Preclinical evaluation of Insulin-like growth factor receptor 1 (IGF1R) and Insulin Receptor (IR) as a therapeutic targets in triple negative breast cancer
Roche, Sandra, Gaule, Patricia, Winrow, Deirdre, Mukherjee, Nupur, O'Neill, Fiona, Conlon, Neil T, Meiller, Justine, Collins, Denis M, Canonici, Alexandra, Fawsi, Mohammed Ibrahim, Estepa-Fernández, Alejandra, Madden, Stephen F, Crown, John, O'Donovan, Norma, Eustace, Alex J
Published in PloS one (15.03.2023)
Published in PloS one (15.03.2023)
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Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2 -Mutated Breast Cancer
Collins, Denis M, Conlon, Neil T, Kannan, Srinivasaraghavan, Verma, Chandra S, Eli, Lisa D, Lalani, Alshad S, Crown, John
Published in Cancers (28.05.2019)
Published in Cancers (28.05.2019)
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Correction: PP2A inhibition overcomes acquired resistance to HER2 targeted therapy
McDermott, Martina S. J., Browne, Brigid C., Conlon, Neil T., O’Brien, Neil A., Slamon, Dennis J., Henry, Michael, Meleady, Paula, Clynes, Martin, Dowling, Paul, Crown, John, O’Donovan, Norma
Published in Molecular cancer (30.10.2023)
Published in Molecular cancer (30.10.2023)
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Could MicroRNAs Be Useful Tools to Improve the Diagnosis and Treatment of Rare Gynecological Cancers? A Brief Overview
Di Fiore, Riccardo, Suleiman, Sherif, Pentimalli, Francesca, O'Toole, Sharon A, O'Leary, John J, Ward, Mark P, Conlon, Neil T, Sabol, Maja, Ozretić, Petar, Erson-Bensan, Ayse Elif, Reed, Nicholas, Giordano, Antonio, Herrington, C Simon, Calleja-Agius, Jean
Published in International journal of molecular sciences (07.04.2021)
Published in International journal of molecular sciences (07.04.2021)
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Establishment and Characterisation by Expression Microarray of Patient-Derived Xenograft Panel of Human Pancreatic Adenocarcinoma Patients
Roche, Sandra, O'Neill, Fiona, Murphy, Jean, Swan, Niall, Meiller, Justine, Conlon, Neil T, Geoghegan, Justin, Conlon, Kevin, McDermott, Ray, Rahman, Rozana, Toomey, Sinead, Straubinger, Ninfa L, Straubinger, Robert M, O'Connor, Robert, McVey, Gerard, Moriarty, Michael, Clynes, Martin
Published in International journal of molecular sciences (31.01.2020)
Published in International journal of molecular sciences (31.01.2020)
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Alteration in Levels of Specific miRNAs and Their Potential Protein Targets between Human Pancreatic Cancer Samples, Adjacent Normal Tissue, and Xenografts Derived from These Tumors
O'Neill, Fiona, Allen-Coyle, Taylor-Jade, Roche, Sandra, Meiller, Justine, Conlon, Neil T, Swan, Niall, Straubinger, Robert M, Geoghegan, Justin, Straubinger, Ninfa L, Conlon, Kevin, McDermott, Ray, O'Sullivan, Finbarr, Henry, Michael, Meleady, Paula, McVey, Gerard, O'Connor, Robert, Moriarty, Michael, Clynes, Martin
Published in Life (Basel, Switzerland) (22.02.2023)
Published in Life (Basel, Switzerland) (22.02.2023)
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Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL
Eustace, Alex J, Conlon, Neil T, McDermott, Martina S J, Browne, Brigid C, O'Leary, Patrick, Holmes, Frankie A, Espina, Virginia, Liotta, Lance A, O'Shaughnessy, Joyce, Gallagher, Clair, O'Driscoll, Lorraine, Rani, Sweta, Madden, Stephen F, O'Brien, Neil A, Ginther, Charles, Slamon, Dennis, Walsh, Naomi, Gallagher, William M, Zagozdzon, Radoslaw, Watson, William R, O'Donovan, Norma, Crown, John
Published in BMC cancer (11.10.2018)
Published in BMC cancer (11.10.2018)
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GYNOCARE Update: Modern Strategies to Improve Diagnosis and Treatment of Rare Gynecologic Tumors—Current Challenges and Future Directions
Di Fiore, Riccardo, Suleiman, Sherif, Ellul, Bridget, O'Toole, Sharon A, Savona-Ventura, Charles, Felix, Ana, Napolioni, Valerio, Conlon, Neil T, Kahramanoglu, Ilker, Azzopardi, Miriam J, Dalmas, Miriam, Calleja, Neville, Brincat, Mark R, Muscat-Baron, Yves, Sabol, Maja, Dimitrievska, Vera, Yordanov, Angel, Vasileva-Slaveva, Mariela, von Brockdorff, Kristelle, Micallef, Rachel A, Kubelac, Paul, Achimaș-Cadariu, Patriciu, Vlad, Catalin, Tzortzatou, Olga, Poka, Robert, Giordano, Antonio, Felice, Alex, Reed, Nicholas, Herrington, C Simon, Faraggi, David, Calleja-Agius, Jean
Published in Cancers (27.01.2021)
Published in Cancers (27.01.2021)
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Journal Article
Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer
Canonici, Alexandra, Browne, Alacoque L., Ibrahim, Mohamed F. K., Fanning, Kevin P., Roche, Sandra, Conlon, Neil T., O’Neill, Fiona, Meiller, Justine, Cremona, Mattia, Morgan, Clare, Hennessy, Bryan T., Eustace, Alex J., Solca, Flavio, O’Donovan, Norma, Crown, John
Published in Therapeutic advances in medical oncology (01.01.2020)
Published in Therapeutic advances in medical oncology (01.01.2020)
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Journal Article
PP2A inhibition overcomes acquired resistance to HER2 targeted therapy
McDermott, Martina Sj, Browne, Brigid C, Conlon, Neil T, O'Brien, Neil A, Slamon, Dennis J, Henry, Michael, Meleady, Paula, Clynes, Martin, Dowling, Paul, Crown, John, O'Donovan, Norma
Published in Molecular cancer (24.06.2014)
Published in Molecular cancer (24.06.2014)
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A Comparative Quantitative LC-MS/MS Profiling Analysis of Human Pancreatic Adenocarcinoma, Adjacent-Normal Tissue, and Patient-Derived Tumour Xenografts
Coleman, Orla, Henry, Michael, O'Neill, Fiona, Roche, Sandra, Swan, Niall, Boyle, Lorraine, Murphy, Jean, Meiller, Justine, Conlon, Neil T, Geoghegan, Justin, Conlon, Kevin C, Lynch, Vincent, Straubinger, Ninfa L, Straubinger, Robert M, McVey, Gerard, Moriarty, Michael, Meleady, Paula, Clynes, Martin
Published in Proteomes (06.11.2018)
Published in Proteomes (06.11.2018)
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Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors
Conlon, Neil T, Kooijman, Jeffrey J, van Gerwen, Suzanne J C, Mulder, Winfried R, Zaman, Guido J R, Diala, Irmina, Eli, Lisa D, Lalani, Alshad S, Crown, John, Collins, Denis M
Published in British journal of cancer (30.03.2021)
Published in British journal of cancer (30.03.2021)
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Journal Article
FOLFIRINOX Pharmacodynamic Interactions in 2D and 3D Pancreatic Cancer Cell Cultures
Allen-Coyle, Taylor J., Niu, Jin, Welsch, Eva, Conlon, Neil T., Garner, Weylon, Clynes, Martin, O’Sullivan, Finbarr, Straubinger, Robert M., Mager, Donald E., Roche, Sandra
Published in The AAPS journal (13.10.2022)
Published in The AAPS journal (13.10.2022)
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Journal Article
HER-targeted tyrosine kinase inhibitors enhance response to trastuzumab and pertuzumab in HER2-positive breast cancer
Canonici, Alexandra, Ivers, Laura, Conlon, Neil T., Pedersen, Kasper, Gaynor, Nicola, Browne, Brigid C., O’Brien, Neil A., Gullo, Giuseppe, Collins, Denis M., O’Donovan, Norma, Crown, John
Published in Investigational new drugs (01.06.2019)
Published in Investigational new drugs (01.06.2019)
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Journal Article
Neratinib plus dasatinib is highly synergistic in HER2-positive breast cancer in vitro and in vivo
Conlon, Neil T, Roche, Sandra, Mahdi, Amira F, Browne, Alacoque, Breen, Laura, Gaubatz, Johanna, Meiller, Justine, O'Neill, Fiona, O'Driscoll, Lorraine, Cremona, Mattia, Hennessy, Bryan T, Eli, Lisa D, Crown, John, Collins, Denis M
Published in Translational oncology (01.11.2024)
Published in Translational oncology (01.11.2024)
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Journal Article
The HSP90 inhibitor NVP-AUY922 inhibits growth of HER2 positive and trastuzumab-resistant breast cancer cells
Canonici, Alexandra, Qadir, Zulfiqar, Conlon, Neil T., Collins, Denis M., O’Brien, Neil A., Walsh, Naomi, Eustace, Alex J., O’Donovan, Norma, Crown, John
Published in Investigational new drugs (01.08.2018)
Published in Investigational new drugs (01.08.2018)
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Journal Article
Abstract 1773: Targeting HER2 and Src in HER2-driven ovarian and esophagogastric cancers
Conlon, Neil T., Kroh, Keshia, Crown, John, Collins, Denis M.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract P2-13-36: Comparative time course analysis of the effects of neratinib, lapatinib and tucatinib in an in vitro HER2+ breast cancer model
Castel, Myra E, Conlon, Neil T, Walsh, Naomi, Diala, Irmina, Eli, Lisa, Crown, John, Collins, Denis M
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Journal Article
Abstract B034: Targeting the HER family/Src pathways in ovarian cancer
Conlon, Neil T., Mörhle, Elena, Collins, Denis M., Crown, John
Published in Cancer research (Chicago, Ill.) (04.03.2024)
Published in Cancer research (Chicago, Ill.) (04.03.2024)
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