Communication breaks-Down: from neurodevelopment defects to cognitive disabilities in Down syndrome
Contestabile, Andrea, Benfenati, Fabio, Gasparini, Laura
Published in Progress in neurobiology (01.05.2010)
Published in Progress in neurobiology (01.05.2010)
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Journal Article
Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome
Parrini, Martina, Ghezzi, Diego, Deidda, Gabriele, Medrihan, Lucian, Castroflorio, Enrico, Alberti, Micol, Baldelli, Pietro, Cancedda, Laura, Contestabile, Andrea
Published in Scientific reports (04.12.2017)
Published in Scientific reports (04.12.2017)
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Design, Synthesis, In Vitro and In Vivo Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down Syndrome
Borgogno, Marco, Savardi, Annalisa, Manigrasso, Jacopo, Turci, Alessandra, Portioli, Corinne, Ottonello, Giuliana, Bertozzi, Sine Mandrup, Armirotti, Andrea, Contestabile, Andrea, Cancedda, Laura, De Vivo, Marco
Published in Journal of medicinal chemistry (22.07.2021)
Published in Journal of medicinal chemistry (22.07.2021)
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Journal Article
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice
Prakasam, Ramachandran, Bonadiman, Angela, Andreotti, Roberta, Zuccaro, Emanuela, Dalfovo, Davide, Marchioretti, Caterina, Tripathy, Debasmita, Petris, Gianluca, Anderson, Eric N., Migazzi, Alice, Tosatto, Laura, Cereseto, Anna, Battaglioli, Elena, Sorarù, Gianni, Lim, Wooi Fang, Rinaldi, Carlo, Sambataro, Fabio, Pourshafie, Naemeh, Grunseich, Christopher, Romanel, Alessandro, Pandey, Udai Bhan, Contestabile, Andrea, Ronzitti, Giuseppe, Basso, Manuela, Pennuto, Maria
Published in Nature communications (06.02.2023)
Published in Nature communications (06.02.2023)
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Journal Article
Non-hyperpolarizing GABAB receptor activation regulates neuronal migration and neurite growth and specification by cAMP/LKB1
Bony, Guillaume, Szczurkowska, Joanna, Tamagno, Ilaria, Shelly, Maya, Contestabile, Andrea, Cancedda, Laura
Published in Nature communications (30.04.2013)
Published in Nature communications (30.04.2013)
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Journal Article
A light-gated potassium channel for sustained neuronal inhibition
Alberio, Laura, Locarno, Andrea, Saponaro, Andrea, Romano, Edoardo, Bercier, Valérie, Albadri, Shahad, Simeoni, Federica, Moleri, Silvia, Pelucchi, Silvia, Porro, Alessandro, Marcello, Elena, Barsotti, Noemi, Kukovetz, Kerri, Boender, Arjen J., Contestabile, Andrea, Luo, Shizhen, Moutal, Aubin, Ji, Yingshi, Romani, Giulia, Beltrame, Monica, Del Bene, Filippo, Di Luca, Monica, Khanna, Rajesh, Colecraft, Henry M., Pasqualetti, Massimo, Thiel, Gerhard, Tonini, Raffaella, Moroni, Anna
Published in Nature methods (01.11.2018)
Published in Nature methods (01.11.2018)
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Journal Article
Gene Editing Preserves Visual Functions in a Mouse Model of Retinal Degeneration
Vagni, Paola, Perlini, Laura E., Chenais, Naïg A. L., Marchetti, Tommaso, Parrini, Martina, Contestabile, Andrea, Cancedda, Laura, Ghezzi, Diego
Published in Frontiers in neuroscience (10.09.2019)
Published in Frontiers in neuroscience (10.09.2019)
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Journal Article
Discovery of a Small Molecule Drug Candidate for Selective NKCC1 Inhibition in Brain Disorders
Savardi, Annalisa, Borgogno, Marco, Narducci, Roberto, La Sala, Giuseppina, Ortega, Jose Antonio, Summa, Maria, Armirotti, Andrea, Bertorelli, Rosalia, Contestabile, Andrea, De Vivo, Marco, Cancedda, Laura
Published in Chem (06.08.2020)
Published in Chem (06.08.2020)
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Journal Article
Alternative Splicing of P/Q-Type Ca2+ Channels Shapes Presynaptic Plasticity
Thalhammer, Agnes, Contestabile, Andrea, Ermolyuk, Yaroslav S., Ng, Teclise, Volynski, Kirill E., Soong, Tuck Wah, Goda, Yukiko, Cingolani, Lorenzo A.
Published in Cell reports (Cambridge) (11.07.2017)
Published in Cell reports (Cambridge) (11.07.2017)
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Journal Article
Cell Cycle Elongation Impairs Proliferation of Cerebellar Granule Cell Precursors in the Ts65Dn Mouse, an Animal Model for Down Syndrome
Contestabile, Andrea, Fila, Tatiana, Bartesaghi, Renata, Ciani, Elisabetta
Published in Brain pathology (Zurich, Switzerland) (01.04.2009)
Published in Brain pathology (Zurich, Switzerland) (01.04.2009)
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EARLY-IN-LIFE INTERVENTIONS TARGETING NKCC1 RESCUE THE ALTERED GABAERGIC SIGNALING AND THE EPILEPTIC AND LOCOMOTOR DEFICITS IN THE ADULT DS MICE
Colombi, Ilaria, Ziogas, Ilias, Fumagalli, Amos, Parrini, Martina, Savardi, Annalisa, Alberti, Micol, Contestabile, Andrea, Cancedda, Laura
Published in IBRO neuroscience reports (01.10.2023)
Published in IBRO neuroscience reports (01.10.2023)
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Journal Article
Heterogeneous subpopulations of GABAAR-responding neurons coexist across neuronal network scales and developmental stages in health and disease
Colombi, Ilaria, Rastogi, Mohit, Parrini, Martina, Alberti, Micol, Potenzieri, Alberto, Chellali, Mariam Marie, Rosati, Silvia, Chiappalone, Michela, Nanni, Marina, Contestabile, Andrea, Cancedda, Laura
Published in iScience (19.04.2024)
Published in iScience (19.04.2024)
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Journal Article
Alternative Splicing of P/Q-Type Ca 2+ Channels Shapes Presynaptic Plasticity
Thalhammer, Agnes, Contestabile, Andrea, Ermolyuk, Yaroslav S, Ng, Teclise, Volynski, Kirill E, Soong, Tuck Wah, Goda, Yukiko, Cingolani, Lorenzo A
Published in Cell reports (Cambridge) (01.07.2017)
Published in Cell reports (Cambridge) (01.07.2017)
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Journal Article
Brain Nitric Oxide and Its Dual Role in Neurodegeneration / Neuroprotection: Understanding Molecular Mechanisms to Devise Drug Approaches
Contestabile, Antonio, Monti, Barbara, Contestabile, Andrea, Ciani, Elisabetta
Published in Current medicinal chemistry (01.10.2003)
Published in Current medicinal chemistry (01.10.2003)
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Journal Article
Both Schwann cell and axonal defects cause motor peripheral neuropathy in Ebf2 −/− mice
Giacomini, Caterina, La Padula, Veronica, Schenone, Angelo, Leandri, Massimo, Contestabile, Andrea, Moruzzo, Diego, Goutebroze, Laurence, Consalez, G. Giacomo, Benfenati, Fabio, Corradi, Anna
Published in Neurobiology of disease (01.04.2011)
Published in Neurobiology of disease (01.04.2011)
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Fluorescence resonance energy transfer detection of synaptophysin I and vesicle-associated membrane protein 2 interactions during exocytosis from single live synapses
Pennuto, Maria, Dunlap, David, Contestabile, Andrea, Benfenati, Fabio, Valtorta, Flavia
Published in Molecular biology of the cell (01.08.2002)
Published in Molecular biology of the cell (01.08.2002)
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Journal Article
The GABAergic Hypothesis for Cognitive Disabilities in Down Syndrome
Contestabile, Andrea, Magara, Salvatore, Cancedda, Laura
Published in Frontiers in cellular neuroscience (07.03.2017)
Published in Frontiers in cellular neuroscience (07.03.2017)
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