Ublituximab for the treatment of CD20 positive B-cell malignancies
Babiker, Hani M, Glode, Ashley E, Cooke, Laurence S, Mahadevan, Daruka
Published in Expert opinion on investigational drugs (03.04.2018)
Published in Expert opinion on investigational drugs (03.04.2018)
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Carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6) in Pancreatic Ductal Adenocarcinoma (PDA): An integrative analysis of a novel therapeutic target
Pandey, Ritu, Zhou, Muhan, Islam, Shariful, Chen, Baowei, Barker, Natalie K, Langlais, Paul, Srivastava, Anup, Luo, Moulun, Cooke, Laurence S, Weterings, Eric, Mahadevan, Daruka
Published in Scientific reports (04.12.2019)
Published in Scientific reports (04.12.2019)
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Reciprocal feedback inhibition of the androgen receptor and PI3K as a novel therapy for castrate-sensitive and -resistant prostate cancer
Qi, Wenqing, Morales, Carla, Cooke, Laurence S, Johnson, Benny, Somer, Bradley, Mahadevan, Daruka
Published in Oncotarget (08.12.2015)
Published in Oncotarget (08.12.2015)
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A novel small molecule inhibitor of the DNA repair protein Ku70/80
Weterings, Eric, Gallegos, Alfred C., Dominick, Lauren N., Cooke, Laurence S., Bartels, Trace N., Vagner, Josef, Matsunaga, Terry O., Mahadevan, Daruka
Published in DNA repair (01.07.2016)
Published in DNA repair (01.07.2016)
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Journal Article
Alisertib added to rituximab and vincristine is synthetic lethal and potentially curative in mice with aggressive DLBCL co-overexpressing MYC and BCL2
Mahadevan, Daruka, Morales, Carla, Cooke, Laurence S, Manziello, Ann, Mount, David W, Persky, Daniel O, Fisher, Richard I, Miller, Thomas P, Qi, Wenqing
Published in PloS one (03.06.2014)
Published in PloS one (03.06.2014)
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Journal Article
Disruption of Aneuploidy and Senescence Induced by Aurora Inhibition Promotes Intrinsic Apoptosis in Double Hit or Double Expressor Diffuse Large B-cell Lymphomas
Islam, Shariful, Qi, Wenqing, Morales, Carla, Cooke, Laurence, Spier, Catherine, Weterings, Eric, Mahadevan, Daruka
Published in Molecular cancer therapeutics (01.10.2017)
Published in Molecular cancer therapeutics (01.10.2017)
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Aurora A Inhibitor (MLN8237) plus Vincristine plus Rituximab Is Synthetic Lethal and a Potential Curative Therapy in Aggressive B-cell Non-Hodgkin Lymphoma
MAHADEVAN, Daruka, STEJSKAL, Amy, COOKE, Laurence S, MANZIELLO, Ann, MORALES, Carla, PERSKY, Daniel O, FISHER, Richard I, MILLER, Thomas P, WENQING QI
Published in Clinical cancer research (15.04.2012)
Published in Clinical cancer research (15.04.2012)
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AT9283, a novel aurora kinase inhibitor, suppresses tumor growth in aggressive B-cell lymphomas
Qi, Wenqing, Liu, Xiaobing, Cooke, Laurence S., Persky, Daniel O., Miller, Thomas P., Squires, Matthew, Mahadevan, Daruka
Published in International journal of cancer (15.06.2012)
Published in International journal of cancer (15.06.2012)
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Aurora inhibitor MLN8237 in combination with docetaxel enhances apoptosis and anti-tumor activity in mantle cell lymphoma
Qi, Wenqing, Cooke, Laurence S., Liu, Xiaobing, Rimsza, Lisa, Roe, Denise J., Persky, Ann Manziolli. Daniel O., Miller, Thomas P., Mahadevan, Daruka
Published in Biochemical pharmacology (01.04.2011)
Published in Biochemical pharmacology (01.04.2011)
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Novel receptor tyrosine kinase targeted combination therapies for imatinib-resistant gastrointestinal stromal tumors (GIST)
Mahadevan, Daruka, Theiss, Noah, Morales, Carla, Stejskal, Amy E, Cooke, Laurence S, Zhu, Min, Kurtzman, Drew, Swart, Rachel, Ong, Evan, Qi, Wenqing
Published in Oncotarget (10.02.2015)
Published in Oncotarget (10.02.2015)
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Journal Article
TP53 Mutations as a Driver of Metastasis Signaling in Advanced Cancer Patients
Pandey, Ritu, Johnson, Nathan, Cooke, Laurence, Johnson, Benny, Chen, Yuliang, Pandey, Manjari, Chandler, Jason, Mahadevan, Daruka
Published in Cancers (03.02.2021)
Published in Cancers (03.02.2021)
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Journal Article
Alisertib (MLN8237) an investigational agent suppresses Aurora A and B activity, inhibits proliferation, promotes endo-reduplication and induces apoptosis in T-NHL cell lines supporting its importance in PTCL treatment
Qi, Wenqing, Spier, Catherine, Liu, Xiaobing, Agarwal, Amit, Cooke, Laurence S, Persky, Daniel O, Chen, Deyu, Miller, Thomas P, Mahadevan, Daruka
Published in Leukemia research (01.04.2013)
Published in Leukemia research (01.04.2013)
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Journal Article
Design and Activity of a Murine and Humanized Anti-CEACAM6 Single-Chain Variable Fragment in the Treatment of Pancreatic Cancer
RILEY, Christopher J, ENGELHARDT, Kevin P, NAGLE, Raymond B, GAREWAL, Harinder, VON HOFF, Daniel D, MAHADEVAN, Daruka, SALDANHA, Jose W, WENQING QI, COOKE, Laurence S, YINGTING ZHU, NARAYAN, Satya T, SHAKALYA, Kishore, CROCE, Kimiko Della, GEORGIEV, Ivan G
Published in Cancer research (Chicago, Ill.) (01.03.2009)
Published in Cancer research (Chicago, Ill.) (01.03.2009)
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An Analog of Withaferin A Activates the MAPK and Glutathione "Stress" Pathways and Inhibits Pancreatic Cancer Cell Proliferation
Liu, Xiaobing, Qi, Wenqing, Cooke, Laurence S., Kithsiri Wijeratne, E. M., Xu, Ya-ming, Marron, Marilyn T., Leslie Gunatilaka, A. A., Mahadevan, Daruka
Published in Cancer investigation (15.11.2011)
Published in Cancer investigation (15.11.2011)
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Journal Article
Monoclonal antibody therapies targeting pancreatic ductal adenocarcinoma
Engelhardt, Kevin, Riley, Christopher, Cooke, Laurence, Mahadevan, Daruka
Published in Current drug discovery technologies (01.12.2006)
Published in Current drug discovery technologies (01.12.2006)
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Novel mutational and pathway signatures in relapsed/refractory colorectal cancer patients
Johnson, Benny, Cooke, Laurence, Mahadevan, Daruka
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Novel mutational and pathway signatures in relapsed/refractory colorectal cancer patients
Johnson, Benny, Cooke, Laurence, Mahadevan, Daruka
Published in Journal of clinical oncology (01.02.2016)
Published in Journal of clinical oncology (01.02.2016)
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Journal Article
Drug-induced aneuploidy and polyploidy is a mechanism of disease relapse in MYC/BCL2-addicted diffuse large B-cell lymphoma
Islam, Shariful, Paek, Andrew L, Hammer, Michael, Rangarajan, Savithri, Ruijtenbeek, Robert, Cooke, Laurence, Weterings, Eric, Mahadevan, Daruka
Published in Oncotarget (13.11.2018)
Published in Oncotarget (13.11.2018)
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