Differential Requirements for eIF4E Dose in Normal Development and Cancer
Truitt, Morgan L., Conn, Crystal S., Shi, Zhen, Pang, Xiaming, Tokuyasu, Taku, Coady, Alison M., Seo, Youngho, Barna, Maria, Ruggero, Davide
Published in Cell (02.07.2015)
Published in Cell (02.07.2015)
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Journal Article
Development of a stress response therapy targeting aggressive prostate cancer
Nguyen, Hao G, Conn, Crystal S, Kye, Yae, Xue, Lingru, Forester, Craig M, Cowan, Janet E, Hsieh, Andrew C, Cunningham, John T, Truillet, Charles, Tameire, Feven, Evans, Michael J, Evans, Christopher P, Yang, Joy C, Hann, Byron, Koumenis, Constantinos, Walter, Peter, Carroll, Peter R, Ruggero, Davide
Published in Science translational medicine (02.05.2018)
Published in Science translational medicine (02.05.2018)
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Journal Article
The integrated stress response in cancer progression: a force for plasticity and resistance
Lines, Caleb L., McGrath, Morgan J., Dorwart, Tanis, Conn, Crystal S.
Published in Frontiers in oncology (03.08.2023)
Published in Frontiers in oncology (03.08.2023)
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Journal Article
Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVID-19
Ha, Dat P, Shin, Woo-Jin, Liu, Ze, Doche, Michael E, Lau, Roy, Leli, Nektaria Maria, Conn, Crystal S, Russo, Mariangela, Lorenzato, Annalisa, Koumenis, Constantinos, Yu, Min, Mumenthaler, Shannon M, Lee, Amy S
Published in Cell & bioscience (06.09.2024)
Published in Cell & bioscience (06.09.2024)
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Journal Article
Reduced eIF4E function impairs B-cell leukemia without altering normal B-lymphocyte function
Chiu, Honyin, Buono, Roberta, Jackson, Leandra V., Herzog, Lee-or, Mallya, Sharmila, Conn, Crystal S., Ruggero, Davide, Fruman, David A.
Published in iScience (23.07.2021)
Published in iScience (23.07.2021)
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Journal Article
ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression
Tameire, Feven, Verginadis, Ioannis I., Leli, Nektaria Maria, Polte, Christine, Conn, Crystal S., Ojha, Rani, Salas Salinas, Carlo, Chinga, Frank, Monroy, Alexandra. M., Fu, Weixuan, Wang, Paul, Kossenkov, Andrew, Ye, Jiangbin, Amaravadi, Ravi K., Ignatova, Zoya, Fuchs, Serge Y., Diehl, J. Alan, Ruggero, Davide, Koumenis, Constantinos
Published in Nature cell biology (01.07.2019)
Published in Nature cell biology (01.07.2019)
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Journal Article
PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
Zhang, Duo, Li, Albert M., Hu, Guanghui, Huang, Menggui, Yang, Fan, Zhang, Lin, Wellen, Kathryn E., Xu, Xiaowei, Conn, Crystal S., Zou, Wei, Kahn, Mark, Rhoades, Seth D., Weljie, Aalim M., Fuchs, Serge Y., Amankulor, Nduka, Yoshor, Daniel, Ye, Jiangbin, Koumenis, Constantinos, Gong, Yanqing, Fan, Yi
Published in Cell metabolism (07.03.2023)
Published in Cell metabolism (07.03.2023)
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Journal Article
Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance
Wei, Jiajie, Kishton, Rigel J., Angel, Matthew, Conn, Crystal S., Dalla-Venezia, Nicole, Marcel, Virginie, Vincent, Anne, Catez, Frédéric, Ferré, Sabrina, Ayadi, Lilia, Marchand, Virginie, Dersh, Devin, Gibbs, James S., Ivanov, Ivaylo P., Fridlyand, Nathan, Couté, Yohann, Diaz, Jean-Jacques, Qian, Shu-Bing, Staudt, Louis M., Restifo, Nicholas P., Yewdell, Jonathan W.
Published in Molecular cell (21.03.2019)
Published in Molecular cell (21.03.2019)
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Journal Article
Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
Gwinn, Dana M., Lee, Alex G., Briones-Martin-del-Campo, Marcela, Conn, Crystal S., Simpson, David R., Scott, Anna I., Le, Anthony, Cowan, Tina M., Ruggero, Davide, Sweet-Cordero, E. Alejandro
Published in Cancer cell (08.01.2018)
Published in Cancer cell (08.01.2018)
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Journal Article
PI3K-mTORC1 Attenuates Stress Response by Inhibiting Cap-independent Hsp70 Translation
Sun, Jun, Conn, Crystal S., Han, Yan, Yeung, Vincent, Qian, Shu-Bing
Published in The Journal of biological chemistry (25.02.2011)
Published in The Journal of biological chemistry (25.02.2011)
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Journal Article
The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity
Conn, Crystal S, Yang, Haojun, Tom, Harrison J, Ikeda, Kenji, Oses-Prieto, Juan A, Vu, Hieu, Oguri, Yasuo, Nair, Supna, Gill, Ryan M, Kajimura, Shingo, DeBerardinis, Ralph J, Burlingame, Alma L, Ruggero, Davide
Published in Nature metabolism (01.02.2021)
Published in Nature metabolism (01.02.2021)
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Journal Article
Author Correction: ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression
Tameire, Feven, Verginadis, Ioannis I., Leli, Nektaria Maria, Polte, Christine, Conn, Crystal S., Ojha, Rani, Salinas, Carlo Salas, Chinga, Frank, Monroy, Alexandra. M., Fu, Weixuan, Wang, Paul, Kossenkov, Andrew, Ye, Jiangbin, Amaravadi, Ravi K., Ignatova, Zoya, Fuchs, Serge Y., Diehl, J. Alan, Ruggero, Davide, Koumenis, Constantinos
Published in Nature cell biology (01.08.2019)
Published in Nature cell biology (01.08.2019)
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Journal Article
Noninvasive Measurement of mTORC1 Signaling with 89Zr-Transferrin
Truillet, Charles, Cunningham, John T., Parker, Matthew F.L., Huynh, Loc T., Conn, Crystal S., Ruggero, Davide, Lewis, Jason S., Evans, Michael J.
Published in Clinical cancer research (15.06.2017)
Published in Clinical cancer research (15.06.2017)
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Journal Article
Noninvasive Measurement of mTORC1 Signaling with 89 Zr-Transferrin
Truillet, Charles, Cunningham, John T, Parker, Matthew F L, Huynh, Loc T, Conn, Crystal S, Ruggero, Davide, Lewis, Jason S, Evans, Michael J
Published in Clinical cancer research (15.06.2017)
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Published in Clinical cancer research (15.06.2017)
Journal Article
Abstract A25: Sensing stress in cancer: a novel therapy targeting protein synthesis through the unfolded protein response in prostate cancer development
Conn, Crystal S., Nguyen, Hao G., Kye, Yae, Cunningham, John T., Truillet, Charles, Evans, Michael, Huynh, Tony L., Walters, Peter, Ruggero, Davide
Published in Cancer research (Chicago, Ill.) (15.03.2017)
Published in Cancer research (Chicago, Ill.) (15.03.2017)
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