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Published in Nature (London) (30.09.2021)
Published in Nature (London) (30.09.2021)
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Potent and selective inhibitors of Helicobacter pylori glutamate racemase (MurI): Pyridodiazepine amines
Geng, Bolin, Basarab, Gregory, Comita-Prevoir, Janelle, Gowravaram, Madhusudhan, Hill, Pamela, Kiely, Andrew, Loch, James, MacPherson, Lawrence, Morningstar, Marshall, Mullen, George, Osimboni, Ekundayo, Satz, Alexander, Eyermann, Charles, Lundqvist, Tomas
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
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BETA-LACTAMASE INHIBITOR COMPOUNDS
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Year of Publication 02.06.2023
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Year of Publication 02.06.2023
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COMITA PREVOIR JANELLE, GULER SATENIG, DURAND REVILLE THOMAS FRANCOIS, TOMMASI RUBEN, SYLVESTER MARK, ROMERO JAN, WU XIAOYUN, VELEZ VEGA CAMILO, ZHANG JING
Year of Publication 15.01.2020
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Year of Publication 15.01.2020
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베타-락타마제 억제제 화합물
WU FRANK, COMITA PREVOIR JANELLE, GAUTHIER LISE, O'DONNELL JOHN, DURAND REVILLE THOMAS FRANCOIS, MOSS BILL, TOMMASI RUBEN, BASARAB GREGORY S, ROMERO JAN, WU XIAOYUN, VERHEIJEN JEROEN CUNERA, ZHANG JING
Year of Publication 26.04.2019
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Year of Publication 26.04.2019
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Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C, and D Serine β‑Lactamases
Durand-Réville, Thomas F, Comita-Prevoir, Janelle, Zhang, Jing, Wu, Xiaoyun, May-Dracka, Tricia L, Romero, Jan Antoinette C, Wu, Frank, Chen, April, Shapiro, Adam B, Carter, Nicole M, McLeod, Sarah M, Giacobbe, Robert A, Verheijen, Jeroen C, Lahiri, Sushmita D, Sacco, Michael D, Chen, Yu, O’Donnell, John P, Miller, Alita A, Mueller, John P, Tommasi, Rubén A
Published in Journal of medicinal chemistry (12.11.2020)
Published in Journal of medicinal chemistry (12.11.2020)
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ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii
Durand-Réville, Thomas F., Guler, Satenig, Comita-Prevoir, Janelle, Chen, Brendan, Bifulco, Neil, Huynh, Hoan, Lahiri, Sushmita, Shapiro, Adam B., McLeod, Sarah M., Carter, Nicole M., Moussa, Samir H., Velez-Vega, Camilo, Olivier, Nelson B., McLaughlin, Robert, Gao, Ning, Thresher, Jason, Palmer, Tiffany, Andrews, Beth, Giacobbe, Robert A., Newman, Joseph V., Ehmann, David E., de Jonge, Boudewijn, O'Donnell, John, Mueller, John P., Tommasi, Rubén A., Miller, Alita A.
Published in Nature microbiology (30.06.2017)
Published in Nature microbiology (30.06.2017)
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Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced p K a : Antibacterial Agents with an Improved Safety Profile
Reck, Folkert, Alm, Richard A., Brassil, Patrick, Newman, Joseph V., Ciaccio, Paul, McNulty, John, Barthlow, Herbert, Goteti, Kosalaram, Breen, John, Comita-Prevoir, Janelle, Cronin, Mark, Ehmann, David E., Geng, Bolin, Godfrey, Andrew Aydon, Fisher, Stewart L.
Published in Journal of medicinal chemistry (09.08.2012)
Published in Journal of medicinal chemistry (09.08.2012)
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Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II: Broad-Spectrum Antibacterial Agents with Reduced hERG Activity
Reck, Folkert, Alm, Richard, Brassil, Patrick, Newman, Joseph, DeJonge, Boudewijn, Eyermann, Charles J, Breault, Gloria, Breen, John, Comita-Prevoir, Janelle, Cronin, Mark, Davis, Hajnalka, Ehmann, David, Galullo, Vincent, Geng, Bolin, Grebe, Tyler, Morningstar, Marshall, Walker, Phil, Hayter, Barry, Fisher, Stewart
Published in Journal of medicinal chemistry (24.11.2011)
Published in Journal of medicinal chemistry (24.11.2011)
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Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced pK a: Antibacterial Agents with an Improved Safety Profile
Reck, Folkert, Alm, Richard A, Brassil, Patrick, Newman, Joseph V, Ciaccio, Paul, McNulty, John, Barthlow, Herbert, Goteti, Kosalaram, Breen, John, Comita-Prevoir, Janelle, Cronin, Mark, Ehmann, David E, Geng, Bolin, Godfrey, Andrew Aydon, Fisher, Stewart L
Published in Journal of medicinal chemistry (09.08.2012)
Published in Journal of medicinal chemistry (09.08.2012)
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N-Hydroxyformamide LpxC inhibitors, their in vivo efficacy in a mouse Escherichia coli infection model, and their safety in a rat hemodynamic assay
Furuya, Takeru, Shapiro, Adam B., Comita-Prevoir, Janelle, Kuenstner, Eric J., Zhang, Jing, Ribe, Seth D., Chen, April, Hines, Daniel, Moussa, Samir H., Carter, Nicole M., Sylvester, Mark A., Romero, Jan A.C., Vega, Camilo V., Sacco, Michael D., Chen, Yu, O'Donnell, John P., Durand-Reville, Thomas F., Miller, Alita A., Tommasi, Ruben A.
Published in Bioorganic & medicinal chemistry (15.12.2020)
Published in Bioorganic & medicinal chemistry (15.12.2020)
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HETEROBICYCLIC COMPOUNDS AS BETA-LACTAMASE INHIBITORS
COMITA PREVOIR JANELLE, GULER SATENIG, WU YE, HUYNH HOAN, CHEN BRENDAN, BIFULCO NEIL, ZHAO LIANG, DURAND REVILLE THOMAS, XIONG HUI, GENG BOLIN, DUSSAULT DAEMIAN, MCGUIRE HELEN, BIST SHANTA
Year of Publication 09.12.2014
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Year of Publication 09.12.2014
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Exploring Left-Hand-Side substitutions in the benzoxazinone series of 4-amino-piperidine bacterial type IIa topoisomerase inhibitors
Geng, Bolin, Comita-Prevoir, Janelle, Eyermann, Charles J., Reck, Folkert, Fisher, Stewart
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
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Optimization of physicochemical properties and safety profile of novel bacterial topoisomerase type II inhibitors (NBTIs) with activity against Pseudomonas aeruginosa
Reck, Folkert, Ehmann, David E., Dougherty, Thomas J., Newman, Joseph V., Hopkins, Sussie, Stone, Gregory, Agrawal, Nikunj, Ciaccio, Paul, McNulty, John, Barthlow, Herbert, O’Donnell, Jennifer, Goteti, Kosalaram, Breen, John, Comita-Prevoir, Janelle, Cornebise, Mark, Cronin, Mark, Eyermann, Charles J., Geng, Bolin, Carr, Greg R., Pandarinathan, Lakshmipathi, Tang, Xuejun, Cottone, Andrew, Zhao, Liang, Bezdenejnih-Snyder, Natascha
Published in Bioorganic & medicinal chemistry (01.10.2014)
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Exploring 8-benzyl pteridine-6,7-diones as inhibitors of glutamate racemase (Murl) in Gram-positive bacteria
BREAULT, Gloria A, COMITA-PREVOIR, Janelle, EYERMANN, Charles J, GENG, Bolin, PETRICHKO, Randy, DOIG, Peter, GORSETH, Elise, NOONAN, Brian
Published in Bioorganic & medicinal chemistry (01.12.2008)
Published in Bioorganic & medicinal chemistry (01.12.2008)
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Exploring 9-benzyl purines as inhibitors of glutamate racemase (MurI) in Gram-positive bacteria
Geng, Bolin, Breault, Gloria, Comita-Prevoir, Janelle, Petrichko, Randy, Eyermann, Charles, Lundqvist, Tomas, Doig, Peter, Gorseth, Elise, Noonan, Brian
Published in Bioorganic & medicinal chemistry (01.08.2008)
Published in Bioorganic & medicinal chemistry (01.08.2008)
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ETX2514 is a broad-spectrum [beta]-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii
Durand-réville, Thomas F, Guler, Satenig, Comita-prevoir, Janelle, Chen, Brendan, Bifulco, Neil, Huynh, Hoan, Lahiri, Sushmita, Shapiro, Adam B, Mcleod, Sarah M, Carter, Nicole M, Moussa, Samir H, Velez-vega, Camilo, Olivier, Nelson B, Mclaughlin, Robert, Gao, Ning, Thresher, Jason, Palmer, Tiffany, Andrews, Beth, Giacobbe, Robert A, Newman, Joseph V, Ehmann, David E, De Jonge, Boudewijn, O'donnell, John, Mueller, John P, Tommasi, Rubén A, Miller, Alita A
Published in Nature microbiology (01.09.2017)
Published in Nature microbiology (01.09.2017)
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COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS
ZHANG, JING, VELEZ-VEGA, CAMILO, DURAND-REVILLE, THOMAS FRANCOIS, ROMERO, JAN, WU, XIAOYUN, SYLVESTER, MARK, GULER, SATENIG, COMITA-PREVOIR, JANELLE, TOMMASI, RUBEN
Year of Publication 21.02.2024
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Year of Publication 21.02.2024
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COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS
TOMMASI Ruben, WU Xiaoyun, ZHANG Jing, DURAND-REVILLE Thomas Francois, VELEZ-VEGA Camilo, GULER Satenig, COMITA-PREVOIR Janelle, ROMERO Jan, SYLVESTER Mark
Year of Publication 31.05.2022
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Year of Publication 31.05.2022
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