Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia
Sasu, Barbra J., Cooke, Keegan S., Arvedson, Tara L., Plewa, Cherylene, Ellison, Aaron R., Sheng, Jackie, Winters, Aaron, Juan, Todd, Li, Hongyan, Begley, C. Glenn, Molineux, Graham
Published in Blood (29.04.2010)
Published in Blood (29.04.2010)
Get full text
Journal Article
Molecular Mechanism of Hepcidin-Mediated Ferroportin Internalization Requires Ferroportin Lysines, Not Tyrosines or JAK-STAT
Ross, Sandra L., Tran, Lynn, Winters, Aaron, Lee, Ki-Jeong, Plewa, Cherylene, Foltz, Ian, King, Chadwick, Miranda, Les P., Allen, Jennifer, Beckman, Holger, Cooke, Keegan S., Moody, Gordon, Sasu, Barbra J., Nemeth, Elizabeta, Ganz, Tomas, Molineux, Graham, Arvedson, Tara L.
Published in Cell metabolism (06.06.2012)
Published in Cell metabolism (06.06.2012)
Get full text
Journal Article
A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates
Cooke, Keegan S., Hinkle, Beth, Salimi-Moosavi, Hossein, Foltz, Ian, King, Chadwick, Rathanaswami, Palaniswami, Winters, Aaron, Steavenson, Shirley, Begley, C. Glenn, Molineux, Graham, Sasu, Barbra J.
Published in Blood (24.10.2013)
Published in Blood (24.10.2013)
Get full text
Journal Article
IL-22 regulates iron availability in vivo through the induction of hepcidin
Smith, Carole L, Arvedson, Tara L, Cooke, Keegan S, Dickmann, Leslie J, Forte, Carla, Li, Hongyan, Merriam, Kimberly L, Perry, V Kristina, Tran, Linh, Rottman, James B, Maxwell, Joseph R
Published in The Journal of immunology (1950) (15.08.2013)
Published in The Journal of immunology (1950) (15.08.2013)
Get full text
Journal Article
OncoVEXmGM-CSFexpands tumor antigen-specific CD8+ T-cell response in preclinical models
Estrada, Juan, Zhan, Jinghui, Mitchell, Petia, Werner, Jonathan, Beltran, Pedro J, DeVoss, Jason, Qing, Jing, Cooke, Keegan S
Published in Journal for immunotherapy of cancer (01.05.2023)
Published in Journal for immunotherapy of cancer (01.05.2023)
Get full text
Journal Article
Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus
Gardenghi, Sara, Renaud, Tom M., Meloni, Alessandra, Casu, Carla, Crielaard, Bart J., Bystrom, Laura M., Greenberg-Kushnir, Noa, Sasu, Barbra J., Cooke, Keegan S., Rivella, Stefano
Published in Blood (20.02.2014)
Published in Blood (20.02.2014)
Get full text
Journal Article
Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer
Chou, Jonathan, Egusa, Emily A, Wang, Sinan, Badura, Michelle L, Lee, Fei, Bidkar, Anil P, Zhu, Jun, Shenoy, Tanushree, Trepka, Kai, Robinson, Troy M, Steri, Veronica, Huang, Jiaoti, Wang, Yuzhuo, Small, Eric J, Chan, Emily, Stohr, Bradley A, Ashworth, Alan, Delafontaine, Brant, Rottey, Sylvie, Cooke, Keegan S, Hashemi Sadraei, Nooshin, Yu, Brian, Salvati, Mark, Bailis, Julie M, Feng, Felix Y, Flavell, Robert R, Aggarwal, Rahul
Published in Cancer research (Chicago, Ill.) (18.01.2023)
Published in Cancer research (Chicago, Ill.) (18.01.2023)
Get full text
Journal Article
AMG 509 (Xaluritamig), an Anti-STEAP1 XmAb 2+1 T-cell Redirecting Immune Therapy with Avidity-Dependent Activity against Prostate Cancer
Nolan-Stevaux, Olivier, Li, Cong, Liang, Lingming, Zhan, Jinghui, Estrada, Juan, Osgood, Tao, Li, Fei, Zhang, Hanzhi, Case, Ryan, Murawsky, Christopher M, Estes, Bram, Moore, Gregory L, Bernett, Matthew J, Muchhal, Umesh, Desjarlais, John R, Staley, Binnaz K, Stevens, Jennitte, Cooke, Keegan S, Aeffner, Famke, Thomas, Oliver, Stieglmaier, Julia, Lee, Jae-Lyun, Coxon, Angela, Bailis, Julie M
Published in Cancer discovery (12.01.2024)
Published in Cancer discovery (12.01.2024)
Get full text
Journal Article
OncoVEX mGM-CSF expands tumor antigen-specific CD8+ T-cell response in preclinical models
Estrada, Juan, Zhan, Jinghui, Mitchell, Petia, Werner, Jonathan, Beltran, Pedro J, DeVoss, Jason, Qing, Jing, Cooke, Keegan S
Published in Journal for immunotherapy of cancer (01.05.2023)
Published in Journal for immunotherapy of cancer (01.05.2023)
Get full text
Journal Article
Antigen-Specific Cytolysis by Neutrophils and NK Cells Expressing Chimeric Immune Receptors Bearing {zeta} or {gamma} Signaling Domains
Roberts, Margo R, Cooke, Keegan S, Tran, Annie-Chen, Smith, Kent A, Lin, Wei Yu, Wang, Martin, Dull, Thomas J, Farson, Deborah, Zsebo, Krisztina M, Finer, Mitchell H
Published in The Journal of immunology (1950) (01.07.1998)
Get full text
Published in The Journal of immunology (1950) (01.07.1998)
Journal Article
Validation and Preclinical Correlation of a New Sandwich ELISA for Measuring Murine Hepcidin
Hod, Eldad A., Francis, Richard O., Spitalnik, Steven L., Winters, Aaron, Cooke, Keegan S, Sasu, Barbra J
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
Get full text
Journal Article
Distinct Roles For Hepcidin and Interleukin 6 In The Recovery From Anemia Following Administration Of Heat-Killed Brucella Abortus
Gardenghi, Sara, Renaud, Thomas M., Meloni, Alessandra, Casu, Carla, Crielaard, Bart J., Bystrom, Laura M., Greenberg, Noa, Sasu, Barbra J., Cooke, Keegan S., Rivella, Stefano
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
Get full text
Journal Article
Investigating the Role of Cytokines and Hepcidin in Anemia of Inflammation
Gardenghi, Sara, Renaud, Thomas M., Meloni, Alessandra, Ramos, Pedro, Casu, Carla, Cooke, Keegan S, Sasu, Barbra J, Giardina, Patricia, Grady, Robert W, Rivella, Stefano
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
Get full text
Journal Article
Fully Human Anti-Hepcidin Antibodies Mobilize Iron and Treat Inflammatory Anemia in a Mouse Model
Cooke, Keegan S, Augustic, Adrienne, Sloan, Jeanne, Tran, Linh, Arvedson, Tara L, Juan, Todd, Sasu, Barbra J
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
Get full text
Journal Article
Antigen-specific cytolysis by neutrophils and NK cells expressing chimeric immune receptors bearing zeta or gamma signaling domains
Roberts, M R, Cooke, K S, Tran, A C, Smith, K A, Lin, W Y, Wang, M, Dull, T J, Farson, D, Zsebo, K M, Finer, M H
Published in The Journal of immunology (1950) (01.07.1998)
Published in The Journal of immunology (1950) (01.07.1998)
Get full text
Journal Article
Use of oncolytic viruses for treatment of cancer
MEISEN WALTER HANS, TINBERG CHRISTINE ELAINE, COOKE KEEGAN, DEVOSS JASON JAMES, MOESTA ACHIM KLAUS
Year of Publication 24.09.2021
Get full text
Year of Publication 24.09.2021
Patent
Use of oncolytic viruses for the treatment of cancer
COOKE, KEEGAN, MOESTA, ACHIM KLAUS, MEISEN, WALTER HANS, DEVOSS, JASON J, TINBERG, CHRISTINE ELAINE
Year of Publication 01.01.2021
Get full text
Year of Publication 01.01.2021
Patent
Hepcidin, hepcidin antagonists and methods of use
COOKE, KEEGAN, LEE, KI-JEONG, BI, XIAO-JUAN, WINTERS, AARON, HANIU, MITSURU, SHENG, ZEQI, SASU, BARBRA, ARVEDSON, TARA, BOONE, THOMAS CHARLES
Year of Publication 16.02.2013
Get full text
Year of Publication 16.02.2013
Patent