Metabolism of Chloroform by Cytochrome P450 2E1 Is Required for Induction of Toxicity in the Liver, Kidney, and Nose of Male Mice
Constan, Alexander A., Sprankle, Catherine S., Peters, Jeffrey M., Kedderis, Gregory L., Everitt, Jeffrey I., Wong, Brian A., Gonzalez, Frank L., Butterworth, Byron E.
Published in Toxicology and applied pharmacology (15.10.1999)
Published in Toxicology and applied pharmacology (15.10.1999)
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Journal Article
Physiologically Based Pharmacodynamic Modeling of an Interaction Threshold between Trichloroethylene and 1,1-Dichloroethylene in Fischer 344 Rats
El-Masri, Hisham A., Constan, Alexander A., Ramsdell, Howard S., Yang, Raymond S.H.
Published in Toxicology and applied pharmacology (1996)
Published in Toxicology and applied pharmacology (1996)
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Journal Article
Physiologically based pharmacodynamic modeling of an interaction threshold between trichloroethylene and 1,1-dichloroethylene in fischer 344 rats
El-Masri, Hisham A., Constan, Alexander A., Ramsdell, Howard S., Yang, Raymond S.H.
Published in Toxicology and applied pharmacology (01.11.1996)
Published in Toxicology and applied pharmacology (01.11.1996)
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Journal Article
Long-term mutagenicity studies with chloroform and dimethylnitrosamine in female lacI transgenic B6C3F1 mice
Butterworth, Byron E., Templin, Michael V., Constan, Alexander A., Sprankle, Catherine S., Wong, Brian A., Pluta, Linda J., Everitt, Jeffrey I., Recio, Leslie
Published in Environmental and molecular mutagenesis (1998)
Published in Environmental and molecular mutagenesis (1998)
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Journal Article
The application of physiologically based pharmacokinetic/ pharmacodynamic (PBPK/PD) modeling for exploring risk assessment approaches of chemical mixtures
Yang, Raymond S.H., El-Masri, Hisham A., Thomas, Russell S., Constan, Alexander A., Tessari, John D.
Published in Toxicology letters (01.09.1995)
Published in Toxicology letters (01.09.1995)
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Conference Proceeding
The use of physiologically-based pharmacokinetic/ pharmacodynamic dosimetry models for chemical mixtures
Yang, Raymond S.H., El-Masri, Hisham A., Thomas, Rüssel S., Constan, Alexander A.
Published in Toxicology Letters (01.12.1995)
Published in Toxicology Letters (01.12.1995)
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Conference Proceeding
Incorporating Monte Carlo Simulation into Physiologically Based Pharmacokinetic Models Using Advanced Continuous Simulation Language (ACSL): A Computational Method
THOMAS, RUSSELL S., LYTLE, WILLIAM E., KEEFE, THOMAS J., CONSTAN, ALEXANDER A., YANG, RAYMOND S. H.
Published in Toxicological sciences (1996)
Published in Toxicological sciences (1996)
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Physiologically based pharmacokinetic/pharmacodynamic modeling of the toxicologic interaction between carbon tetrachloride and Kepone
el-Masri, H A, Thomas, R S, Sabados, G R, Phillips, J K, Constan, A A, Benjamin, S A, Andersen, M E, Mehendale, H M, Yang, R S
Published in Archives of toxicology (1996)
Published in Archives of toxicology (1996)
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Long-term mutagenicity studies with chloroform and dimethylnitrosamine in femalelacI transgenic B6C3F1 mice
Butterworth, Byron E., Templin, Michael V., Constan, Alexander A., Sprankle, Catherine S., Wong, Brian A., Pluta, Linda J., Everitt, Jeffrey I., Recio, Leslie
Published in Environmental and molecular mutagenesis (1998)
Published in Environmental and molecular mutagenesis (1998)
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Journal Article
Methods of treatment using an EP2 selective receptor agonist
MACLEAN DAVID B, KESHARY PRAKASH, CONSTAN ALEXANDER A, PARALKAR VISHWAS M, ROMAN DOINA, THOMPSON DAVID D, WRIGHT TIMOTHY M
Year of Publication 15.09.2005
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Year of Publication 15.09.2005
Patent
Incorporating Monte Carlo Simulation into Physiologically Based Pharmacokinetic Models Using Advanced Continuous Simulation Language (ACSL): A Computational Method
Thomas, Russell S., Lytle, William E., Keefe, Thomas J., Constan, Alexander A., Yang, Raymond S.H.
Published in Fundamental and applied toxicology (01.05.1996)
Published in Fundamental and applied toxicology (01.05.1996)
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