, Guillermo S, LIU, Wen, WANG, Yan, ELMUCCIO, Michael Lawrence, BAKER, Hana Elisabeth, LOPES, Daniel Christopher, VALENZUELA, Francisco Alcides, MUPPIDI, Avinash, ZHANG, Lin
Year of Publication 30.05.2024
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Year of Publication 30.05.2024
Patent
LONG-ACTING NATRIURETIC PEPTIDES AND USES THEREOF
ALSINA-FERNANDEZ, Jorge, CORTEZ, Guillermo S, LIU, Wen, WANG, Yan, ELMUCCIO, Michael Lawrence, BAKER, Hana Elisabeth, LOPES, Daniel Christopher, VALENZUELA, Francisco Alcides, MUPPIDI, Avinash, ZHANG, Lin
Year of Publication 25.04.2024
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Year of Publication 25.04.2024
Patent
ERK inhibitors
Zhao, Gaiying, Joseph, Sajan, Rodriguez, Michael John, McMillen, William T, Cortez, Guillermo S, McLean, Johnathan Alexander
Year of Publication 13.07.2021
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Year of Publication 13.07.2021
Patent