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Placebo-Controlled Trial of Tofacitinib Monotherapy in Rheumatoid Arthritis
Fleischmann, Roy, Kremer, Joel, Cush, John, Schulze-Koops, Hendrik, Connell, Carol A, Bradley, John D, Gruben, David, Wallenstein, Gene V, Zwillich, Samuel H, Kanik, Keith S
Published in The New England journal of medicine (09.08.2012)
Published in The New England journal of medicine (09.08.2012)
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Postapproval Comparative Safety Study of Tofacitinib and Biological Disease‐Modifying Antirheumatic Drugs: 5‐Year Results from a United States–Based Rheumatoid Arthritis Registry
Kremer, Joel M., Bingham, Clifton O., Cappelli, Laura C., Greenberg, Jeffrey D., Madsen, Ann M., Geier, Jamie, Rivas, Jose L., Onofrei, Alina M., Barr, Christine J., Pappas, Dimitrios A., Litman, Heather J., Dandreo, Kimberly J., Shapiro, Andrea B., Connell, Carol A., Kavanaugh, Arthur
Published in ACR open rheumatology (01.03.2021)
Published in ACR open rheumatology (01.03.2021)
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Treatment outcomes in patients with seropositive versus seronegative rheumatoid arthritis in Phase III randomised clinical trials of tofacitinib
Bird, Paul, Hall, Stephen, Nash, Peter, Connell, Carol A, Kwok, Kenneth, Witcombe, David, Thirunavukkarasu, Krishan
Published in Rheumatic & musculoskeletal diseases open (01.02.2019)
Published in Rheumatic & musculoskeletal diseases open (01.02.2019)
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Is radiographic progression in modern rheumatoid arthritis trials still a robust outcome? Experience from tofacitinib clinical trials
Landewé, Robert B. M., Connell, Carol A., Bradley, John D., Wilkinson, Bethanie, Gruben, David, Strengholt, Sander, van der Heijde, Désirée
Published in Arthritis research & therapy (23.09.2016)
Published in Arthritis research & therapy (23.09.2016)
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Fracture in clinical studies of tofacitinib in rheumatoid arthritis
Hansen, Karen E., Mortezavi, Mahta, Nagy, Edward, Wang, Cunshan, Connell, Carol A., Radi, Zaher, Litman, Heather J., Adami, Giovanni, Rossini, Maurizio
Published in Therapeutic advances in musculoskeletal disease (01.01.2022)
Published in Therapeutic advances in musculoskeletal disease (01.01.2022)
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Risk of extended major adverse cardiovascular event endpoints with tofacitinib versus TNF inhibitors in patients with rheumatoid arthritis: a post hoc analysis of a phase 3b/4 randomised safety study
Buch, Maya H, Bhatt, Deepak L, Charles-Schoeman, Christina, Giles, Jon T, Mikuls, Ted, Koch, Gary G, Ytterberg, Steven, Nagy, Edward, Jo, Hyejin, Kwok, Kenneth, Connell, Carol A, Masri, Karim Richard, Yndestad, Arne
Published in Rheumatic & musculoskeletal diseases open (12.04.2024)
Published in Rheumatic & musculoskeletal diseases open (12.04.2024)
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Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis
Ytterberg, Steven R, Bhatt, Deepak L, Mikuls, Ted R, Koch, Gary G, Fleischmann, Roy, Rivas, Jose L, Germino, Rebecca, Menon, Sujatha, Sun, Yanhui, Wang, Cunshan, Shapiro, Andrea B, Kanik, Keith S, Connell, Carol A
Published in The New England journal of medicine (27.01.2022)
Published in The New England journal of medicine (27.01.2022)
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Risk of major adverse cardiovascular events with tofacitinib versus tumour necrosis factor inhibitors in patients with rheumatoid arthritis with or without a history of atherosclerotic cardiovascular disease: a post hoc analysis from ORAL Surveillance
Charles-Schoeman, Christina, Buch, Maya H, Dougados, Maxime, Bhatt, Deepak L, Giles, Jon T, Ytterberg, Steven R, Koch, Gary G, Vranic, Ivana, Wu, Joseph, Wang, Cunshan, Kwok, Kenneth, Menon, Sujatha, Rivas, Jose L, Yndestad, Arne, Connell, Carol A, Szekanecz, Zoltan
Published in Annals of the rheumatic diseases (01.01.2023)
Published in Annals of the rheumatic diseases (01.01.2023)
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Malignancy risk with tofacitinib versus TNF inhibitors in rheumatoid arthritis: results from the open-label, randomised controlled ORAL Surveillance trial
Curtis, Jeffrey R, Yamaoka, Kunihiro, Chen, Yi-Hsing, Bhatt, Deepak L, Gunay, Levent M, Sugiyama, Naonobu, Connell, Carol A, Wang, Cunshan, Wu, Joseph, Menon, Sujatha, Vranic, Ivana, Gómez-Reino, Juan J
Published in Annals of the rheumatic diseases (01.03.2023)
Published in Annals of the rheumatic diseases (01.03.2023)
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Tofacitinib (CP‐690,550) in patients with rheumatoid arthritis receiving methotrexate: Twelve‐month data from a twenty‐four–month phase III randomized radiographic study
van der Heijde, Désirée, Tanaka, Yoshiya, Fleischmann, Roy, Keystone, Edward, Kremer, Joel, Zerbini, Cristiano, Cardiel, Mario H., Cohen, Stanley, Nash, Peter, Song, Yeong‐Wook, Tegzová, Dana, Wyman, Bradley T., Gruben, David, Benda, Birgitta, Wallenstein, Gene, Krishnaswami, Sriram, Zwillich, Samuel H., Bradley, John D., Connell, Carol A.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2013)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2013)
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Infections in patients with rheumatoid arthritis receiving tofacitinib versus tumour necrosis factor inhibitors: results from the open-label, randomised controlled ORAL Surveillance trial
Balanescu, Andra-Rodica, Citera, Gustavo, Pascual-Ramos, Virginia, Bhatt, Deepak L, Connell, Carol A, Gold, David, Chen, All-Shine, Sawyerr, Gosford, Shapiro, Andrea B, Pope, Janet E, Schulze-Koops, Hendrik
Published in Annals of the rheumatic diseases (01.11.2022)
Published in Annals of the rheumatic diseases (01.11.2022)
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Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis. Reply
Ytterberg, Steven R, Bhatt, Deepak L, Connell, Carol A
Published in The New England journal of medicine (05.05.2022)
Published in The New England journal of medicine (05.05.2022)
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Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs
Fleischmann, Roy, Cutolo, Maurizio, Genovese, Mark C., Lee, Eun Bong, Kanik, Keith S., Sadis, Seth, Connell, Carol A., Gruben, David, Krishnaswami, Sriram, Wallenstein, Gene, Wilkinson, Bethanie E., Zwillich, Samuel H.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2012)
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A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone
Kremer, Joel M., Cohen, Stanley, Wilkinson, Bethanie E., Connell, Carol A., French, Jonathan L., Gomez-Reino, Juan, Gruben, David, Kanik, Keith S., Krishnaswami, Sriram, Pascual-Ramos, Virginia, Wallenstein, Gene, Zwillich, Samuel H.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2012)
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Age-based (<65 vs ≥65 years) incidence of infections and serious infections with tofacitinib versus biological DMARDs in rheumatoid arthritis clinical trials and the US Corrona RA registry
Winthrop, Kevin L, Citera, Gustavo, Gold, David, Henrohn, Dan, Connell, Carol A, Shapiro, Andrea B, Shi, Harry, Onofrei, Alina M, Pappas, Dimitrios A, Schulze-Koops, Hendrik
Published in Annals of the rheumatic diseases (01.01.2021)
Published in Annals of the rheumatic diseases (01.01.2021)
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Risk of Venous Thromboembolism With Tofacitinib Versus Tumor Necrosis Factor Inhibitors in Cardiovascular Risk‐Enriched Rheumatoid Arthritis Patients
Charles‐Schoeman, Christina, Fleischmann, Roy, Mysler, Eduardo, Greenwald, Maria, Ytterberg, Steven R., Koch, Gary G., Bhatt, Deepak L., Wang, Cunshan, Mikuls, Ted R., Chen, All‐shine, Connell, Carol A., Woolcott, John C., Menon, Sujatha, Chen, Yan, Lee, Kristen, Szekanecz, Zoltán
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2024)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2024)
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Impact of cardiovascular risk enrichment on incidence of major adverse cardiovascular events in the tofacitinib rheumatoid arthritis clinical programme
Dougados, Maxime, Charles-Schoeman, Christina, Szekanecz, Zoltán, Giles, Jon T, Ytterberg, Steven R, Bhatt, Deepak L, Koch, Gary G, Vranic, Ivana, Wu, Joseph, Wang, Cunshan, Kwok, Kenneth, Menon, Sujatha, Connell, Carol A, Yndestad, Arne, Rivas, Jose L, Buch, Maya H
Published in Annals of the rheumatic diseases (01.04.2023)
Published in Annals of the rheumatic diseases (01.04.2023)
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Open-label tofacitinib and double-blind atorvastatin in rheumatoid arthritis patients: a randomised study
McInnes, Iain B, Kim, Ho-Youn, Lee, Sang-Heon, Mandel, David, Song, Yeong-Wook, Connell, Carol A, Luo, Zhen, Brosnan, M Julia, Zuckerman, Andrea, Zwillich, Samuel H, Bradley, John D
Published in Annals of the rheumatic diseases (01.01.2014)
Published in Annals of the rheumatic diseases (01.01.2014)
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A pooled analysis of the safety of tofacitinib as monotherapy or in combination with background conventional synthetic disease-modifying antirheumatic drugs in a Phase 3 rheumatoid arthritis population
Kivitz, Alan J., Cohen, Stanley, Keystone, Edward, van Vollenhoven, Ronald F., Haraoui, Boulos, Kaine, Jeffrey, Fan, Haiyun, Connell, Carol A., Bananis, Eustratios, Takiya, Liza, Fleischmann, Roy
Published in Seminars in arthritis and rheumatism (01.12.2018)
Published in Seminars in arthritis and rheumatism (01.12.2018)
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Assessment of the Effects of Inhibition or Induction of CYP2C19 and CYP2C9 Enzymes, or Inhibition of OAT3, on the Pharmacokinetics of Abrocitinib and Its Metabolites in Healthy Individuals
Wang, Xiaoxing, Dowty, Martin E., Wouters, Ann, Tatulych, Svitlana, Connell, Carol A., Le, Vu H., Tripathy, Sakambari, O’Gorman, Melissa T., Winton, Jennifer A., Yin, Natalie, Valdez, Hernan, Malhotra, Bimal K.
Published in European journal of drug metabolism and pharmacokinetics (01.05.2022)
Published in European journal of drug metabolism and pharmacokinetics (01.05.2022)
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