An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus
Snijder, Joost, Ortego, Michael S., Weidle, Connor, Stuart, Andrew B., Gray, Matthew D., McElrath, M. Juliana, Pancera, Marie, Veesler, David, McGuire, Andrew T.
Published in Immunity (Cambridge, Mass.) (17.04.2018)
Published in Immunity (Cambridge, Mass.) (17.04.2018)
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Journal Article
HIV-1 VRC01 Germline-Targeting Immunogens Select Distinct Epitope-Specific B Cell Receptors
Lin, Yu-Ru, Parks, K. Rachael, Weidle, Connor, Naidu, Anika S., Khechaduri, Arineh, Riker, Andrew O., Takushi, Brittany, Chun, Jung-Ho, Borst, Andrew J., Veesler, David, Stuart, Andrew, Agrawal, Parul, Gray, Matthew, Pancera, Marie, Huang, Po-Ssu, Stamatatos, Leonidas
Published in Immunity (Cambridge, Mass.) (13.10.2020)
Published in Immunity (Cambridge, Mass.) (13.10.2020)
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Journal Article
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core
Borst, Andrew J, Weidle, Connor E, Gray, Matthew D, Frenz, Brandon, Snijder, Joost, Joyce, M Gordon, Georgiev, Ivelin S, Stewart-Jones, Guillaume Be, Kwong, Peter D, McGuire, Andrew T, DiMaio, Frank, Stamatatos, Leonidas, Pancera, Marie, Veesler, David
Published in eLife (07.11.2018)
Published in eLife (07.11.2018)
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Journal Article
Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization
Parks, K. Rachael, MacCamy, Anna J., Trichka, Josephine, Gray, Matthew, Weidle, Connor, Borst, Andrew J., Khechaduri, Arineh, Takushi, Brittany, Agrawal, Parul, Guenaga, Javier, Wyatt, Richard T., Coler, Rhea, Seaman, Michael, LaBranche, Celia, Montefiori, David C., Veesler, David, Pancera, Marie, McGuire, Andrew, Stamatatos, Leonidas
Published in Cell reports (Cambridge) (03.12.2019)
Published in Cell reports (Cambridge) (03.12.2019)
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Protective antibodies against human parainfluenza virus type 3 infection
Boonyaratanakornkit, Jim, Singh, Suruchi, Weidle, Connor, Rodarte, Justas, Bakthavatsalam, Ramasamy, Perkins, Jonathan, Stewart-Jones, Guillaume B E, Kwong, Peter D, McGuire, Andrew T, Pancera, Marie, Taylor, Justin J
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies
Seydoux, Emilie, Wan, Yu-Hsin, Feng, Junli, Wall, Abigail, Aljedani, Safia, Homad, Leah J., MacCamy, Anna J., Weidle, Connor, Gray, Matthew D., Brumage, Lauren, Taylor, Justin J., Pancera, Marie, Stamatatos, Leonidas, McGuire, Andrew T.
Published in Cell reports (Cambridge) (04.05.2021)
Published in Cell reports (Cambridge) (04.05.2021)
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Journal Article
Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
Kisalu, Neville K, Idris, Azza H, Weidle, Connor, Flores-Garcia, Yevel, Flynn, Barbara J, Sack, Brandon K, Murphy, Sean, Schön, Arne, Freire, Ernesto, Francica, Joseph R, Miller, Alex B, Gregory, Jason, March, Sandra, Liao, Hua-Xin, Haynes, Barton F, Wiehe, Kevin, Trama, Ashley M, Saunders, Kevin O, Gladden, Morgan A, Monroe, Anthony, Bonsignori, Mattia, Kanekiyo, Masaru, Wheatley, Adam K, McDermott, Adrian B, Farney, S Katie, Chuang, Gwo-Yu, Zhang, Baoshan, Kc, Natasha, Chakravarty, Sumana, Kwong, Peter D, Sinnis, Photini, Bhatia, Sangeeta N, Kappe, Stefan H I, Sim, B Kim Lee, Hoffman, Stephen L, Zavala, Fidel, Pancera, Marie, Seder, Robert A
Published in Nature medicine (2019)
Published in Nature medicine (2019)
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Journal Article
Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain
Gray, Matthew D, Feng, Junli, Weidle, Connor E, Cohen, Kristen W, Ballweber-Fleming, Lamar, MacCamy, Anna J, Huynh, Crystal N, Trichka, Josephine J, Montefiori, David, Ferrari, Guido, Pancera, Marie, McElrath, M Juliana, Stamatatos, Leonidas
Published in Science advances (06.05.2022)
Published in Science advances (06.05.2022)
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Journal Article
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
Kisalu, Neville K, Idris, Azza H, Weidle, Connor, Flores-Garcia, Yevel, Flynn, Barbara J, Sack, Brandon K, Murphy, Sean, Schön, Arne, Freire, Ernesto, Francica, Joseph R, Miller, Alex B, Gregory, Jason, March, Sandra, Liao, Hua-Xin, Haynes, Barton F, Wiehe, Kevin, Trama, Ashley M, Saunders, Kevin O, Gladden, Morgan A, Monroe, Anthony, Bonsignori, Mattia, Kanekiyo, Masaru, Wheatley, Adam K, McDermott, Adrian B, Farney, S Katie, Chuang, Gwo-Yu, Zhang, Baoshan, Kc, Natasha, Chakravarty, Sumana, Kwong, Peter D, Sinnis, Photini, Bhatia, Sangeeta N, Kappe, Stefan H I, Sim, B Kim Lee, Hoffman, Stephen L, Zavala, Fidel, Pancera, Marie, Seder, Robert A
Published in Nature medicine (01.04.2018)
Published in Nature medicine (01.04.2018)
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Journal Article
De novo design of allosterically switchable protein assemblies
Pillai, Arvind, Idris, Abbas, Philomin, Annika, Weidle, Connor, Skotheim, Rebecca, Leung, Philip J. Y., Broerman, Adam, Demakis, Cullen, Borst, Andrew J., Praetorius, Florian, Baker, David
Published in Nature (London) (22.08.2024)
Published in Nature (London) (22.08.2024)
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Journal Article
Accurate computational design of three-dimensional protein crystals
Li, Zhe, Wang, Shunzhi, Nattermann, Una, Bera, Asim K., Borst, Andrew J., Yaman, Muammer Y., Bick, Matthew J., Yang, Erin C., Sheffler, William, Lee, Byeongdu, Seifert, Soenke, Hura, Greg L., Nguyen, Hannah, Kang, Alex, Dalal, Radhika, Lubner, Joshua M., Hsia, Yang, Haddox, Hugh, Courbet, Alexis, Dowling, Quinton, Miranda, Marcos, Favor, Andrew, Etemadi, Ali, Edman, Natasha I., Yang, Wei, Weidle, Connor, Sankaran, Banumathi, Negahdari, Babak, Ross, Michael B., Ginger, David S., Baker, David
Published in Nature materials (01.12.2023)
Published in Nature materials (01.12.2023)
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Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding
Rodarte, Justas V., Baehr, Carly, Hicks, Dustin, Liban, Tyler L., Weidle, Connor, Rupert, Peter B., Jahan, Rajwana, Wall, Abigail, McGuire, Andrew T., Strong, Roland K., Runyon, Scott, Pravetoni, Marco, Pancera, Marie
Published in Structure (London) (05.01.2023)
Published in Structure (London) (05.01.2023)
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Blueprinting extendable nanomaterials with standardized protein blocks
Huddy, Timothy F., Hsia, Yang, Kibler, Ryan D., Xu, Jinwei, Bethel, Neville, Nagarajan, Deepesh, Redler, Rachel, Leung, Philip J. Y., Weidle, Connor, Courbet, Alexis, Yang, Erin C., Bera, Asim K., Coudray, Nicolas, Calise, S. John, Davila-Hernandez, Fatima A., Han, Hannah L., Carr, Kenneth D., Li, Zhe, McHugh, Ryan, Reggiano, Gabriella, Kang, Alex, Sankaran, Banumathi, Dickinson, Miles S., Coventry, Brian, Brunette, T. J., Liu, Yulai, Dauparas, Justas, Borst, Andrew J., Ekiert, Damian, Kollman, Justin M., Bhabha, Gira, Baker, David
Published in Nature (London) (28.03.2024)
Published in Nature (London) (28.03.2024)
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Journal Article
Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses
Dosenovic, Pia, Pettersson, Anna-Klara, Wall, Abigail, Thientosapol, Eddy S, Feng, Junli, Weidle, Connor, Bhullar, Komal, Kara, Ervin E, Hartweger, Harald, Pai, Joy A, Gray, Matthew D, Parks, K Rachael, Taylor, Justin J, Pancera, Marie, Stamatatos, Leonidas, Nussenzweig, Michel C, McGuire, Andrew T
Published in The Journal of experimental medicine (07.10.2019)
Published in The Journal of experimental medicine (07.10.2019)
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Journal Article
Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes
Bancroft, Tara, DeBuysscher, Blair L, Weidle, Connor, Schwartz, Allison, Wall, Abigail, Gray, Matthew D, Feng, Junli, Steach, Holly R, Fitzpatrick, Kristin S, Gewe, Mesfin M, Skog, Patrick D, Doyle-Cooper, Colleen, Ota, Takayuki, Strong, Roland K, Nemazee, David, Pancera, Marie, Stamatatos, Leonidas, McGuire, Andrew T, Taylor, Justin J
Published in The Journal of experimental medicine (07.10.2019)
Published in The Journal of experimental medicine (07.10.2019)
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Journal Article
Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies
Seydoux, Emilie, Wan, Yu-Hsin, Feng, Junli, Wall, Abigail, Aljedani, Safia, Homad, Leah J., MacCamy, Anna J., Weidle, Connor, Gray, Matthew D., Brumage, Lauren, Taylor, Justin J., Pancera, Marie, Stamatatos, Leonidas, McGuire, Andrew T.
Published in Cell reports (Cambridge) (20.07.2021)
Published in Cell reports (Cambridge) (20.07.2021)
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Journal Article
A human monoclonal antibody prevents malaria infection and defines a new site of vulnerability on Plasmodium falciparum circumsporozoite protein
Kisalu, Neville K., Idris, Azza H., Weidle, Connor, Flores-Garcia, Yevel, Flynn, Barbara J., Sack, Brandon K., Murphy, Sean, Schön, Arne, Freire, Ernesto, Francica, Joseph R., Miller, Alex B., Gregory, Jason, March, Sandra, Liao, Hua-Xin, Haynes, Barton F., Wiehe, Kevin, Trama, Ashley M., Saunders, Kevin O., Gladden, Morgan A., Monroe, Anthony, Bonsignori, Mattia, Kanekiyo, Masaru, Wheatley, Adam K., McDermott, Adrian B., Farney, S. Katie, Chuang, Gwo-Yu, Zhang, Baoshan, Natasha, K C, Chakravarty, Sumana, Kwong, Peter D., Sinnis, Photini, Bhatia, Sangeeta N., Kappe, Stefan H. I., Sim, B. Kim Lee, Hoffman, Stephen L., Zavala, Fidel, Pancera, Marie, Seder, Robert A.
Published in Nature medicine (19.03.2018)
Published in Nature medicine (19.03.2018)
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