Search Results - "Combes, R.D" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

722 A critique of the European commission's proposals for registering new & existing chemicals

722 A critique of the European commission's proposals for registering new & existing chemicals

by Combes, R.D.
Published in Toxicology letters (01.09.2003)

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Journal Article

Why 'suitable' in vitro methods, as defined in the final EU REACH legislation, are an inappropriate basis for risk assessment

Why 'suitable' in vitro methods, as defined in the final EU REACH legislation, are an inappropriate basis for risk assessment

by Combes, R.D
Published in Alternatives to laboratory animals (01.05.2007)

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scientific and animal welfare assessment of the OECD health effects test guidelines for the safety testing of chemicals under the European Union REACH system

scientific and animal welfare assessment of the OECD health effects test guidelines for the safety testing of chemicals under the European Union REACH system

by Combes, R.D, Gaunt, I, Balls, M
Published in Alternatives to laboratory animals (01.09.2004)

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Topological structural alerts modulations of mammalian cell mutagenicity for halogenated derivatives

Topological structural alerts modulations of mammalian cell mutagenicity for halogenated derivatives

by Pérez-Garrido, A., Girón-Rodríguez, F., Morales Helguera, A., Borges, F., Combes, R.D.
Published in SAR and QSAR in environmental research (01.01.2014)

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Quantitative structure-activity relationship modelling of the carcinogenic risk of nitroso compounds using regression analysis and the TOPS-MODE approach

Quantitative structure-activity relationship modelling of the carcinogenic risk of nitroso compounds using regression analysis and the TOPS-MODE approach

by Helguera, A.M., Pérez-Machado, G., Cordeiro, M.N.D.S., Combes, R.D.
Published in SAR and QSAR in environmental research (01.04.2010)

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Early microdose drug studies in human volunteers can minimise animal testing: Proceedings of a workshop organised by Volunteers in Research and Testing

Early microdose drug studies in human volunteers can minimise animal testing: Proceedings of a workshop organised by Volunteers in Research and Testing

by Combes, R.D, Berridge, T, Connelly, J, Eve, M.D, Garner, R.C, Toon, S, Wilcox, P
Published in European journal of pharmaceutical sciences (01.05.2003)

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$Characterization of a microsomal fraction from rat small intestine for metabolic activation of some promutagens$

Characterization of a microsomal fraction from rat small intestine for metabolic activation of some promutagens

by Walters, J M, Combes, R D
Published in Carcinogenesis (New York) (01.10.1985)

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Journal Article

The use of structure–activity relationships and markers of cell toxicity to detect non-genotoxic carcinogens

The use of structure–activity relationships and markers of cell toxicity to detect non-genotoxic carcinogens

by Combes, R.D
Published in Toxicology in vitro (01.08.2000)

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Mutagenicity studies of urine and faecal samples from rats treated orally with the food colourings brown FK and Red 2G

Mutagenicity studies of urine and faecal samples from rats treated orally with the food colourings brown FK and Red 2G

by Edwards, C.N., Combes, R.D.
Published in Food and chemical toxicology (1984)

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OECD health effects test guidelines: a challenge to the sincerity of commitment to the three Rs

OECD health effects test guidelines: a challenge to the sincerity of commitment to the three Rs

by Balls, M, Combes, R.D
Published in Alternatives to laboratory animals (01.02.2006)

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case for taking account of metabolism when testing for potential endocrine disruptors in vitro

case for taking account of metabolism when testing for potential endocrine disruptors in vitro

by Combes, R.D
Published in Alternatives to laboratory animals (01.06.2004)

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Peer review of validation studies: an assessment of the role of the OECD by reference to the validation of the uterotrophic assay for endocrine disruptors

Peer review of validation studies: an assessment of the role of the OECD by reference to the validation of the uterotrophic assay for endocrine disruptors

by Combes, R.D
Published in Alternatives to laboratory animals (01.06.2004)

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use of non-human primates in biological and medical research: Evidence submitted by FRAME to the Academy of Medical Sciences/Medical Research Council/Royal Society/Wellcome Trust Working Group

use of non-human primates in biological and medical research: Evidence submitted by FRAME to the Academy of Medical Sciences/Medical Research Council/Royal Society/Wellcome Trust Working Group

by Bhogal, N, Hudson, M, Balls, M, Combes, R.D
Published in Alternatives to laboratory animals (01.10.2005)

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current OECD health effects test guidelines are in urgent need of revision

current OECD health effects test guidelines are in urgent need of revision

by Combes, R.D
Published in Alternatives to laboratory animals (01.11.2004)

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Recent and promising alternatives to animal experiments [genotoxicity]

Recent and promising alternatives to animal experiments [genotoxicity]

by Combes, R.D
Published in Scandinavian journal of laboratory animal science (1995)

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Studies on the genotoxicity of the food colour Brown FK and its component dyes using bacterial assays

Studies on the genotoxicity of the food colour Brown FK and its component dyes using bacterial assays

by Haveland-Smith, R.B., Combes, R.D.
Published in Mutation research (01.01.1982)

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evaluation of the Drosophila zeste somatic eye mutation test for the detection of genotoxic azo dyes and an aromatic amine

evaluation of the Drosophila zeste somatic eye mutation test for the detection of genotoxic azo dyes and an aromatic amine

by Edwards, C.N, Combes, R.D
Published in Mutation research (1981)

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Studies on the mutagenicity of commercial preparations of the food colour Red 2G after purification or oxidation

Studies on the mutagenicity of commercial preparations of the food colour Red 2G after purification or oxidation

by Edwards, C.N., Combes, R.D.
Published in Mutation Research/Genetic Toxicology (01.01.1983)

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Summary of Discussion: In Vitro Models for Investigation of Chronic Toxicity and Reversibility

Summary of Discussion: In Vitro Models for Investigation of Chronic Toxicity and Reversibility

by Combes, R.D
Published in Toxicology in vitro (01.08.1999)

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Journal Article

Screening of food dyes for genotoxic activity

Screening of food dyes for genotoxic activity

by Haveland-Smith, R.B., Combes, R.D.
Published in Food and cosmetics toxicology (01.01.1980)

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