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Modulating the complement system through epitope-specific inhibition by complement C3 inhibitors
Chen, Zhidong, Wang, Mingshuang, Duan, Wenqian, Xia, Yi, Liu, Huiqin, Qian, Feng
Published in The Journal of biological chemistry (01.03.2025)
Published in The Journal of biological chemistry (01.03.2025)
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Blockade of HLA Antibody-Triggered Classical Complement Activation in Sera From Subjects Dosed With the Anti-C1s Monoclonal Antibody TNT009-Results from a Randomized First-in-Human Phase 1 Trial
Mühlbacher, Jakob, Jilma, Bernd, Wahrmann, Markus, Bartko, Johann, Eskandary, Farsad, Schörgenhofer, Christian, Schwameis, Michael, Parry, Graham C, Gilbert, James C, Panicker, Sandip, Böhmig, Georg A
Published in Transplantation (01.10.2017)
Published in Transplantation (01.10.2017)
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A phase I/II placebo-controlled trial of C1-inhibitor for prevention of antibody-mediated rejection in HLA sensitized patients
Vo, Ashley A, Zeevi, Adriana, Choi, Jua, Cisneros, Kristen, Toyoda, Mieko, Kahwaji, Joseph, Peng, Alice, Villicana, Rafael, Puliyanda, Dechu, Reinsmoen, Nancy, Haas, Mark, Jordan, Stanley C
Published in Transplantation (01.02.2015)
Published in Transplantation (01.02.2015)
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Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation
von Zur-Mühlen, Bengt, Lundgren, Torbjörn, Bayman, Levent, Berne, Christian, Bridges, Nancy, Eggerman, Thomas, Foss, Aksel, Goldstein, Julia, Jenssen, Trond, Jorns, Carl, Morrison, Yvonne, Rydén, Mikael, Schwieger, Traci, Tufveson, Gunnar, Nilsson, Bo, Korsgren, Olle
Published in Transplantation (01.03.2019)
Published in Transplantation (01.03.2019)
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Complement therapeutics meets nanomedicine: overcoming human complement activation and leukocyte uptake of nanomedicines with soluble domains of CD55
Gifford, Geoffrey, Vu, Vivian P., Banda, Nirmal K., Holers, V. Michael, Wang, Guankui, Groman, Ernest V., Backos, Donald, Scheinman, Robert, Moghimi, S. Moein, Simberg, Dmitri
Published in Journal of controlled release (28.05.2019)
Published in Journal of controlled release (28.05.2019)
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A monoclonal antibody targeting amyloid β (Aβ) restores complement factor I bioactivity: Potential implications in age-related macular degeneration and Alzheimer’s disease
Lashkari, Kameran, Teague, Gianna, Chen, Hong, Lin, Yong-Qing, Kumar, Sanjay, McLaughlin, Megan M., López, Francisco J.
Published in PloS one (21.05.2018)
Published in PloS one (21.05.2018)
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Mechanistic Understanding for the Greater Sensitivity of Monkeys to Antisense Oligonucleotide–Mediated Complement Activation Compared with Humans
Shen, Lijiang, Frazer-Abel, Ashley, Reynolds, Paul R., Giclas, Patricia C., Chappell, Alfred, Pangburn, Michael K., Younis, Husam, Henry, Scott P.
Published in The Journal of pharmacology and experimental therapeutics (01.12.2014)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2014)
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Fibrin nanoparticles as Possible vehicles for drug delivery
Vedakumari, Weslen S., Prabu, Periyathambi, Babu, Saravana C., Sastry, Thotapalli P.
Published in Biochimica et biophysica acta (01.08.2013)
Published in Biochimica et biophysica acta (01.08.2013)
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Methylation of the phosphate oxygen moiety of phospholipid-methoxy(polyethylene glycol) conjugate prevents PEGylated liposome-mediated complement activation and anaphylatoxin production
Moghimi, S. Moein, Hamad, Islam, Andresen, Thomas L, Jørgensen, Kent, Szebeni, Janos
Published in The FASEB journal (01.12.2006)
Published in The FASEB journal (01.12.2006)
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Lutein supplementation leads to decreased soluble complement membrane attack complex sC5b‐9 plasma levels
Tian, Yuan, Kijlstra, Aize, Veen, Rob L. P., Makridaki, Maria, Murray, Ian J., Berendschot, Tos T. J. M.
Published in Acta ophthalmologica (Oxford, England) (01.03.2015)
Published in Acta ophthalmologica (Oxford, England) (01.03.2015)
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The tainted heparin story: an update
Guerrini, Marco, Shriver, Zachary, Bisio, Antonella, Naggi, Annamaria, Casu, Benito, Sasisekharan, Ram, Torri, Giangiacomo
Published in Thrombosis and haemostasis (01.11.2009)
Published in Thrombosis and haemostasis (01.11.2009)
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Complement Activation in Patients With Congestive Heart Failure: Effect of High-Dose Intravenous Immunoglobulin Treatment
Aukrust, Pål, Gullestad, Lars, Lappegård, Knut T., Ueland, Thor, Aass, Halfdan, Wikeby, Lisbeth, Simonsen, Svein, Frøland, Stig S., Mollnes, Tom E.
Published in Circulation (New York, N.Y.) (25.09.2001)
Published in Circulation (New York, N.Y.) (25.09.2001)
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Randomized Safety Studies of Intravenous Perflubron Emulsion. II. Effects on Immune Function in Healthy Volunteers
Noveck, Robert J., Shannon, E. J., Leese, Phillip T., Shorr, Jolene S., Flaim, Kathryn E., Keipert, Peter E., Woods, Catherine M.
Published in Anesthesia and analgesia (01.10.2000)
Published in Anesthesia and analgesia (01.10.2000)
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