Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding
Zhong, Franklin L., Robinson, Kim, Teo, Daniel Eng Thiam, Tan, Kiat-Yi, Lim, Chrissie, Harapas, Cassandra R., Yu, Chien-Hsiung, Xie, William H., Sobota, Radoslaw M., Au, Veonice Bijin, Hopkins, Richard, D'Osualdo, Andrea, Reed, John C., Connolly, John E., Masters, Seth L., Reversade, Bruno
Published in The Journal of biological chemistry (07.12.2018)
Published in The Journal of biological chemistry (07.12.2018)
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High mitochondrial respiration and glycolytic capacity represent a metabolic phenotype of human tolerogenic dendritic cells
Malinarich, Frano, Duan, Kaibo, Hamid, Raudhah Abdull, Bijin, Au, Lin, Wu Xue, Poidinger, Michael, Fairhurst, Anna-Marie, Connolly, John E
Published in The Journal of immunology (1950) (01.06.2015)
Published in The Journal of immunology (1950) (01.06.2015)
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Immunological corollary of the pulmonary mycobiome in bronchiectasis: the CAMEB study
Mac Aogáin, Micheál, Chandrasekaran, Ravishankar, Lim, Albert Yick Hou, Low, Teck Boon, Tan, Gan Liang, Hassan, Tidi, Ong, Thun How, Hui Qi Ng, Amanda, Bertrand, Denis, Koh, Jia Yu, Pang, Sze Lei, Lee, Zi Yang, Gwee, Xiao Wei, Martinus, Christopher, Sio, Yang Yie, Matta, Sri Anusha, Chew, Fook Tim, Keir, Holly R, Connolly, John E, Abisheganaden, John Arputhan, Koh, Mariko Siyue, Nagarajan, Niranjan, Chalmers, James D, Chotirmall, Sanjay H
Published in The European respiratory journal (01.07.2018)
Published in The European respiratory journal (01.07.2018)
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Journal Article
Distinct "Immunoallertypes" of Disease and High Frequencies of Sensitization in Non-Cystic Fibrosis Bronchiectasis
Mac Aogáin, Micheál, Tiew, Pei Yee, Lim, Albert Yick Hou, Low, Teck Boon, Tan, Gan Liang, Hassan, Tidi, Ong, Thun How, Pang, Sze Lei, Lee, Zi Yang, Gwee, Xiao Wei, Martinus, Christopher, Sio, Yang Yie, Matta, Sri Anusha, Ong, Tan Ching, Tiong, Yuen Seng, Wong, Kang Ning, Narayanan, Sriram, Au, Veonice Bijin, Marlier, Damien, Keir, Holly R, Tee, Augustine, Abisheganaden, John Arputhan, Koh, Mariko Siyue, Wang, De Yun, Connolly, John E, Chew, Fook Tim, Chalmers, James D, Chotirmall, Sanjay H
Published in American journal of respiratory and critical care medicine (01.04.2019)
Published in American journal of respiratory and critical care medicine (01.04.2019)
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Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I
Banchereau, Jacques, Connolly, John E, Di Pucchio, Tiziana, Chatterjee, Bithi, Smed-Sörensen, Anna, Clayton, Sandra, Palazzo, Adam, Montes, Monica, Xue, Yaming, Mellman, Ira
Published in Nature immunology (01.05.2008)
Published in Nature immunology (01.05.2008)
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Journal Article
IRF-7 Mediates Type I IFN Responses in Endotoxin-Challenged Mice
Sin, Wei-Xiang, Yeong, Joe Poh-Sheng, Lim, Thomas Jun Feng, Su, I-Hsin, Connolly, John E, Chin, Keh-Chuang
Published in Frontiers in immunology (16.04.2020)
Published in Frontiers in immunology (16.04.2020)
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Leukocyte immunoglobulin-like receptor B1 is critical for antibody-dependent dengue
Chan, Kuan Rong, Ong, Eugenia Z., Tan, Hwee Cheng, Zhang, Summer Li-Xin, Zhang, Qian, Tang, Kin Fai, Kaliaperumal, Nivashini, Pei Chiew Lim, Angeline, Hibberd, Martin L., Chan, Soh Ha, Connolly, John E., Krishnan, Manoj N., Lok, Shee Mei, Hanson, Brendon J., Lin, Chao-Nan, Ooi, Eng Eong
Published in Proceedings of the National Academy of Sciences - PNAS (18.02.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (18.02.2014)
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B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice
Hwang, Sun-Hee, Lee, Huiyin, Yamamoto, Miwako, Jones, Leigh A, Dayalan, Jivanaah, Hopkins, Richard, Zhou, Xin J, Yarovinsky, Felix, Connolly, John E, Curotto de Lafaille, Maria A, Wakeland, Edward K, Fairhurst, Anna-Marie
Published in The Journal of immunology (1950) (15.12.2012)
Published in The Journal of immunology (1950) (15.12.2012)
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TLR7 and TLR9 ligands regulate antigen presentation by macrophages
Celhar, Teja, Pereira-Lopes, Selma, Thornhill, Susannah I, Lee, Hui Yin, Dhillon, Manprit K, Poidinger, Michael, Connolly, John E, Lim, Lina H K, Biswas, Subhra K, Fairhurst, Anna-Marie
Published in International immunology (01.05.2016)
Published in International immunology (01.05.2016)
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A phase I study of an adenoviral vector delivering a MUC1/CD40-ligand fusion protein in patients with advanced adenocarcinoma
Tan, Tira J., Ang, W. X. Gladys, Wang, Who-Whong, Chong, Hui-Shan, Tan, Sze Huey, Cheong, Rachael, Chia, John Whay-Kuang, Syn, Nicholas L., Shuen, Wai Ho, Ba, Rebecca, Kaliaperumal, Nivashini, Au, Bijin, Hopkins, Richard, Li, Xinhua, Tan, Aaron C., Seet, Amanda O. L., Connolly, John E., Arkachaisri, Thaschawee, Chew, Valerie, Lajam, Ahmad bin Mohamed, Guo, Dianyan, Chew, Marvin Z. W., Wasser, Martin, Kumar, Pavanish, Albani, Salvatore, Toh, Han Chong
Published in Nature communications (28.10.2022)
Published in Nature communications (28.10.2022)
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Yaa autoimmune phenotypes are conferred by overexpression of TLR7
Fairhurst, Anna-Marie, Hwang, Sun-hee, Wang, Andrew, Tian, Xiang-Hong, Boudreaux, Christopher, Zhou, Xin J, Casco, Jose, Li, Quan-Zhen, Connolly, John E, Wakeland, Edward K
Published in European journal of immunology (01.07.2008)
Published in European journal of immunology (01.07.2008)
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Journal Article
RNA sensing by conventional dendritic cells is central to the development of lupus nephritis
Celhar, Teja, Hopkins, Richard, Thornhill, Susannah I., De Magalhaes, Raquel, Hwang, Sun-Hee, Lee, Hui-Yin, Yasuga, Hiroko, Jones, Leigh A., Casco, Jose, Lee, Bernett, Thamboo, Thomas P., Zhou, Xin J., Poidinger, Michael, Connolly, John E., Wakeland, Edward K., Fairhurst, Anna-Marie
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2015)
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Journal Article
Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects
He, Qianqian, Au, Bijin, Kulkarni, Madhura, Shen, Yang, Lim, Kah. J., Maimaiti, Jiamila, Wong, Cheng. Kit, Luijten, Monique. N. H., Chong, Han C., Lim, Elaine H., Rancati, Giulia, Sinha, Indrajit, Fu, Zhiyan, Wang, Xiaomeng, Connolly, John. E., Crasta, Karen C.
Published in Oncogenesis (New York, NY) (15.08.2018)
Published in Oncogenesis (New York, NY) (15.08.2018)
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IL‐15‐induced human DC efficiently prime melanoma‐specific naive CD8+ T cells to differentiate into CTL
Dubsky, Peter, Saito, Hiroaki, Leogier, Marylene, Dantin, Carole, Connolly, John E., Banchereau, Jacques, Palucka, A. Karolina
Published in European Journal of Immunology (01.06.2007)
Published in European Journal of Immunology (01.06.2007)
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Multiplex Serum Protein Analysis Identifies Novel Biomarkers of Advanced Fibrosis in Patients with Chronic Liver Disease with the Potential to Improve Diagnostic Accuracy of Established Biomarkers
Irvine, Katharine M, Wockner, Leesa F, Hoffmann, Isabell, Horsfall, Leigh U, Fagan, Kevin J, Bijin, Veonice, Lee, Bernett, Clouston, Andrew D, Lampe, Guy, Connolly, John E, Powell, Elizabeth E
Published in PloS one (18.11.2016)
Published in PloS one (18.11.2016)
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Bayesian analysis of cytokines and chemokine identifies immune pathways of HBsAg loss during chronic hepatitis B treatment
Narayanan, Sriram, Au, Veonice Bijin, Khakpoor, Atefeh, Yan, Cheng, Ahl, Patricia J., Kaliaperumal, Nivashini, Lee, Bernett, Xiang, Wen Wei, Wang, Juling, Lee, Chris, Tay, Amy, Lim, Seng Gee, Connolly, John E.
Published in Scientific reports (02.04.2021)
Published in Scientific reports (02.04.2021)
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Journal Article
Toll‐Like Receptor 9 Deficiency Breaks Tolerance to RNA‐Associated Antigens and Up‐Regulates Toll‐Like Receptor 7 Protein in Sle1 Mice
Celhar, Teja, Yasuga, Hiroko, Lee, Hui Yin, Zharkova, Olga, Tripathi, Shubhita, Thornhill, Susannah I., Lu, Hao K., Au, Bijin, Lim, Lina H. K., Thamboo, Thomas P., Akira, Shizuo, Wakeland, Edward K., Connolly, John E., Fairhurst, Anna‐Marie
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2018)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2018)
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Autophagy Governs Protumorigenic Effects of Mitotic Slippage-induced Senescence
Jakhar, Rekha, Luijten, Monique N H, Wong, Alex X F, Cheng, Bing, Guo, Ke, Neo, Suat P, Au, Bijin, Kulkarni, Madhura, Lim, Kah J, Maimaiti, Jiamila, Chong, Han C, Lim, Elaine H, Tan, Tee B K, Ong, Kong W, Sim, Yirong, Wong, Jill S L, Khoo, James B K, Ho, Juliana T S, Chua, Boon T, Sinha, Indrajit, Wang, Xiaomeng, Connolly, John E, Gunaratne, Jayantha, Crasta, Karen C
Published in Molecular cancer research (01.11.2018)
Published in Molecular cancer research (01.11.2018)
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Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients
Sung, Cynthia, Wei, Yuan, Watanabe, Satoru, Lee, How Sung, Khoo, Yok Moi, Fan, Lu, Rathore, Abhay P S, Chan, Kitti Wing-Ki, Choy, Milly M, Kamaraj, Uma S, Sessions, October M, Aw, Pauline, de Sessions, Paola F, Lee, Bernett, Connolly, John E, Hibberd, Martin L, Vijaykrishna, Dhanasekaran, Wijaya, Limin, Ooi, Eng Eong, Low, Jenny Guek-Hong, Vasudevan, Subhash G
Published in PLoS neglected tropical diseases (10.08.2016)
Published in PLoS neglected tropical diseases (10.08.2016)
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