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Association of single nucleotide polymorphism in complement factor I gene with age-related macular degeneration
Wu, Pei-bei, Gu, Hong, Yang, Xiu-fen, Liu, Ning-pu
Published in Chung-hua yen k'o tsa chih (01.04.2013)
Published in Chung-hua yen k'o tsa chih (01.04.2013)
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Inflammatory cytokines, complement factor H and anhedonia in drug-naïve major depressive disorder
Tang, Wei, Liu, Hongyang, Chen, Lixian, Zhao, Ke, Zhang, Yaoyao, Zheng, Ke, Zhu, Cheng, Zheng, Tiansheng, Liu, Jiahong, Wang, Dandan, Yu, Lingfang, Fang, Xinyu, Zhang, Chen, Su, Kuan-Pin
Published in Brain, behavior, and immunity (01.07.2021)
Published in Brain, behavior, and immunity (01.07.2021)
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Variants in Complement Factor H and Complement Factor H-Related Protein Genes, CFHR3 and CFHR1, Affect Complement Activation in IgA Nephropathy
Zhu, Li, Zhai, Ya-Ling, Wang, Feng-Mei, Hou, Ping, Lv, Ji-Cheng, Xu, Da-Min, Shi, Su-Fang, Liu, Li-Jun, Yu, Feng, Zhao, Ming-Hui, Novak, Jan, Gharavi, Ali G., Zhang, Hong
Published in Journal of the American Society of Nephrology (01.05.2015)
Published in Journal of the American Society of Nephrology (01.05.2015)
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A monoclonal antibody targeting amyloid β (Aβ) restores complement factor I bioactivity: Potential implications in age-related macular degeneration and Alzheimer’s disease
Lashkari, Kameran, Teague, Gianna, Chen, Hong, Lin, Yong-Qing, Kumar, Sanjay, McLaughlin, Megan M., López, Francisco J.
Published in PloS one (21.05.2018)
Published in PloS one (21.05.2018)
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Multiple‐ascending doses of ACT‐1014‐6470, an oral complement factor 5a receptor 1 (C5a1 receptor) antagonist: Tolerability, pharmacokinetics and target engagement
Anliker‐Ort, Marion, Dingemanse, Jasper, Farine, Hervé, Groenen, Peter, Kornberger, Rüdiger, Anker, John, Kaufmann, Priska
Published in British journal of clinical pharmacology (01.01.2023)
Published in British journal of clinical pharmacology (01.01.2023)
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Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn’s disease and leads to impaired CFB cleavage and phagocytosis
Stamps, Dalton T, Dube, Shishir, Li, Dalin, Yang, Shaohong, Landers, Carol J, Mengesha, Emebet, Murali, Ramachandran, Potdar, Alka A, Wolf, Andrea J, Botwin, Gregory J, Khrom, Michelle, Faubion, William A, Sandler, Robert S, Sartor, R Balfour, Brant, Steven R, Rioux, John D, Schumm, L Philip, Silverberg, Mark S, Zaghiyan, Karen, Melmed, Gil Y, Vasiliauskas, Eric A, Syal, Gaurav, Bonthala, Nirupama N, Targan, Stephan R, Michelsen, Kathrin S, Ahmad, Tariq, Amininejad, Leila, Andersen, Vibeke, Aumais, Guy, Baidoo, Leonard, Bayless, Theodore M, Bethge, Johannes, Boucher, Gabrielle, Brand, Stephan, Chew, Angela, Cho, Judy H, Cohain, Ariella, Jong, Dirk De, Denson, Lee A, Dewit, Olivier, D'Inca, Renata, Edwards, Cathryn, Ellinghaus, David, Festen, Eleonora A, Florin, Tim, Gieger, Christian, Goyette, Philippe, Green, Todd, Griffiths, Anne M, Hakonarson, Hakon, Hanigan, Katherine, Hart, Ailsa, Hayward, Nicholas K, Hugot, Jean-Pierre, Hui, Ken Y, Imielinski, Marcin, Jonaitis, Laimas, Jostins, Luke, Kiudelis, Gediminas, Krishnaprasad, Krupa, Kugathasan, Subra, Lee, James C, Lees, Charlie W, Leja, Marcis, Louis, Edouard, Mitrovic, Mitja, Ng, Aylwin, Ng, Siew C, Evelyn Ng, Sok Meng, Nikolaus, Susanna, Oikonomou, Ioannis, Phillips, Anne, Ponsioen, Cyriel Y, Prescott, Natalie J, Raychaudhuri, Soumya, Rieder, Florian, Rioux, John D, Ripke, Stephan, Russell, Richard K, Sanderson, Jeremy D, Satsangi, Jack, Schreiber, Stefan, Philip Schumm, L, Scott, Regan, Silverberg, Mark S, Simms, Lisa A, Spain, Sarah L, Sventoraityte, Jurgita, Torkvist, Leif, Tremelling, Mark, Vasiliauskas, Eric, Vermeire, Severine, Walters, Thomas, Wang, Kai, Wang, Ming-Hsi, Wei, Zhi, Winkelmann, Juliane, Zhang, Clarence K, Zhang, Wei, Zhao, Zhen Z
Published in Gut (01.11.2023)
Published in Gut (01.11.2023)
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An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age‐Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure
Hallam, Dean, Collin, Joseph, Bojic, Sanja, Chichagova, Valeria, Buskin, Adriana, Xu, Yaobo, Lafage, Lucia, Otten, Elsje. G., Anyfantis, George, Mellough, Carla, Przyborski, Stefan, Alharthi, Sameer, Korolchuk, Viktor, Lotery, Andrew, Saretzki, Gabriele, McKibbin, Martin, Armstrong, Lyle, Steel, David, Kavanagh, David, Lako, Majlinda
Published in Stem cells (Dayton, Ohio) (01.11.2017)
Published in Stem cells (Dayton, Ohio) (01.11.2017)
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A potent complement factor C3–specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement
Jensen, Rasmus K., Pihl, Rasmus, Gadeberg, Trine A.F., Jensen, Jan K., Andersen, Kasper R., Thiel, Steffen, Laursen, Nick S., Andersen, Gregers R.
Published in The Journal of biological chemistry (27.04.2018)
Published in The Journal of biological chemistry (27.04.2018)
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Functional expression of complement factor I following AAV-mediated gene delivery in the retina of mice and human cells
Dreismann, Anna K., McClements, Michelle E., Barnard, Alun R., Orhan, Elise, Hughes, Jane P., Lachmann, Peter J., MacLaren, Robert E.
Published in Gene therapy (01.05.2021)
Published in Gene therapy (01.05.2021)
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Elevated plasma concentration of complement factor C5 is associated with risk of future venous thromboembolism
Skjeflo, Espen Waage, Brækkan, Sigrid Kufaas, Ludviksen, Judith Krey, Snir, Omri, Hindberg, Kristian, Mollnes, Tom Eirik, Hansen, John-Bjarne
Published in Blood (25.11.2021)
Published in Blood (25.11.2021)
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Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids
Shaw, Peter X, Zhang, Li, Zhang, Ming, Du, Hongjun, Zhao, Ling, Lee, Clara, Grob, Seanna, Lim, Siok Lam, Hughes, Guy, Lee, Janet, Bedell, Matthew, Nelson, Mark H, Lu, Fang, Krupa, Martin, Luo, Jing, Ouyang, Hong, Tu, Zhidan, Su, Zhiguang, Zhu, Jin, Wei, Xinran, Feng, Zishan, Duan, Yaou, Yang, Zhenglin, Ferreyra, Henry, Bartsch, Dirk-Uwe, Kozak, Igor, Zhang, Liangfang, Lin, Feng, Sun, Hui, Feng, Hong, Zhang, Kang
Published in Proceedings of the National Academy of Sciences - PNAS (21.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (21.08.2012)
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Comprehensive functional characterization of complement factor I rare variant genotypes identified in the SCOPE geographic atrophy cohort
Hallam, Thomas M., Andreadi, Anneliza, Sharp, Scott J., Brocklebank, Vicky, Gardenal, Emanuela, Dreismann, Anna, Arora, Rashi, Dennis, Marcus, Flaxel, Christina, Hall, Edward, Hoyng, Carel, Charbel Issa, Peter, Leveziel, Nicolas, Molnár, Fanni, Navarro, Rafael, Schneiderman, Todd, Steel, David, Tadayoni, Ramin, Tezel, Tongalp, Weber, Michel, Lotery, Andrew J., Marchbank, Kevin J., Harris, Claire L., Jones, Amy V., Kavanagh, David
Published in The Journal of biological chemistry (01.07.2024)
Published in The Journal of biological chemistry (01.07.2024)
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Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications
Hageman, Gregory S, Hancox, Lisa S, Taiber, Andrew J, Gehrs, Karen M, Anderson, Don H, Johnson, Lincoln V, Radeke, Monte J, Kavanagh, David, Richards, Anna, Atkinson, John, Meri, Seppo, Bergeron, Julie, Zernant, Jana, Merriam, Joanna, Gold, Bert, Allikmets, Rando, Dean, Michael
Published in Annals of medicine (Helsinki) (2006)
Published in Annals of medicine (Helsinki) (2006)
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Evaluation of the cytochrome P450 2C19 and 3A4 inhibition potential of the complement factor 5a receptor 1 antagonist ACT‐1014‐6470 in vitro and in vivo
Anliker‐Ort, Marion, Dingemanse, Jasper, Delahaye, Stephane, Janů, Luboš, Anker, John, Berger, Benjamin, Kaufmann, Priska
Published in Clinical and translational science (01.07.2023)
Published in Clinical and translational science (01.07.2023)
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Alterations of Choroidal Blood Flow Regulation in Young Healthy Subjects with Complement Factor H Polymorphism
Told, Reinhard, Palkovits, Stefan, Haslacher, Helmuth, Frantal, Sophie, Schmidl, Doreen, Boltz, Agnes, Lasta, Michael, Kaya, Semira, Werkmeister, René M., Garhöfer, Gerhard, Schmetterer, Leopold
Published in PloS one (15.04.2013)
Published in PloS one (15.04.2013)
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