Atlastins remodel the endoplasmic reticulum for selective autophagy
Liang, Jin Rui, Lingeman, Emily, Ahmed, Saba, Corn, Jacob E
Published in The Journal of cell biology (01.10.2018)
Published in The Journal of cell biology (01.10.2018)
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Journal Article
In vitro-transcribed guide RNAs trigger an innate immune response via the RIG-I pathway
Wienert, Beeke, Shin, Jiyung, Zelin, Elena, Pestal, Kathleen, Corn, Jacob E
Published in PLoS biology (16.07.2018)
Published in PLoS biology (16.07.2018)
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A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation
Liang, Jin Rui, Lingeman, Emily, Luong, Thao, Ahmed, Saba, Muhar, Matthias, Nguyen, Truc, Olzmann, James A., Corn, Jacob E.
Published in Cell (19.03.2020)
Published in Cell (19.03.2020)
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Journal Article
Cornerstones of CRISPR–Cas in drug discovery and therapy
Fellmann, Christof, Gowen, Benjamin G., Lin, Pei-Chun, Doudna, Jennifer A., Corn, Jacob E.
Published in Nature reviews. Drug discovery (01.02.2017)
Published in Nature reviews. Drug discovery (01.02.2017)
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Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq
Wienert, Beeke, Wyman, Stacia K, Richardson, Christopher D, Yeh, Charles D, Akcakaya, Pinar, Porritt, Michelle J, Morlock, Michaela, Vu, Jonathan T, Kazane, Katelynn R, Watry, Hannah L, Judge, Luke M, Conklin, Bruce R, Maresca, Marcello, Corn, Jacob E
Published in Science (American Association for the Advancement of Science) (19.04.2019)
Published in Science (American Association for the Advancement of Science) (19.04.2019)
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Journal Article
SLC19A1 transports immunoreactive cyclic dinucleotides
Luteijn, Rutger D., Zaver, Shivam A., Gowen, Benjamin G., Wyman, Stacia K., Garelis, Nick E., Onia, Liberty, McWhirter, Sarah M., Katibah, George E., Corn, Jacob E., Woodward, Joshua J., Raulet, David H.
Published in Nature (London) (01.09.2019)
Published in Nature (London) (01.09.2019)
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Journal Article
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
Horlbeck, Max A, Gilbert, Luke A, Villalta, Jacqueline E, Adamson, Britt, Pak, Ryan A, Chen, Yuwen, Fields, Alexander P, Park, Chong Yon, Corn, Jacob E, Kampmann, Martin, Weissman, Jonathan S
Published in eLife (23.09.2016)
Published in eLife (23.09.2016)
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USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria
Cunningham, Christian N., Baughman, Joshua M., Phu, Lilian, Tea, Joy S., Yu, Christine, Coons, Mary, Kirkpatrick, Donald S., Bingol, Baris, Corn, Jacob E.
Published in Nature cell biology (01.02.2015)
Published in Nature cell biology (01.02.2015)
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RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite
Fleishman, Sarel J, Leaver-Fay, Andrew, Corn, Jacob E, Strauch, Eva-Maria, Khare, Sagar D, Koga, Nobuyasu, Ashworth, Justin, Murphy, Paul, Richter, Florian, Lemmon, Gordon, Meiler, Jens, Baker, David
Published in PloS one (24.06.2011)
Published in PloS one (24.06.2011)
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Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
Fleishman, Sarel J., Whitehead, Timothy A., Ekiert, Damian C., Dreyfus, Cyrille, Corn, Jacob E., Strauch, Eva-Maria, Wilson, Ian A., Baker, David
Published in Science (American Association for the Advancement of Science) (13.05.2011)
Published in Science (American Association for the Advancement of Science) (13.05.2011)
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Journal Article
A prudent path forward for genomic engineering and germline gene modification
Baltimore, David, Berg, Paul, Botchan, Michael, Carroll, Dana, Charo, RAlta, Church, George, Corn, Jacob E, Daley, George Q, Doudna, Jennifer A, Fenner, Marsha, Greely, Henry T, Jinek, Martin, Martin, GSteven, Penhoet, Edward, Puck, Jennifer, Sternberg, Samuel H, Weissman, Jonathan S, Yamamoto, Keith R
Published in Science (American Association for the Advancement of Science) (03.04.2015)
Published in Science (American Association for the Advancement of Science) (03.04.2015)
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Journal Article
Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells
DeWitt, Mark A, Magis, Wendy, Bray, Nicolas L, Wang, Tianjiao, Berman, Jennifer R, Urbinati, Fabrizia, Heo, Seok-Jin, Mitros, Therese, Muñoz, Denise P, Boffelli, Dario, Kohn, Donald B, Walters, Mark C, Carroll, Dana, Martin, David I K, Corn, Jacob E
Published in Science translational medicine (12.10.2016)
Published in Science translational medicine (12.10.2016)
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Journal Article
Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering
Lee, Kunwoo, Mackley, Vanessa A, Rao, Anirudh, Chong, Anthony T, Dewitt, Mark A, Corn, Jacob E, Murthy, Niren
Published in eLife (02.05.2017)
Published in eLife (02.05.2017)
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Journal Article
Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair
Wienert, Beeke, Nguyen, David N., Guenther, Alexis, Feng, Sharon J., Locke, Melissa N., Wyman, Stacia K., Shin, Jiyung, Kazane, Katelynn R., Gregory, Georgia L., Carter, Matthew A. M., Wright, Francis, Conklin, Bruce R., Marson, Alex, Richardson, Chris D., Corn, Jacob E.
Published in Nature communications (30.04.2020)
Published in Nature communications (30.04.2020)
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Journal Article
Improving Gene Editing Outcomes in Human Hematopoietic Stem and Progenitor Cells by Temporal Control of DNA Repair
Lomova, Anastasia, Clark, Danielle N., Campo‐Fernandez, Beatriz, Flores‐Bjurström, Carmen, Kaufman, Michael L., Fitz‐Gibbon, Sorel, Wang, Xiaoyan, Miyahira, Eric Y., Brown, Devin, DeWitt, Mark A., Corn, Jacob E., Hollis, Roger P., Romero, Zulema, Kohn, Donald B.
Published in Stem cells (Dayton, Ohio) (01.02.2019)
Published in Stem cells (Dayton, Ohio) (01.02.2019)
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Journal Article
Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair
Lee, Kunwoo, Conboy, Michael, Park, Hyo Min, Jiang, Fuguo, Kim, Hyun Jin, Dewitt, Mark A., Mackley, Vanessa A., Chang, Kevin, Rao, Anirudh, Skinner, Colin, Shobha, Tamanna, Mehdipour, Melod, Liu, Hui, Huang, Wen-chin, Lan, Freeman, Bray, Nicolas L., Li, Song, Corn, Jacob E., Kataoka, Kazunori, Doudna, Jennifer A., Conboy, Irina, Murthy, Niren
Published in Nature biomedical engineering (2017)
Published in Nature biomedical engineering (2017)
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Journal Article
Suppression of unwanted CRISPR-Cas9 editing by co-administration of catalytically inactivating truncated guide RNAs
Rose, John C., Popp, Nicholas A., Richardson, Christopher D., Stephany, Jason J., Mathieu, Julie, Wei, Cindy T., Corn, Jacob E., Maly, Dustin J., Fowler, Douglas M.
Published in Nature communications (01.06.2020)
Published in Nature communications (01.06.2020)
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Journal Article
Disabling Cas9 by an anti-CRISPR DNA mimic
Shin, Jiyung, Jiang, Fuguo, Liu, Jun-Jie, Bray, Nicolas L, Rauch, Benjamin J, Baik, Seung Hyun, Nogales, Eva, Bondy-Denomy, Joseph, Corn, Jacob E, Doudna, Jennifer A
Published in Science advances (01.07.2017)
Published in Science advances (01.07.2017)
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