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A randomized, double‐blind, single‐dose, three‐arm, parallel group study to determine pharmacokinetic similarity of ABP 959 and eculizumab (Soliris®) in healthy male subjects
Chow, Vincent, Pan, Jean, Chien, David, Mytych, Daniel T., Hanes, Vladimir
Published in European journal of haematology (01.07.2020)
Published in European journal of haematology (01.07.2020)
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Complement activation in polycystic ovary syndrome occurs in the postprandial and fasted state and is influenced by obesity and insulin sensitivity
Lewis, Ruth D., Narayanaswamy, Anil K., Farewell, Daniel, Rees, Dafydd Aled
Published in Clinical endocrinology (Oxford) (01.01.2021)
Published in Clinical endocrinology (Oxford) (01.01.2021)
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Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity
Gregersen, Emil, Betzer, Cristine, Kim, Woojin S., Kovacs, Gergo, Reimer, Lasse, Halliday, Glenda M., Thiel, Steffen, Jensen, Poul Henning
Published in Journal of neuroinflammation (16.08.2021)
Published in Journal of neuroinflammation (16.08.2021)
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Results of a phase 1/2 study of cemdisiran in healthy subjects and patients with paroxysmal nocturnal hemoglobinuria
Gaya, Anna, Munir, Talha, Urbano‐Ispizua, Alvaro, Griffin, Morag, Taubel, Jorg, Bush, Jim, Bhan, Ishir, Borodovsky, Anna, Wang, Yue, Badri, Prajakta, Garg, Pushkal
Published in EJHaem (01.08.2023)
Published in EJHaem (01.08.2023)
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Complement component C5 iRNA compositions and methods of use thereof
MANOHARAN, Muthiah, BETTENCOURT, Brian, FOSTER, Donald, BUTLER, James, MAIER, Martin, BORODOVSKY, Anna, CHARISSE, Klaus, FITZGERALD, Kevin, KUCHIMANCHI, Satyanarayana, RAJEEV, Kallanthottathil G
Year of Publication 24.07.2025
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Year of Publication 24.07.2025
Patent
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iTRAQ‐Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism
Shen, Liming, Zhang, Kaoyuan, Feng, Chengyun, Chen, Youjiao, Li, Shuiming, Iqbal, Javed, Liao, Liping, Zhao, Yuxi, Zhai, Jian
Published in Proteomics. Clinical applications (01.05.2018)
Published in Proteomics. Clinical applications (01.05.2018)
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COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Manoharan, Muthiah, Kuchimanchi, Satyanarayana, Maier, Martin A, Bettencourt, Brian, Charisse, Klaus, Rajeev, Kallanthottathil G, Borodovsky, Anna, Butler, James, Fitzgerald, Kevin, Foster, Donald
Year of Publication 15.08.2024
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Year of Publication 15.08.2024
Patent
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Cerebrospinal Fluid Profiles in Parkinson’s Disease: No Accumulation of Glucosylceramide, but Significant Downregulation of Active Complement C5 Fragment
Niimi, Yoshiki, Mizutani, Yasuaki, Akiyama, Hisako, Watanabe, Hirohisa, Shiroki, Ryoichi, Hirabayashi, Yoshio, Hoshinaga, Kiyotaka, Mutoh, Tatsuro
Published in Journal of Parkinson's disease (01.01.2021)
Published in Journal of Parkinson's disease (01.01.2021)
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Complement component C5 iRNA compositions and methods of use thereof
Manoharan, Muthiah, Kuchimanchi, Satyanarayana, Maier, Martin A, Bettencourt, Brian, Charisse, Klaus, Rajeev, Kallanthottathil G, Borodovsky, Anna, Butler, James, Fitzgerald, Kevin, Foster, Donald
Year of Publication 16.01.2024
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Year of Publication 16.01.2024
Patent
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COMPLEMENT COMPONENT C5 IRNA COMPOSITIONS AND METHODS OF USE THEREOF
BORODOVSKY, ANNA, BUTLER, JAMES, KUCHIMANCHI, SATYANARAYANA, CHARISSE, KLAUS, RAJEEV, KALLANTHOTTATHIL G, BETTENCOURT, BRIAN, FITZGERALD, KEVIN, MANOHARAN, MUTHIAH, FOSTER, DONALD, MAIER, MARTIN
Year of Publication 05.12.2023
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Year of Publication 05.12.2023
Patent
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Complement component C5 iRNA compositions and methods of use thereof
MANOHARAN, Muthiah, BETTENCOURT, Brian, FOSTER, Donald, BUTLER, James, MAIER, Martin, BORODOVSKY, Anna, CHARISSE, Klaus, FITZGERALD, Kevin, KUCHIMANCHI, Satyanarayana, RAJEEV, Kallanthottathil G
Year of Publication 13.04.2023
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Year of Publication 13.04.2023
Patent
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