487 NC410, a fusion protein of LAIR-2 (Leukocyte Associated Immunoglobulin-like Receptor) with human IgG1 Fc, is safe & tolerable with evidence of immune modulation in subjects with advanced solid tumors
Myint, Han, Tian, Linjie, Shaik, Jahangheer, Barbu, Emilia, Zhou, Qinjie, Morawski, Aaron, Abukharma, Hasan, Liu, Linda, Shin, John, Flies, Dallas, Copeland, Ron, Nelson, Megan, Zeidan, Stephanie, Bilusic, Marijo, Pastor, Danielle, Madan, Ravi, Fu, Siqing, Gutierrez, Martin, Langermann, Solomon
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
A Novel Lair-1 Antibody Selectively Targets Acute Myeloid Leukemia (AML) Stem Cells
Tian, Linjie, Paucarmayta, Ana, Lovewell, Rustin, Maloveste, Karla, Hong, Junshik, Hedgepath, Carly, Kim, Kwang Woon, Copeland, Ron, O'Neill, Thomas, Patel, Shashank, Liu, Linda N., Myint, Han, Langermann, Solomon, Flies, Dallas B, Kim, Tae Kon
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
A Phase 1, Open-Label, Safety, Tolerability, and Efficacy Study of NC525 in Subjects with Advanced Myeloid Neoplasms
Short, Nicholas, Kim, Tae Kon, Lovewell, Rustin, Griffiths, Elizabeth A., Carraway, Hetty E., Zeidan, Stephanie, Knowles, Elizabeth, Nelson, Megan, Shaik, Jahangheer, Zhou, Chelsea, Barbu, Emilia Alina, Cusumano, Zachary, Kundu, Subhadip, Sharee, Sasan, Copeland, Ron, Flies, Dallas, Langermann, Solomon, Myint, Han, Altman, Jessica K., Ravandi, Farhad
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
739 A phase 1b/2, open-label, safety, tolerability and efficacy study of NC410 plus pembrolizumab for participants with immune checkpoint inhibitor (ICI) refractory, or MSS/MSI-low ICI naïve advanced or metastatic solid tumors
Myint, Han, Christenson, Eric, Fu, Siqing, Gutierrez, Martin, Martz, Ashley, Zeidan, Stephanie, Nelson, Megan, Barbu, Alina, Morawski, Aaron, Zhou, Chelsea, Cusumano, Zachary, Rachel O’Neill, Copeland, Ron, Flies, Dallas, Solomon Langermann, Cohen, Julia, Le, Dung
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article
748 A phase 1/2, open-label, dose-escalation, safety and tolerability study of NC762 in subjects with advanced or metastatic solid tumors
Myint, Han, Shah, Satish, Gutierrez, Martin, Zsiros, Emese, Nelson, Megan, Zeidan, Stephanie, Myrthil, Nadia, Morawski, Aaron, Barbu, Alina, Shaik, Jahangheer, Zhou, Chelsea, Kanellopoulou, Chrysi, Copeland, Ron, Cusumano, Zachary, Flies, Dallas, Solomon Langermann, Lorusso, Patricia, Odunsi, Kunle
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article