Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells
Robson, J. L., Thorn, R. M. S., Williams, A. C., Collard, T. J., Qualtrough, D.
Published in Scientific reports (12.10.2023)
Published in Scientific reports (12.10.2023)
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β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: a role in the chemopreventive efficacy of aspirin?
SMARTT, Hjm, GREENHOUGH, A, ORDONEZ-MORAN, P, AI-KHARUSI, M, COLLARD, T. J, MARIADASON, J. M, HUELSKEN, J, WILLIAMS, A. C, PARASKEVA, C
Published in British journal of cancer (23.10.2012)
Published in British journal of cancer (23.10.2012)
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LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity
Morgan, R G, Mortensson, E, Legge, D N, Gupta, B, Collard, T J, Greenhough, A, Williams, A C
Published in British journal of cancer (20.02.2018)
Published in British journal of cancer (20.02.2018)
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Transcriptional upregulation of the insulin-like growth factor binding protein IGFBP-3 by sodium butyrate increases IGF-independent apoptosis in human colonic adenoma-derived epithelial cells
Collard, T.J., Guy, M., Butt, A.J., Perks, C.M., Holly, J.M.P., Paraskeva, C., Williams, A.C.
Published in Carcinogenesis (New York) (01.03.2003)
Published in Carcinogenesis (New York) (01.03.2003)
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Increased p53-dependent apoptosis by the insulin-like growth factor binding protein IGFBP-3 in human colonic adenoma-derived cells
WILLIAMS, A. C, COLLARD, T. J, PERKS, C. M, NEWCOMB, P, MOORGHEN, M, HOLLY, J. M. P, PARASKEVA, C
Published in Cancer research (Chicago, Ill.) (2000)
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Published in Cancer research (Chicago, Ill.) (2000)
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Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells
Morgan, R G, Molnár, E, Jones, R F, Collard, T J, Lane, J D, Greenhough, A, Paraskeva, C, Williams, A C
Published in British journal of cancer (17.02.2015)
Published in British journal of cancer (17.02.2015)
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BAG-1 interacts with the p50-p50 homodimeric NF-[kappa]B complex: implications for colorectal carcinogenesis
Southern, S L, Collard, T J, Urban, B C, Skeen, V R, Smartt, H J, Hague, A, Oakley, F, Townsend, P A, Perkins, N D, Paraskeva, C, Williams, A C
Published in Oncogene (31.05.2012)
Published in Oncogene (31.05.2012)
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Transcriptional down-regulation of the retinoblastoma protein is associated with differentiation and apoptosis in human colorectal epithelial cells
GUY, M, MOORGHEN, M, BOND, J. A, COLLARD, T. J, PARASKEVA, C, WILLIAMS, A. C
Published in British journal of cancer (01.02.2001)
Published in British journal of cancer (01.02.2001)
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Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-κB
Williams, A C, Smartt, H, H-Zadeh, A M, MacFarlane, M, Paraskeva, C, Collard, T J
Published in Cell death and differentiation (01.01.2007)
Published in Cell death and differentiation (01.01.2007)
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BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis
Southern, S L, Collard, T J, Urban, B C, Skeen, V R, Smartt, H J, Hague, A, Oakley, F, Townsend, P A, Perkins, N D, Paraskeva, C, Williams, A C
Published in Oncogene (31.05.2012)
Published in Oncogene (31.05.2012)
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Mutant p53 is not fully dominant over endogenous wild type p53 in a colorectal adenoma cell line as demonstrated by induction of MDM2 protein and retention of a p53 dependent G1 arrest after gamma irradiation
Williams, A C, Miller, J C, Collard, T J, Bracey, T S, Cosulich, S, Paraskeva, C
Published in Oncogene (06.07.1995)
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Published in Oncogene (06.07.1995)
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The retinoblastoma protein interacts with Bag‐1 in human colonic adenoma and carcinoma derived cell lines
Arhel, Nathalie J., Packham, Graham, Townsend, Paul A., Collard, Tracey J., H‐Zadeh, Akram M., Sharp, Adam, Cutress, Ramsey I., Malik, Karim, Hague, Angela, Paraskeva, Chris, Williams, Ann C.
Published in International journal of cancer (01.09.2003)
Published in International journal of cancer (01.09.2003)
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BAG-1 suppresses expression of the key regulatory cytokine transforming growth factor [beta] (TGF-[beta]1) in colorectal tumour cells
Skeen, V R, Collard, T J, Southern, S L, Greenhough, A, Hague, A, Townsend, P A, Paraskeva, C, Williams, A C
Published in Oncogene (19.09.2013)
Published in Oncogene (19.09.2013)
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[beta]-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: a role in the chemopreventive efficacy of aspirin?
Smartt, H J M, Greenhough, A, Ordóñez-morán, P, Al-kharusi, M, Collard, T J, Mariadason, J M, Huelsken, J, Williams, A C, Paraskeva, C
Published in British journal of cancer (23.10.2012)
Published in British journal of cancer (23.10.2012)
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Transfection and expression of mutant p53 protein does not alter the in vivo or in vitro growth characteristics of the AA/C1 human adenoma derived cell line, including sensitivity to transforming growth factor-beta 1
Williams, A C, Browne, S J, Manning, A M, Daffada, P, Collard, T J, Paraskeva, C
Published in Oncogene (01.05.1994)
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Published in Oncogene (01.05.1994)
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The retinoblastoma protein (Rb) as an anti-apoptotic factor: expression of Rb is required for the anti-apoptotic function of BAG-1 protein in colorectal tumour cells
Collard, T J, Urban, B C, Patsos, H A, Hague, A, Townsend, P A, Paraskeva, C, Williams, A C
Published in Cell death & disease (11.10.2012)
Published in Cell death & disease (11.10.2012)
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Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-kappaB
Williams, A C, Smartt, H, H-Zadeh, A M, Macfarlane, M, Paraskeva, C, Collard, T J
Published in Cell death and differentiation (01.01.2007)
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Published in Cell death and differentiation (01.01.2007)
Journal Article
Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF- B
Williams, A C, Smartt, H, H-Zadeh, A M, MacFarlane, M, Paraskeva, C, Collard, T J
Published in Cell death and differentiation (01.01.2007)
Published in Cell death and differentiation (01.01.2007)
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