Chronic lymphocytic leukemia: from molecular pathogenesis to novel therapeutic strategies
Delgado, Julio, Nadeu, Ferran, Colomer, Dolors, Campo, Elias
Published in Haematologica (Roma) (01.09.2020)
Published in Haematologica (Roma) (01.09.2020)
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The Bruton Tyrosine Kinase (BTK) Inhibitor Acalabrutinib Demonstrates Potent On-Target Effects and Efficacy in Two Mouse Models of Chronic Lymphocytic Leukemia
Herman, Sarah E M, Montraveta, Arnau, Niemann, Carsten U, Mora-Jensen, Helena, Gulrajani, Michael, Krantz, Fanny, Mantel, Rose, Smith, Lisa L, McClanahan, Fabienne, Harrington, Bonnie K, Colomer, Dolors, Covey, Todd, Byrd, John C, Izumi, Raquel, Kaptein, Allard, Ulrich, Roger, Johnson, Amy J, Lannutti, Brian J, Wiestner, Adrian, Woyach, Jennifer A
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Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation
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Published in Nature communications (28.01.2021)
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The receptor of the colony-stimulating factor-1 (CSF-1R) is a novel prognostic factor and therapeutic target in follicular lymphoma
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Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosis
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Published in Blood (14.08.2014)
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Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia
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Published in Blood (28.04.2016)
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Beà, Sílvia, Valdés-Mas, Rafael, Navarro, Alba, Salaverria, Itziar, Martín-Garcia, David, Jares, Pedro, Giné, Eva, Pinyol, Magda, Royo, Cristina, Nadeu, Ferran, Conde, Laura, Juan, Manel, Clot, Guillem, Vizán, Pedro, Di Croce, Luciano, Puente, Diana A., López-Guerra, Mónica, Moros, Alexandra, Roue, Gael, Aymerich, Marta, Villamor, Neus, Colomo, Lluís, Martínez, Antonio, Valera, Alexandra, Martín-Subero, José I., Amador, Virginia, Hernández, Luis, Rozman, Maria, Enjuanes, Anna, Forcada, Pilar, Muntañola, Ana, Hartmann, Elena M., Calasanz, María J., Rosenwald, Andreas, Ott, German, Hernández-Rivas, Jesús M., Klapper, Wolfram, Siebert, Reiner, Wiestner, Adrian, Wilson, Wyndham H., Colomer, Dolors, López-Guillermo, Armando, López-Otín, Carlos, Puente, Xose S., Campo, Elías
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2013)
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EOMES is essential for antitumor activity of CD8+ T cells in chronic lymphocytic leukemia
Llaó-Cid, Laura, Roessner, Philipp M., Chapaprieta, Vicente, Öztürk, Selcen, Roider, Tobias, Bordas, Marie, Izcue, Ana, Colomer, Dolors, Dietrich, Sascha, Stilgenbauer, Stephan, Hanna, Bola, Martín-Subero, José Ignacio, Seiffert, Martina
Published in Leukemia (01.11.2021)
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IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms
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Published in Nature communications (07.07.2020)
Published in Nature communications (07.07.2020)
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Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia
Gimenez, Neus, Tripathi, Rupal, Giró, Ariadna, Rosich, Laia, López-Guerra, Mònica, López-Oreja, Irene, Playa-Albinyana, Heribert, Arenas, Fabian, Mas, José Manuel, Pérez-Galán, Patricia, Delgado, Julio, Campo, Elias, Farrés, Judith, Colomer, Dolors
Published in Scientific reports (17.12.2020)
Published in Scientific reports (17.12.2020)
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EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4+ T cells in chronic lymphocytic leukemia
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Published in Leukemia (01.08.2021)
Published in Leukemia (01.08.2021)
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Targeting IRAK4 disrupts inflammatory pathways and delays tumor development in chronic lymphocytic leukemia
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Published in Leukemia (01.01.2020)
Published in Leukemia (01.01.2020)
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Mutations in the RAS-BRAF-MAPK-ERK pathway define a specific subgroup of patients with adverse clinical features and provide new therapeutic options in chronic lymphocytic leukemia
Giménez, Neus, Martínez-Trillos, Alejandra, Montraveta, Arnau, Lopez-Guerra, Mónica, Rosich, Laia, Nadeu, Ferran, Valero, Juan G, Aymerich, Marta, Magnano, Laura, Rozman, Maria, Matutes, Estella, Delgado, Julio, Baumann, Tycho, Gine, Eva, González, Marcos, Alcoceba, Miguel, Terol, M José, Navarro, Blanca, Colado, Enrique, Payer, Angel R, Puente, Xose S, López-Otín, Carlos, Lopez-Guillermo, Armando, Campo, Elias, Colomer, Dolors, Villamor, Neus
Published in Haematologica (Roma) (01.03.2019)
Published in Haematologica (Roma) (01.03.2019)
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Sampling time-dependent artifacts in single-cell genomics studies
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Published in Genome Biology (11.05.2020)
Published in Genome Biology (11.05.2020)
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Molecular Subsets of Mantle Cell Lymphoma Defined by the IGHV Mutational Status and SOX11 Expression Have Distinct Biologic and Clinical Features
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Published in Cancer research (Chicago, Ill.) (15.10.2012)
Published in Cancer research (Chicago, Ill.) (15.10.2012)
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Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia
Ferreira, Pedro G, Jares, Pedro, Rico, Daniel, Gómez-López, Gonzalo, Martínez-Trillos, Alejandra, Villamor, Neus, Ecker, Simone, González-Pérez, Abel, Knowles, David G, Monlong, Jean, Johnson, Rory, Quesada, Victor, Djebali, Sarah, Papasaikas, Panagiotis, López-Guerra, Mónica, Colomer, Dolors, Royo, Cristina, Cazorla, Maite, Pinyol, Magda, Clot, Guillem, Aymerich, Marta, Rozman, Maria, Kulis, Marta, Tamborero, David, Gouin, Anaïs, Blanc, Julie, Gut, Marta, Gut, Ivo, Puente, Xose S, Pisano, David G, Martin-Subero, José Ignacio, López-Bigas, Nuria, López-Guillermo, Armando, Valencia, Alfonso, López-Otín, Carlos, Campo, Elías, Guigó, Roderic
Published in Genome research (01.02.2014)
Published in Genome research (01.02.2014)
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Genomic and Gene Expression Profiling Defines Indolent Forms of Mantle Cell Lymphoma
FERNANDEZ, Verònica, SALAMERO, Olga, HERNANDEZ, Luis, AGOSTINELLI, Claudio, SARGENT, Rachel L, ROZMAN, Maria, AYMERICH, Marta, COLOMER, Dolors, VILLAMOR, Neus, SWERDLOW, Steven H, PILERI, Stefano A, BOSCH, Francesc, ESPINET, Blanca, PIRIS, Miguel A, MONTSERRAT, Emili, OTT, German, ROSENWALD, Andreas, LOPEZ-GUILLERMO, Armando, JARES, Pedro, SERRANO, Sergi, CAMPO, Elias, SOLE, Francesc, ROYO, Cristina, NAVARRO, Alba, CAMACHO, Francisca, BEA, Silvia, HARTMANN, Elena, AMADOR, Virginia
Published in Cancer research (Chicago, Ill.) (15.02.2010)
Published in Cancer research (Chicago, Ill.) (15.02.2010)
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Daratumumab displays in vitro and in vivo anti-tumor activity in models of B-cell non-Hodgkin lymphoma and improves responses to standard chemo-immunotherapy regimens
Vidal-Crespo, Anna, Matas-Céspedes, Alba, Rodriguez, Vanina, Rossi, Cédric, Valero, Juan G, Serrat, Neus, Sanjuan-Pla, Alejandra, Menéndez, Pablo, Roué, Gaël, López-Guillermo, Armando, Giné, Eva, Campo, Elías, Colomer, Dolors, Bezombes, Christine, van Bueren, Jeroen Lammerts, Chiu, Christopher, Doshi, Parul, Pérez-Galán, Patricia
Published in Haematologica (Roma) (01.04.2020)
Published in Haematologica (Roma) (01.04.2020)
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Novel Tools for Diagnosis and Monitoring of AML
Guijarro, Francesca, Garrote, Marta, Villamor, Neus, Colomer, Dolors, Esteve, Jordi, López-Guerra, Mónica
Published in Current oncology (Toronto) (23.05.2023)
Published in Current oncology (Toronto) (23.05.2023)
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