Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
Conos, Stephanie A., Chen, Kaiwen W., De Nardo, Dominic, Hara, Hideki, Whitehead, Lachlan, Núñez, Gabriel, Masters, Seth L., Murphy, James M., Schroder, Kate, Vaux, David L., Lawlor, Kate E., Lindqvist, Lisa M., Vince, James E.
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2017)
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Journal Article
XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation
Lawlor, Kate E., Feltham, Rebecca, Yabal, Monica, Conos, Stephanie A., Chen, Kaiwen W., Ziehe, Stephanie, Graß, Carina, Zhan, Yifan, Nguyen, Tan A., Hall, Cathrine, Vince, Angelina J., Chatfield, Simon M., D’Silva, Damian B., Pang, Kenneth C., Schroder, Kate, Silke, John, Vaux, David L., Jost, Philipp J., Vince, James E.
Published in Cell reports (Cambridge) (18.07.2017)
Published in Cell reports (Cambridge) (18.07.2017)
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Journal Article
Targeting RIP Kinases in Chronic Inflammatory Disease
Speir, Mary, Djajawi, Tirta M, Conos, Stephanie A, Tye, Hazel, Lawlor, Kate E
Published in Biomolecules (Basel, Switzerland) (28.04.2021)
Published in Biomolecules (Basel, Switzerland) (28.04.2021)
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Journal Article
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
Simpson, Daniel S., Pang, Jiyi, Weir, Ashley, Kong, Isabella Y., Fritsch, Melanie, Rashidi, Maryam, Cooney, James P., Davidson, Kathryn C., Speir, Mary, Djajawi, Tirta M., Hughes, Sebastian, Mackiewicz, Liana, Dayton, Merle, Anderton, Holly, Doerflinger, Marcel, Deng, Yexuan, Huang, Allan Shuai, Conos, Stephanie A., Tye, Hazel, Chow, Seong H., Rahman, Arfatur, Norton, Raymond S., Naderer, Thomas, Nicholson, Sandra E., Burgio, Gaetan, Man, Si Ming, Groom, Joanna R., Herold, Marco J., Hawkins, Edwin D., Lawlor, Kate E., Strasser, Andreas, Silke, John, Pellegrini, Marc, Kashkar, Hamid, Feltham, Rebecca, Vince, James E.
Published in Immunity (Cambridge, Mass.) (08.03.2022)
Published in Immunity (Cambridge, Mass.) (08.03.2022)
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Journal Article
Caspase‐8‐driven apoptotic and pyroptotic crosstalk causes cell death and IL‐1β release in X‐linked inhibitor of apoptosis (XIAP) deficiency
Hughes, Sebastian A, Lin, Meng, Weir, Ashley, Huang, Bing, Xiong, Liya, Chua, Ngee Kiat, Pang, Jiyi, Santavanond, Jascinta P, Tixeira, Rochelle, Doerflinger, Marcel, Deng, Yexuan, Yu, Chien‐Hsiung, Silke, Natasha, Conos, Stephanie A, Frank, Daniel, Simpson, Daniel S, Murphy, James M, Lawlor, Kate E, Pearson, Jaclyn S, Silke, John, Pellegrini, Marc, Herold, Marco J, Poon, Ivan K H, Masters, Seth L, Li, Mingsong, Tang, Qin, Zhang, Yuxia, Rashidi, Maryam, Geng, Lanlan, Vince, James E
Published in The EMBO journal (01.03.2023)
Published in The EMBO journal (01.03.2023)
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Journal Article
A1 is induced by pathogen ligands to limit myeloid cell death and NLRP3 inflammasome activation
Speir, Mary, Tye, Hazel, Gottschalk, Timothy A, Simpson, Daniel S, Djajawi, Tirta M, Deo, Pankaj, Ambrose, Rebecca L, Conos, Stephanie A, Emery, Jack, Abraham, Gilu, Pascoe, Ashlyn, Hughes, Sebastian A, Weir, Ashley, Hawkins, Edwin D, Kong, Isabella, Herold, Marco J, Pearson, Jaclyn S, Lalaoui, Najoua, Naderer, Thomas, Vince, James E, Lawlor, Kate E
Published in EMBO reports (06.11.2023)
Published in EMBO reports (06.11.2023)
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Journal Article
A circRNA from SEPALLATA3 regulates splicing of its cognate mRNA through R-loop formation
Conn, Vanessa M., Hugouvieux, Véronique, Nayak, Aditya, Conos, Stephanie A., Capovilla, Giovanna, Cildir, Gökhan, Jourdain, Agnès, Tergaonkar, Vinay, Schmid, Markus, Zubieta, Chloe, Conn, Simon J.
Published in Nature plants (18.04.2017)
Published in Nature plants (18.04.2017)
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Journal Article
Divergent roles of RIPK3 and MLKL in high-fat diet–induced obesity and MAFLD in mice
Tye, Hazel, Conos, Stephanie A, Djajawi, Tirta M, Gottschalk, Timothy A, Abdoulkader, Nasteho, Kong, Isabella Y, Kammoun, Helene L, Narayana, Vinod K, Kratina, Tobias, Speir, Mary, Emery, Jack, Simpson, Daniel S, Hall, Cathrine, Vince, Angelina J, Russo, Sophia, Crawley, Rhiannan, Rashidi, Maryam, Hildebrand, Joanne M, Murphy, James M, Whitehead, Lachlan, De Souza, David P, Masters, Seth L, Samson, Andre L, Lalaoui, Najoua, Hawkins, Edwin D, Murphy, Andrew J, Vince, James E, Lawlor, Kate E
Published in Life science alliance (01.01.2025)
Published in Life science alliance (01.01.2025)
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