Safety, tolerability, and preliminary activity of CUDC-907, a first-in-class, oral, dual inhibitor of HDAC and PI3K, in patients with relapsed or refractory lymphoma or multiple myeloma: an open-label, dose-escalation, phase 1 trial
Younes, Anas, Dr, Berdeja, Jesus G, MD, Patel, Manish R, MD, Flinn, Ian, MD, Gerecitano, John F, MD, Neelapu, Sattva S, MD, Kelly, Kevin R, MD, Copeland, Amanda R, MSN, Akins, Amy, BSN, Clancy, Myles S, MBA, Gong, Lucy, PharmD, Wang, Jing, PhD, Ma, Anna, MS, Viner, Jaye L, MD, Oki, Yasuhiro, MD
Published in The lancet oncology (01.05.2016)
Published in The lancet oncology (01.05.2016)
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Time from diagnosis to 2nd treatment is a promising surrogate for overall survival in patients with advanced stage follicular lymphoma
Soumerai, Jacob D., Ni, Andy, Alperovich, Anna, Batlevi, Connie, Bantilan, Kurt S., Fischer, Thais, Copeland, Amanda R., Smith, Katy, Ying, Zhitao, Younes, Anas, Zelenetz, Andrew D.
Published in Leukemia & lymphoma (14.10.2020)
Published in Leukemia & lymphoma (14.10.2020)
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Phase 2 study of rituximab plus ABVD in patients with newly diagnosed classical Hodgkin lymphoma
Younes, Anas, Oki, Yasuhiro, McLaughlin, Peter, Copeland, Amanda R., Goy, Andre, Pro, Barbara, Feng, Lei, Yuan, Ying, Chuang, Hubert H., Macapinlac, Homer A., Hagemeister, Fredrick, Romaguera, Jorge, Samaniego, Felipe, Fanale, Michelle A., Dabaja, Bouthaina Shbib, Rodriguez, Maria A., Dang, Nam, Kwak, Larry W., Neelapu, Sattva S., Fayad, Luis E.
Published in Blood (03.05.2012)
Published in Blood (03.05.2012)
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Journal Article
Phase-I and randomized phase-II trial of panobinostat in combination with ICE (ifosfamide, carboplatin, etoposide) in relapsed or refractory classical Hodgkin lymphoma
Hu, Bei, Younes, Anas, Westin, Jason R., Turturro, Francesco, Claret, Linda, Feng, Lei, Fowler, Nathan, Neelapu, Sattva, Romaguera, Jorge, Hagemeister, Fredrick B., Rodriguez, Maria Alma, Samaniego, Felipe, Fayad, Luis E., Copeland, Amanda R., Nastoupil, Loretta J., Nieto, Yago, Fanale, Michelle A., Oki, Yasuhiro
Published in Leukemia & lymphoma (03.04.2018)
Published in Leukemia & lymphoma (03.04.2018)
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Journal Article
Integrated DNA/RNA targeted genomic profiling of diffuse large B-cell lymphoma using a clinical assay
Intlekofer, Andrew M., Joffe, Erel, Batlevi, Connie L., Hilden, Patrick, He, Jie, Seshan, Venkatraman E., Zelenetz, Andrew D., Palomba, M. Lia, Moskowitz, Craig H., Portlock, Carol, Straus, David J., Noy, Ariela, Horwitz, Steven M., Gerecitano, John F., Moskowitz, Alison, Hamlin, Paul, Matasar, Matthew J, Kumar, Anita, van den Brink, Marcel R., Knapp, Kristina M., Pichardo, Janine D., Nahas, Michelle K., Trabucco, Sally E., Mughal, Tariq, Copeland, Amanda R., Papaemmanuil, Elli, Moarii, Mathai, Levine, Ross L., Dogan, Ahmet, Miller, Vincent A., Younes, Anas
Published in Blood cancer journal (New York) (12.06.2018)
Published in Blood cancer journal (New York) (12.06.2018)
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Journal Article
The Final Report of a Phase I/II Study of Panobinostat in Combination with ICE (Ifosfamide, Carboplatin and Etoposide) in Patients (pts) with Relapsed or Refractory (R/R) Classical Hodgkin Lymphoma (cHL)
Hu, Bei, Younes, Anas, Claret, Linda, Feng, Lei, Westin, Jason R., Fowler, Nathan, Neelapu, Sattva, Hagemeister, Fredrick B., Rodriguez, Maria Alma, Samaniego, Felipe, Fayad, Luis E., Nastoupil, Loretta J., Copeland, Amanda R, Fanale, Michelle A, Oki, Yasuhiro
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Association of MHC-II, PD-L1, and FoxP3 with Disease Status and Outcomes in Patients with Hodgkin Lymphoma
Vardhana, Santosha A., Ozkaya, Neval, Matsuki, Eri, Pichardo, Janine D., Moskowitz, Alison J., Straus, David J, Copeland, Amanda R, Ni, Ai, Jungbluth, Achim A, Moskowitz, Craig H, Dogan, Ahmet, Younes, Anas
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Phase 1 safety and dose escalation of CUDC-907, a first-in-class, oral, dual inhibitor of HDAC and PI3K in relapsed or refractory lymphoma and multiple myeloma
Younes, Anas, Berdeja, Jesus G., Patel, Manish R., Flinn, Ian, Gerecitano, John F., Neelapu, Sattva S., Kelly, Kevin R., Copeland, Amanda R., Akins, Amy, Clancy, Myles S., Gong, Lucy, Wang, Jing, Ma, Anna, Viner, Jaye L., Oki, Yasuhiro
Published in The lancet oncology (31.03.2016)
Published in The lancet oncology (31.03.2016)
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Journal Article
Phase 1 Trial Testing Single Agent CUDC-907, a Novel, Oral Dual Inhibitor of Histone Deacetylase (HDAC) and PI3K: Initial Assessment of Patients with Relapsed or Refractory (RR) Diffuse Large B-Cell Lymphoma (DLBCL), Including Double Expressor (DE) Lymphoma
Younes, Anas, Berdeja, Jesus G., Patel, Manish R., Kelly, Kevin R., Flinn, Ian W., Gerecitano, John F, Neelapu, Sattva S., Copeland, Amanda R., Akins, Amy, Clancy, Myles, Ma, Anna, Sun, Kaiming, Tian, Ze, Wang, Jing, Viner, Jaye, Oki, Yasuhiro
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Intervention Versus Observation: What Is the Appropriate Endpoint? Assessment of Endpoints in Patients with Advanced Stage Follicular Lymphoma Who Are Initially Observed
Soumerai, Jacob D, Bantilan, Kurt S, Ni, Ai, Batlevi, Connie, Alperovich, Anna, Smith, Katy, Ying, Zhitao, Copeland, Amanda R, Matasar, Matthew J., Straus, David J, Gerecitano, John F, Hamlin, Paul A, Horwitz, Steven M, Portlock, Carol S, Palomba, Maria Lia, Moskowitz, Craig H, Moskowitz, Alison J, Noy, Ariela, Sauter, Craig S, Kumar, Anita, Intlekofer, Andrew M, Caron, Philip, Drullinsky, Pamela, Younes, Anas, Zelenetz, Andrew D
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Outcomes of Follicular Lymphoma Patients By Dynamic FLIPI at Diagnosis and Initial Treatment in the Post-Rituximab Era
Batlevi, Connie, Alperovich, Anna, Smith, Katy, Ying, Zhitao, Soumerai, Jacob D, Copeland, Amanda R, Joffe, Erel, Caron, Philip, Drullinsky, Pamela, Gerecitano, John F, Hamilton, Audrey, Hamlin, Paul A, Horwitz, Steven M, Intlekofer, Andrew M, Kumar, Anita, Matasar, Matthew J., Moskowitz, Alison J., Moskowitz, Craig H, Noy, Ariela, Palomba, Maria Lia, Portlock, Carol S, Sauter, Craig S, Straus, David J, Zelenetz, Andrew D., Ni, Ai, Seshan, Venkatraman E, Younes, Anas
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Benchmark of Progression Free Survival for Multiple Lines of Therapy in Follicular Lymphoma Treated in the Rituximab Era
Alperovich, Anna, Batlevi, Connie, Smith, Katy, Ying, Zhitao, Soumerai, Jacob D, Copeland, Amanda R, Joffe, Erel, Caron, Philip, Drullinsky, Pamela, Gerecitano, John F, Hamilton, Audrey, Hamlin, Paul A, Horwitz, Steven M, Intlekofer, Andrew M, Kumar, Anita, Matasar, Matthew J, Moskowitz, Alison J., Moskowitz, Craig H, Noy, Ariela, Palomba, Maria Lia, Portlock, Carol S, Sauter, Craig S, Straus, David J, Zelenetz, Andrew D., Ni, Ai, Seshan, Venkatraman E, Younes, Anas
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Phase II Study of an AKT Inhibitor MK2206 in Patients with Relapsed or Refractory Lymphoma
Oki, Yasuhiro, Fanale, Michelle A., Romaguera, Jorge E., Fayad, Luis, Fowler, Nathan, Copeland, Amanda R.M., Samaniego, Felipe, Kwak, Larry W., Neelapu, Sattva S, Wang, Michael, Feng, Lei, Younes, Anas
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Distinctive Genomic Alterations in Testicular Diffuse Large B Cell Lymphoma
Batlevi, Connie, Rapaport, Franck, Wang, Lu, Intlekofer, Andrew M., Copeland, Amanda R., Jungbluth, Achim A, Reiner, Anne, Pichardo, Janine D., Gallagher, Meighan, Bouvier, Nancy, Socci, Nicholas D., Criscuolo, Frederick, Schultz, Nikolaus, Arcila, Maria, Berger, Michael, Zelenetz, Andrew D, Seshan, Venkatraman E, Dogan, Ahmet, Younes, Anas
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Defining the Incidence and Clinical Impact of Genomic Alterations Across Different Histologic Types of Lymphoma Using a Clinically Validated Comprehensive Targeted Sequencing Assay
Batlevi, Connie, Rapaport, Franck, Intlekofer, Andrew M., Reiner, Anne, Moskowitz, Craig H, Horwitz, Steven M, Zelenetz, Andrew D, Palomba, Lia, Moskowitz, Alison J, Gerecitano, John F., Hamlin, Paul A, Copeland, Amanda R., Matasar, Matthew J, Sauter, Craig S., Kumar, Anita, Noy, Ariela, Straus, David J., Portlock, Carol S., Criscuolo, Frederick, He, Jie, Royston, Daniel, Balasubramanian, Sohail, Reznikovskaya, Yekaterina, Pichardo, Janine D., Stephens, Phil, Miller, Vincent, Levine, Ross L., Seshan, Venkatraman, Dogan, Ahmet, Younes, Anas
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
The HDAC Inhibitor Entinostat (SNDX-275) Induces Clinical Responses in Patients with Relapsed and Refractory Hodgkin's Lymphoma: Results of ENGAGE-501 Multicenter Phase 2 Study
Younes, Anas, Hernandez, Francisco, Bociek, R. Gregory, Kasamon, Yvette L., Lee, Peter, Gore, Lia, Copeland, Amanda R
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article
Identification of Actionable Genomic Alterations Across Different Lymphoma Histologies Using a Comprehensive Next Generation Genomic Sequencing Clinical Assay
Batlevi, Connie, Moskowitz, Craig H., Zelenetz, Andrew D., Horwitz, Steven M., Palomba, Lia, Gerecitano, John F., Copeland, Amanda R.M., Hamlin, Paul, Matasar, Matthew J., Sauter, Craig S., Moskowitz, Alison J, Noy, Ariela, Straus, David J., Portlock, Carol S, Mazzei, Colleen, Pichardo, Janine D., Miller, Vincent, Stephens, Phil J, He, Jie, Feldstein, Julie T, Levine, Ross L., Dogan, Ahmet, Younes, Anas
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Genomic Profiling Combining DNA and RNA Analysis of 112 Formalin-Fixed Paraffin-Embedded Diffuse Large B Cell Lymphoma Specimens Identifies a High Frequency of Clinically Relevant Genomic Alterations
Intlekofer, Andrew M., Hilden, Patrick, Seshan, Venkatraman E., Copeland, Amanda R., Levine, Ross L., Zelenetz, Andrew D., Teruya-Feldstein, Julie, Dogan, Ahmet, Palomba, Maria Lia, Moskowitz, Craig H., van den Brink, Marcel R.M., Knapp, Kristina M., Pichardo, Janine D., Brennan, Kristina W., Young, Geneva, He, Jie, Nahas, Michelle K., Yelensky, Roman, Otto, Geoff A., Lipson, Doron, Stephens, Philip J., Miller, Vincent A., Younes, Anas
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Profiling Genomic Alterations Of Diffuse Large B-Cell Lymphoma (DLBCL) At Diagnosis, Relapse, and Transformation, Using a Novel Clinical Diagnostic Targeted Sequencing Platform
Intlekofer, Andrew M., Sheshan, Venkatraman E., Levine, Ross L., Zelenetz, Andrew D., Teruya-Feldstein, Julie, Dogan, Ahmet, Palomba, Maria Lia, Moskowitz, Craig H., van den Brink, Marcel R.M., Knapp, Kristina M., Copeland, Amanda R.M., Pichardo, Janine D., Brennan, Kristina W., Young, Geneva, He, Jie, Nahas, Michelle K., Yelensky, Roman, Otto, Geoff A., Lipson, Doron, Stephens, Philip J., Miller, Vincent A., Younes, Anas
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
Phase-I Study of the Novel Oral JAK-2 Inhibitor SB1518 in Patients with Relapsed Lymphoma: Evidence of Clinical and Biologic Activity
Younes, Anas, Fanale, Michelle, McLaughlin, Peter, Copeland, Amanda R, de Castro Faria, Silvana, Wood, Jeanette, Ethirajulu, Kantharaj, Zhu, Huan J.
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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