A model for the evolution of prokaryotic DNA restriction-modification systems based upon the structural malleability of Type I restriction-modification enzymes
Bower, Edward K M, Cooper, Laurie P, Roberts, Gareth A, White, John H, Luyten, Yvette, Morgan, Richard D, Dryden, David T F
Published in Nucleic acids research (28.09.2018)
Published in Nucleic acids research (28.09.2018)
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Impact of target site distribution for Type I restriction enzymes on the evolution of methicillin-resistant Staphylococcus aureus (MRSA) populations
Roberts, Gareth A, Houston, Patrick J, White, John H, Chen, Kai, Stephanou, Augoustinos S, Cooper, Laurie P, Dryden, David T F, Lindsay, Jodi A
Published in Nucleic acids research (01.08.2013)
Published in Nucleic acids research (01.08.2013)
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Extensive DNA mimicry by the ArdA anti-restriction protein and its role in the spread of antibiotic resistance
McMahon, Stephen A, Roberts, Gareth A, Johnson, Kenneth A, Cooper, Laurie P, Liu, Huanting, White, John H, Carter, Lester G, Sanghvi, Bansi, Oke, Muse, Walkinshaw, Malcolm D, Blakely, Garry W, Naismith, James H, Dryden, David T.F
Published in Nucleic acids research (01.08.2009)
Published in Nucleic acids research (01.08.2009)
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Quantification of Photosensitized Singlet Oxygen Production by a Fluorescent Protein
Ragàs, Xavier, Cooper, Laurie P., White, John H., Nonell, Santi, Flors, Cristina
Published in Chemphyschem (17.01.2011)
Published in Chemphyschem (17.01.2011)
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DNA target recognition domains in the Type I restriction and modification systems of Staphylococcus aureus
Cooper, Laurie P, Roberts, Gareth A, White, John H, Luyten, Yvette A, Bower, Edward K M, Morgan, Richard D, Roberts, Richard J, Lindsay, Jodi A, Dryden, David T F
Published in Nucleic acids research (07.04.2017)
Published in Nucleic acids research (07.04.2017)
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Exploring the DNA mimicry of the Ocr protein of phage T7
Roberts, Gareth A, Stephanou, Augoustinos S, Kanwar, Nisha, Dawson, Angela, Cooper, Laurie P, Chen, Kai, Nutley, Margaret, Cooper, Alan, Blakely, Garry W, Dryden, David T F
Published in Nucleic acids research (01.09.2012)
Published in Nucleic acids research (01.09.2012)
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Journal Article
Structure and operation of the DNA-translocating type I DNA restriction enzymes
Kennaway, Christopher K, Taylor, James E N, Song, Chun Feng, Potrzebowski, Wojciech, Nicholson, William, White, John H, Swiderska, Anna, Obarska-Kosinska, Agnieszka, Callow, Philip, Cooper, Laurie P, Roberts, Gareth A, Artero, Jean-Baptiste, Bujnicki, Janusz M, Trinick, John, Kneale, G Geoff, Dryden, David T F
Published in Genes & development (01.01.2012)
Published in Genes & development (01.01.2012)
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Journal Article
The structure of M.EcoKI Type I DNA methyltransferase with a DNA mimic antirestriction protein
Kennaway, Christopher K., Obarska-Kosinska, Agnieszka, White, John H., Tuszynska, Irina, Cooper, Laurie P., Bujnicki, Janusz M., Trinick, John, Dryden, David T. F.
Published in Nucleic acids research (01.02.2009)
Published in Nucleic acids research (01.02.2009)
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Journal Article
ArdA proteins from different mobile genetic elements can bind to the EcoKI Type I DNA methyltransferase of E. coli K12
Chen, Kai, Reuter, Marcel, Sanghvi, Bansi, Roberts, Gareth A., Cooper, Laurie P., Tilling, Matthew, Blakely, Garry W., Dryden, David T.F.
Published in Biochimica et biophysica acta (01.03.2014)
Published in Biochimica et biophysica acta (01.03.2014)
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Journal Article
Atomic force microscopy of the EcoKI Type I DNA restriction enzyme bound to DNA shows enzyme dimerization and DNA looping
Neaves, Kelly J, Cooper, Laurie P, White, John H, Carnally, Stewart M, Dryden, David T.F, Edwardson, J. Michael, Henderson, Robert M
Published in Nucleic acids research (01.04.2009)
Published in Nucleic acids research (01.04.2009)
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Removal of a frameshift between the hsdM and hsdS genes of the EcoKI Type IA DNA restriction and modification system produces a new type of system and links the different families of Type I systems
Roberts, Gareth A, Chen, Kai, Cooper, Laurie P, White, John H, Blakely, Garry W, Dryden, David T F
Published in Nucleic acids research (01.11.2012)
Published in Nucleic acids research (01.11.2012)
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Mutations of the domain forming the dimeric interface of the ArdA protein affect dimerization and antimodification activity but not antirestriction activity
Roberts, Gareth A., Chen, Kai, Bower, Edward K. M., Madrzak, Julia, Woods, Arcadia, Barker, Amy M., Cooper, Laurie P., White, John H., Blakely, Garry W., Manfield, Iain, Dryden, David T. F.
Published in The FEBS journal (01.10.2013)
Published in The FEBS journal (01.10.2013)
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Journal Article
The Orf18 gene product from conjugative transposon Tn916 is an ArdA antirestriction protein that inhibits type I DNA restriction-modification systems
Serfiotis-Mitsa, Dimitra, Roberts, Gareth A, Cooper, Laurie P, White, John H, Nutley, Margaret, Cooper, Alan, Blakely, Garry W, Dryden, David T F
Published in Journal of molecular biology (28.11.2008)
Published in Journal of molecular biology (28.11.2008)
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Journal Article
An investigation of the structural requirements for ATP hydrolysis and DNA cleavage by the EcoKI Type I DNA restriction and modification enzyme
Roberts, Gareth A., Cooper, Laurie P., White, John H., Su, Tsueu-Ju, Zipprich, Jakob T., Geary, Paul, Kennedy, Cowan, Dryden, David T. F.
Published in Nucleic acids research (01.09.2011)
Published in Nucleic acids research (01.09.2011)
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The Type I Restriction Enzymes as Barriers to Horizontal Gene Transfer: Determination of the DNA Target Sequences Recognised by Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complexes 133/ST771 and 398
Chen, Kai, Stephanou, Augoustinos S, Roberts, Gareth A, White, John H, Cooper, Laurie P, Houston, Patrick J, Lindsay, Jodi A, Dryden, David T F
Published in Advances in experimental medicine and biology (01.01.2016)
Published in Advances in experimental medicine and biology (01.01.2016)
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Fusion of GFP to the M.EcoKI DNA methyltransferase produces a new probe of Type I DNA restriction and modification enzymes
Chen, Kai, Roberts, Gareth A., Stephanou, Augoustinos S., Cooper, Laurie P., White, John H., Dryden, David T.F.
Published in Biochemical and biophysical research communications (23.07.2010)
Published in Biochemical and biophysical research communications (23.07.2010)
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Journal Article
Dissection of the DNA Mimicry of the Bacteriophage T7 Ocr Protein using Chemical Modification
Stephanou, Augoustinos S., Roberts, Gareth A., Cooper, Laurie P., Clarke, David J., Thomson, Andrew R., MacKay, C. Logan, Nutley, Margaret, Cooper, Alan, Dryden, David T.F.
Published in Journal of molecular biology (21.08.2009)
Published in Journal of molecular biology (21.08.2009)
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