Structure-based amelioration of PXR transactivation in a novel series of macrocyclic allosteric inhibitors of HIV-1 integrase
Sivaprakasam, Prasanna, Wang, Zhongyu, Meanwell, Nicholas A., Khan, Javed A., Langley, David R., Johnson, Stephen R., Li, Guo, Pendri, Annapurna, Connolly, Timothy P., Gao, Mian, Camac, Daniel M., Klakouski, Cheryl, Zvyaga, Tatyana, Cianci, Christopher, McAuliffe, Brian, Ding, Bo, Discotto, Linda, Krystal, Mark R., Jenkins, Susan, Peese, Kevin M., Narasimhulu Naidu, B.
Published in Bioorganic & medicinal chemistry letters (15.11.2020)
Published in Bioorganic & medicinal chemistry letters (15.11.2020)
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Phosphonooxymethyl prodrugs of the broad spectrum antifungal azole, ravuconazole: Synthesis and biological properties
UEDA, Yasutsugu, MATISKELLA, John D, VARIA, Sailesh, KNIPE, Jay, MING ZHENG, MATHEW, Marina, MOSURE, Kathy, CLARK, Junius, LAMB, Lucinda, MEDIN, Ivette, QI GAO, HUANG, Stella, GOLIK, Jerzy, CHEN, Chung-Pin, BRONSON, Joanne J, CONNOLLY, Timothy P, HUDYMA, Thomas W, VENKATESH, Srini, DALI, Mandar, KANG, Shin-Hong, BARBOUR, Nancy, TEJWANI, Ravi
Published in Bioorganic & medicinal chemistry letters (03.11.2003)
Published in Bioorganic & medicinal chemistry letters (03.11.2003)
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The discovery and preclinical evaluation of BMS-707035, a potent HIV-1 integrase strand transfer inhibitor
Naidu, B. Narasimhulu, Walker, Michael A., Sorenson, Margaret E., Ueda, Yasutsugu, Matiskella, John D., Connolly, Timothy P., Dicker, Ira B., Lin, Zeyu, Bollini, Sagarika, Terry, Brian J., Higley, Helen, Zheng, Ming, Parker, Dawn D., Wu, Dedong, Adams, Stephen, Krystal, Mark R., Meanwell, Nicholas A.
Published in Bioorganic & medicinal chemistry letters (01.07.2018)
Published in Bioorganic & medicinal chemistry letters (01.07.2018)
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Novel semi-synthetic nocathiacin antibiotics: synthesis and antibacterial activity of bis- and mono- O-alkylated derivatives
Regueiro-Ren, Alicia, Naidu, B.Narasimhulu, Zheng, Xiaofan, Hudyma, Thomas W., Connolly, Timothy P., Matiskella, John D., Zhang, Yunhui, Kim, Oak K., Sorenson, Margaret E., Pucci, Michael, Clark, Junius, Bronson, Joanne J., Ueda, Yasutsugu
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
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Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Attachment 6. Preclinical and Human Pharmacokinetic Profiling of BMS-663749, a Phosphonooxymethyl Prodrug of the HIV-1 Attachment Inhibitor 2-(4-Benzoyl-1-piperazinyl)-1-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoethanone (BMS-488043)
Kadow, John F, Ueda, Yasutsugu, Meanwell, Nicholas A, Connolly, Timothy P, Wang, Tao, Chen, Chung-Pin, Yeung, Kap-Sun, Zhu, Juliang, Bender, John A, Yang, Zhong, Parker, Dawn, Lin, Pin-Fang, Colonno, Richard J, Mathew, Marina, Morgan, Daniel, Zheng, Ming, Chien, Caly, Grasela, Dennis
Published in Journal of medicinal chemistry (08.03.2012)
Published in Journal of medicinal chemistry (08.03.2012)
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A Simple One-Step Conversion of Carboxylic Acids to Esters Using EEDQ
Zacharie, Boulos, Connolly, Timothy P, Penney, Christopher L
Published in Journal of organic chemistry (01.10.1995)
Published in Journal of organic chemistry (01.10.1995)
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Synthesis and antibacterial activity of nocathiacin I analogues
Naidu, B. Narasimhulu, Sorenson, Margaret E., Matiskella, John D., Li, Wenying, Sausker, Justin B., Zhang, Yunhui, Connolly, Timothy P., Lam, Kin S., Bronson, Joanne J., Pucci, Michael J., Yang, Hyekyung, Ueda, Yasutsugu
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
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Nocathiacin I analogues: synthesis, in vitro and in vivo biological activity of novel semi-synthetic thiazolyl peptide antibiotics
Naidu, B. Narasimhulu, Sorenson, Margaret E., Zhang, Yunhui, Kim, Oak K., Matiskella, John D., Wichtowski, John A., Connolly, Timothy P., Li, Wenying, Lam, Kin S., Bronson, Joanne J., Pucci, Michael J., Clark, Junius M., Ueda, Yasutsugu
Published in Bioorganic & medicinal chemistry letters (15.11.2004)
Published in Bioorganic & medicinal chemistry letters (15.11.2004)
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Organic reactions in frozen water: Michael addition of amines and thiols to the dehydroalanine side chain of nocathiacins
Naidu, B.Narasimhulu, Li, Wenying, Sorenson, Margaret E., Connolly, Timothy P., Wichtowski, John A., Zhang, Yunhui, Kim, Oak K., Matiskella, John D., Lam, Kin S., Bronson, Joanne J., Ueda, Yasutsugu
Published in Tetrahedron letters (01.01.2004)
Published in Tetrahedron letters (01.01.2004)
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Synthesis and activity of a C-8 keto pleuromutilin derivative
Springer, Dane M, Sorenson, Margaret E, Huang, Stella, Connolly, Timothy P, Bronson, Joanne J, Matson, James A, Hanson, Ronald L, Brzozowski, David B, LaPorte, Thomas L, Patel, Ramesh N
Published in Bioorganic & medicinal chemistry letters (19.05.2003)
Published in Bioorganic & medicinal chemistry letters (19.05.2003)
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Chemical Conversion of Nocathiacin I to Nocathiacin II and a Lactone Analogue of Glycothiohexide α
Connolly, Timothy P, Regueiro-Ren, Alicia, Leet, John E, Springer, Dane M, Goodrich, Jason, Huang, Xiaohua (Stella), Pucci, Michael J, Clark, Junius M, Bronson, Joanne J, Ueda, Yasutsugu
Published in Journal of natural products (Washington, D.C.) (01.04.2005)
Published in Journal of natural products (Washington, D.C.) (01.04.2005)
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면역조정제로서 유용한 화합물
YEUNG KAP SUN, MULL ERIC, ZHU JULIANG, SCOLA PAUL MICHAEL, HEWAWASAM PIYASENA, XU NINGNING, CONNOLLY TIMOTHY P, MENG ZHAOXING, SAULNIER MARK GEORGE, WANG ALAN XIANGDONG, GRANT YOUNG KATHARINE A, FRENNESSON DAVID B, SUN LI QIANG, LANGLEY DAVID R, PARCELLA KYLE E
Year of Publication 07.06.2018
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Year of Publication 07.06.2018
Patent
BRIDGED HETEROCYCLES AS HIV INTEGRASE INHIBITORS
WEISS JONATHAN R, MEANWELL NICHOLAS A, LI CHEN, UEDA YASUTSUGU, NAIDU B. NARASIMHULU, OUELLET CARL, CONNOLLY TIMOTHY P, SORENSON MARGARET E, BEAULIEU FRANCIS, WALKER MICHAEL A, PEESE KEVIN M, PATEL MANOJ
Year of Publication 30.12.2010
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Year of Publication 30.12.2010
Patent
The establishment of hepatocyte cell surface polarity during fetal liver development
Feracci, Helene, Connolly, Timothy P., Margolis, Ronald N., Hubbard, Ann L.
Published in Developmental biology (01.09.1987)
Published in Developmental biology (01.09.1987)
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Corrigendum to “Organic reactions in frozen water: Michael addition of amines and thiols to the dehydroalanine side chain of nocathiacins”: [Tetrahedron Lett. 45 (2004) 1059]
Narasimhulu Naidu, B., Lil, Wenying, Sorenson, Margaret E., Connolly, Timothy P., Wichtowski, John A., Zhang, Yunhui, Kim, Oak K., Matiskella, John D., Lam, Kin S., Bronson, Joanne J., Ueda, Yasutsugu
Published in Tetrahedron letters (01.04.2004)
Published in Tetrahedron letters (01.04.2004)
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A short synthesis of 4-substituted 1-(hydroxyalkyl)-1H-pyrazolo[3,4-d]pyrimidines
Zacharie, Boulos, Connolly, Timothy P., Rej, Rabindra, Attardo, Giorgio, Penney, Christopher L.
Published in Tetrahedron (12.02.1996)
Published in Tetrahedron (12.02.1996)
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