Consensus molecular subtype 4 (CMS4)-targeted therapy in primary colon cancer: A proof-of-concept study
Peters, Niek A., Constantinides, Alexander, Ubink, Inge, van Kuik, Joyce, Bloemendal, Haiko J., van Dodewaard, Joyce M., Brink, Menno A., Schwartz, Thijs P., Lolkema, Martijn P.J.K., Lacle, Miangela M., Moons, Leon M., Geesing, Joost, van Grevenstein, Wilhelmina M.U., Roodhart, Jeanine M. L., Koopman, Miriam, Elias, Sjoerd G., Borel Rinkes, Inne H.M., Kranenburg, Onno
Published in Frontiers in oncology (06.09.2022)
Published in Frontiers in oncology (06.09.2022)
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Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC)
Rovers, Koen P, Lurvink, Robin J, Wassenaar, Emma CE, Kootstra, Thomas JM, Scholten, Harm J, Tajzai, Rudaba, Deenen, Maarten J, Nederend, Joost, Lahaye, Max J, Huysentruyt, Clément JR, van ’t Erve, Iris, Fijneman, Remond JA, Constantinides, Alexander, Kranenburg, Onno, Los, Maartje, Thijs, Anna MJ, Creemers, Geert-Jan M, Burger, Jacobus WA, Wiezer, Marinus J, Boerma, Djamila, Nienhuijs, Simon W, de Hingh, Ignace HJT
Published in BMJ open (01.07.2019)
Published in BMJ open (01.07.2019)
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Journal Article
Detection of tumor‐derived cell‐free DNA from colorectal cancer peritoneal metastases in plasma and peritoneal fluid
van't Erve, Iris, Rovers, Koen P, Constantinides, Alexander, Bolhuis, Karen, Wassenaar, Emma CE, Lurvink, Robin J, Huysentruyt, Clément J, Snaebjornsson, Petur, Boerma, Djamila, Broek, Daan, Buffart, Tineke E, Lahaye, Max J, Aalbers, Arend GJ, Kok, Niels FM, Meijer, Gerrit A, Punt, Cornelis JA, Kranenburg, Onno, Hingh, Ignace HJT, Fijneman, Remond JA
Published in The journal of pathology. Clinical research (01.05.2021)
Published in The journal of pathology. Clinical research (01.05.2021)
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Journal Article
Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity
Laoukili, Jamila, Constantinides, Alexander, Wassenaar, Emma C. E., Elias, Sjoerd G., Raats, Danielle A. E., van Schelven, Susanne J., van Wettum, Jonathan, Volckmann, Richard, Koster, Jan, Huitema, Alwin D. R., Nienhuijs, Simon W., de Hingh, Ignace H. J. T., Wiezer, René J., van Grevenstein, Helma M. U., Rinkes, Inne H. M. Borel, Boerma, Djamila, Kranenburg, Onno
Published in British journal of cancer (01.06.2022)
Published in British journal of cancer (01.06.2022)
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Palliative systemic therapy and oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy in patients with unresectable colorectal peritoneal metastases in a phase II trial (CRC-PIPAC-II)
Van De Vlasakker, Vincent, Rauwerdink, Paulien, Rovers, Koen P., Wassenaar, Emma C.E., Deenen, Maarten J., Nederend, Joost, Huysentruyt, Clément J.R., Fijneman, Remond J.A., van der Hoeven, Erik J.R.J., Raicu, Mihaela M., Constantinides, Alexander, Kranenburg, Onno, Los, Maartje, Creemers, Geert-Jan M., Burger, Pim W.A., Wiezer, René J., Nienhuijs, Simon W., Lurvink, Robin J., Boerma, Djamila, de Hingh, Ignace H.J.T.
Published in European journal of surgical oncology (01.02.2023)
Published in European journal of surgical oncology (01.02.2023)
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Journal Article
Abstract 708: Limited release of circulating tumor DNA into the systemic circulation by peritoneal metastases from colorectal cancer
van 't Erve, Iris, Rovers, Koen P., Constantinides, Alexander, Bolhuis, Karen, Wassenaar, Emma C., Lurvink, Robin J., Huysentruyt, Clément J., Snaebjornsson, Petur, van den Broek, Daan, Buffart, Tineke E., Kok, Niels F., Meijer, Gerrit A., Punt, Cornelis J., Kranenburg, Onno, de Hingh, Ignace H., Fijneman, Remond J.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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First-line palliative systemic therapy alternated with oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy for unresectable colorectal peritoneal metastases: A single-arm phase II trial (CRC-PIPAC-II)
Rauwerdink, Paulien, van de Vlasakker, Vincent C.J., Wassenaar, Emma C.E., Rovers, Koen P., Los, Maartje, Herbschleb, Karin H., Creemers, Geert-Jan M., Thijs, Annemarie M.J., Raicu, Mihaela G., Huysentruyt, Clément J.R., van der Hoeven, Erik J.R.J., Nederend, Joost, Peeters, Rifka Y.M., Deenen, Maarten J., Elias, Sjoerd G., Fijneman, Remond J.A., Constantinides, Alexander, Kranenburg, Onno, Burger, Pim W.A., Nienhuijs, Simon W., Wiezer, René J., Lurvink, Robin J., de Hingh, Ignace H.J.T., Boerma, Djamila
Published in European journal of surgical oncology (01.09.2024)
Published in European journal of surgical oncology (01.09.2024)
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Concomitant intraperitoneal and systemic chemotherapy for extensive peritoneal metastases of colorectal origin: protocol of the multicentre, open-label, phase I, dose-escalation INTERACT trial
de Boer, Nadine Leonie, Brandt-Kerkhof, Alexandra R M, Madsen, Eva V E, Diepeveen, Marjolein, van Meerten, Esther, van Eerden, Ruben A G, de Man, Femke M, Bouamar, Rachida, Koolen, Stijn L W, de Hingh, Ignace H J T, Bakkers, Checca, Rovers, Koen P, Creemers, Geert-Jan M, Deenen, Maarten J, Kranenburg, Onno W, Constantinides, Alexander, Mathijssen, Ron H J, Verhoef, Cornelis, Burger, Jacobus W A
Published in BMJ open (08.12.2019)
Published in BMJ open (08.12.2019)
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Journal Article
First-line palliative systemic therapy alternated with electrostatic pressurised intraperitoneal aerosol chemotherapy (oxaliplatin) for isolated unresectable colorectal peritoneal metastases: protocol of a multicentre, single-arm, phase II study (CRC-PIPAC-II)
Lurvink, Robin J., Rauwerdink, Paulien, Rovers, Koen P., Wassenaar, Emma C.E., Deenen, Maarten J., Nederend, Joost, Huysentruyt, Clément J.R., van 't Erve, Iris, Fijneman, Remond J.A., van der Hoeven, Erik J.R.J., Seldenrijk, Cornelis A., Constantinides, Alexander, Kranenburg, Onno, Los, Maartje, Herbschleb, Karin H., Thijs, Anna M.J., Creemers, Geert-Jan M., Burger, Jacobus W.A., Wiezer, Marinus J., Nienhuijs, Simon W., Boerma, Djamila, de Hingh, Ignace H.J.T.
Published in BMJ open (30.03.2021)
Published in BMJ open (30.03.2021)
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Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases
Bootsma, Sanne, Dings, Mark P.G., Kesselaar, Job, Helderman, Roxan F.C.P.A., van Megesen, Kyah, Constantinides, Alexander, Moreno, Leandro Ferreira, Stelloo, Ellen, Scutigliani, Enzo M., Bokan, Bella, Torang, Arezo, van Hooff, Sander R., Zwijnenburg, Danny A., Wouters, Valérie M., van de Vlasakker, Vincent C.J., Galanos, Laskarina J.K., Nijman, Lisanne E., Logiantara, Adrian, Veenstra, Veronique L., Schlingemann, Sophie, van Piggelen, Sterre, van der Wel, Nicole, Krawczyk, Przemek M., Platteeuw, Johannes J., Tuynman, Jurriaan B., de Hingh, Ignace H., Klomp, Jan P.G., Oubrie, Arthur, Snaebjornsson, Petur, Medema, Jan Paul, Oei, Arlene L., Kranenburg, Onno, Elbers, Clara C., Lenos, Kristiaan J., Vermeulen, Louis, Bijlsma, Maarten F.
Published in Cell reports. Medicine (21.05.2024)
Published in Cell reports. Medicine (21.05.2024)
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Plasma Cholesteryl Ester Transfer, But Not Cholesterol Esterification, Is Related to Lipoprotein-Associated Phospholipase A2: Possible Contribution to an Atherogenic Lipoprotein Profile
Dullaart, Robin P. F, Constantinides, Alexander, Perton, Frank G, van Leeuwen, Jeroen J. J, van Pelt, Joost L, de Vries, Rindert, van Tol, Arie
Published in The journal of clinical endocrinology and metabolism (01.04.2011)
Published in The journal of clinical endocrinology and metabolism (01.04.2011)
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Journal Article
Plasma Lp‐PLA 2 mass and apoB‐lipoproteins that carry Lp‐PLA 2 decrease after sodium
Constantinides, Alexander, Kerstens, Michiel N., Dikkeschei, Bert D., van Pelt, L. Joost, Tellis, Constantinos C., Tselepis, Alexandros D., Dullaart, Robin P. F.
Published in European journal of clinical investigation (01.11.2012)
Published in European journal of clinical investigation (01.11.2012)
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Journal Article
Plasma Lp-PLA2 mass and apoB-lipoproteins that carry Lp-PLA2 decrease after sodium
Constantinides, Alexander, Kerstens, Michiel N., Dikkeschei, Bert D., van Pelt, L. Joost, Tellis, Constantinos C., Tselepis, Alexandros D., Dullaart, Robin P. F.
Published in European journal of clinical investigation (01.11.2012)
Published in European journal of clinical investigation (01.11.2012)
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Journal Article
Carotid intima media thickness is associated with plasma lipoprotein-associated phospholipase A2 mass in nondiabetic subjects but not in patients with type 2 diabetes: IMT LP-PLA2 RELATIONS IN (NON) DIABETIC SUBJECTS
Constantinides, Alexander, van Pelt, L. Joost, van Leeuwen, Jeroen J. J., de Vries, Rindert, Tio, René A., van der Horst, Iwan C. C., Sluiter, Wim J., Dullaart, Robin P. F.
Published in European journal of clinical investigation (01.08.2011)
Published in European journal of clinical investigation (01.08.2011)
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Journal Article
Simvastatin but not bezafibrate decreases plasma lipoprotein-associated phospholipase A2 mass in type 2 diabetes mellitus: Relevance of high sensitive C-reactive protein, lipoprotein profile and low-density lipoprotein (LDL) electronegativity
Constantinides, Alexander, de Vries, Rindert, van Leeuwen, Jeroen J.J, Gautier, Thomas, van Pelt, L. Joost, Tselepis, Alexandros D, Lagrost, Laurent, Dullaart, Robin P.F
Published in European journal of internal medicine (01.10.2012)
Published in European journal of internal medicine (01.10.2012)
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Journal Article
Carotid intima media thickness is associated with plasma lipoprotein-associated phospholipase A2 mass in nondiabetic subjects but not in patients with type 2 diabetes
Constantinides, Alexander, van Pelt, L. Joost, van Leeuwen, Jeroen J. J., de Vries, Rindert, Tio, René A., van der Horst, Iwan C. C., Sluiter, Wim J., Dullaart, Robin P. F.
Published in European journal of clinical investigation (01.08.2011)
Published in European journal of clinical investigation (01.08.2011)
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Journal Article
Plasma Lp-PLA(2) mass and apoB-lipoproteins that carry Lp-PLA(2) decrease after sodium
Constantinides, Alexander, Kerstens, Michiel N, Dikkeschei, Bert D, van Pelt, L Joost, Tellis, Constantinos C, Tselepis, Alexandros D, Dullaart, Robin P F
Published in European journal of clinical investigation (01.11.2012)
Published in European journal of clinical investigation (01.11.2012)
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