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Arimoto, Kei-ichiro, Löchte, Sara, Stoner, Samuel A, Burkart, Christoph, Zhang, Yue, Miyauchi, Sayuri, Wilmes, Stephan, Fan, Jun-Bao, Heinisch, Jürgen J, Li, Zhi, Yan, Ming, Pellegrini, Sandra, Colland, Frédéric, Piehler, Jacob, Zhang, Dong-Er
Published in Nature structural & molecular biology (01.03.2017)
Published in Nature structural & molecular biology (01.03.2017)
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Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia
Moujalled, Donia M., Pomilio, Giovanna, Ghiurau, Corina, Ivey, Adam, Salmon, Jessica, Rijal, Sewa, Macraild, Sarah, Zhang, Lan, Teh, Tse-Chieh, Tiong, Ing-Soo, Lan, Ping, Chanrion, Maia, Claperon, Audrey, Rocchetti, Francesca, Zichi, Adrien, Kraus-Berthier, Laurence, Wang, Youzhen, Halilovic, Ensar, Morris, Erick, Colland, Frédéric, Segal, David, Huang, David, Roberts, Andrew W., Maragno, Ana Leticia, Lessene, Guillaume, Geneste, Olivier, Wei, Andrew H.
Published in Leukemia (01.04.2019)
Published in Leukemia (01.04.2019)
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Discovery of S64315, a Potent and Selective Mcl‑1 Inhibitor
Szlavik, Zoltan, Csekei, Marton, Paczal, Attila, Szabo, Zoltan B, Sipos, Szabolcs, Radics, Gabor, Proszenyak, Agnes, Balint, Balazs, Murray, James, Davidson, James, Chen, Ijen, Dokurno, Pawel, Surgenor, Allan E, Daniels, Zoe Marie, Hubbard, Roderick E, Le Toumelin-Braizat, Gaëtane, Claperon, Audrey, Lysiak-Auvity, Gaëlle, Girard, Anne-Marie, Bruno, Alain, Chanrion, Maia, Colland, Frédéric, Maragno, Ana-Leticia, Demarles, Didier, Geneste, Olivier, Kotschy, Andras
Published in Journal of medicinal chemistry (25.11.2020)
Published in Journal of medicinal chemistry (25.11.2020)
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Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells
Colland, Frédéric, Formstecher, Etienne, Jacq, Xavier, Reverdy, Céline, Planquette, Cécile, Conrath, Susan, Trouplin, Virginie, Bianchi, Julie, Aushev, Vasily N, Camonis, Jacques, Calabrese, Alessandra, Borg-Capra, Catherine, Sippl, Wolfgang, Collura, Vincent, Boissy, Guillaume, Rain, Jean-Christophe, Guedat, Philippe, Delansorne, Rémi, Daviet, Laurent
Published in Molecular cancer therapeutics (01.08.2009)
Published in Molecular cancer therapeutics (01.08.2009)
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FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
Burgering, Boudewijn M.T, van der Horst, Armando, de Vries-Smits, Alida M.M, Brenkman, Arjan B, van Triest, Miranda H, van den Broek, Niels, Colland, Frédéric, Maurice, Madelon M
Published in Nature cell biology (01.10.2006)
Published in Nature cell biology (01.10.2006)
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Mst4 and Ezrin Induce Brush Borders Downstream of the Lkb1/Strad/Mo25 Polarization Complex
ten Klooster, Jean Paul, Jansen, Marnix, Yuan, Jin, Oorschot, Viola, Begthel, Harry, Di Giacomo, Valeria, Colland, Frédéric, de Koning, John, Maurice, Madelon M., Hornbeck, Peter, Clevers, Hans
Published in Developmental cell (01.04.2009)
Published in Developmental cell (01.04.2009)
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Listeria monocytogenes InlC protein interferes with innate immune responses by targeting the IκB kinase subunit IKKα
Gouin, Edith, Adib-Conquy, Minou, Balestrino, Damien, Nahori, Marie-Anne, Villiers, Véronique, Colland, Frédéric, Dramsi, Shaynoor, Dussurget, Olivier, Cossart, Pascale
Published in Proceedings of the National Academy of Sciences - PNAS (05.10.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (05.10.2010)
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Ubiquitin-specific proteases as cancer drug targets
Sippl, Wolfgang, Collura, Vincent, Colland, Fréédééric
Published in Future oncology (London, England) (01.05.2011)
Published in Future oncology (London, England) (01.05.2011)
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Development of Inducible Systems To Engineer Conditional Mutants of Essential Genes of Helicobacter pylori
Boneca, Ivo G, Ecobichon, Chantal, Chaput, Catherine, Mathieu, Aurélie, Guadagnini, Stéphanie, Prévost, Marie-Christine, Colland, Frédéric, Labigne, Agnès, de Reuse, Hilde
Published in Applied and Environmental Microbiology (01.04.2008)
Published in Applied and Environmental Microbiology (01.04.2008)
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Functional proteomics mapping of a human signaling pathway
Colland, Frédéric, Jacq, Xavier, Trouplin, Virginie, Mougin, Christelle, Groizeleau, Caroline, Hamburger, Alexandre, Meil, Alain, Wojcik, Jérôme, Legrain, Pierre, Gauthier, Jean-Michel
Published in Genome research (01.07.2004)
Published in Genome research (01.07.2004)
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Identification of PHRF1 as a Tumor Suppressor that Promotes the TGF-β Cytostatic Program through Selective Release of TGIF-Driven PML Inactivation
Ettahar, Asma, Ferrigno, Olivier, Zhang, Ming-Zhu, Ohnishi, Mutsuko, Ferrand, Nathalie, Prunier, Céline, Levy, Laurence, Bourgeade, Marie-Françoise, Bieche, Ivan, Romero, Damian G., Colland, Frédéric, Atfi, Azeddine
Published in Cell reports (Cambridge) (15.08.2013)
Published in Cell reports (Cambridge) (15.08.2013)
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Discovery of Specific Inhibitors of Human USP7/HAUSP Deubiquitinating Enzyme
Reverdy, Céline, Conrath, Susan, Lopez, Roman, Planquette, Cécile, Atmanene, Cédric, Collura, Vincent, Harpon, Jane, Battaglia, Véronique, Vivat, Valérie, Sippl, Wolfgang, Colland, Frédéric
Published in Chemistry & biology (20.04.2012)
Published in Chemistry & biology (20.04.2012)
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TGIF Governs a Feed-Forward Network that Empowers Wnt Signaling to Drive Mammary Tumorigenesis
Zhang, Ming-Zhu, Ferrigno, Olivier, Wang, Zhe, Ohnishi, Mutsuko, Prunier, Céline, Levy, Laurence, Razzaque, Mohammed, Horne, Williams C., Romero, Damian, Tzivion, Guri, Colland, Frédéric, Baron, Roland, Atfi, Azeddine
Published in Cancer cell (13.04.2015)
Published in Cancer cell (13.04.2015)
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disintegrin and metalloproteinase ADAM12 contributes to TGF-β signaling through interaction with the type II receptor
Atfi, Azeddine, Dumont, Emmanuelle, Colland, Frédéric, Bonnier, Dominique, L'Helgoualc'h, Annie, Prunier, Céline, Ferrand, Nathalie, Clément, Bruno, Wewer, Ulla M, Théret, Nathalie
Published in The Journal of cell biology (16.07.2007)
Published in The Journal of cell biology (16.07.2007)
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Synthesis and Biological Evaluation of 9-Oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile Analogues as Potential Inhibitors of Deubiquitinating Enzymes
Colombo, Matteo, Vallese, Stefania, Peretto, Ilaria, Jacq, Xavier, Rain, Jean-Christophe, Colland, Frédéric, Guedat, Philippe
Published in ChemMedChem (06.04.2010)
Published in ChemMedChem (06.04.2010)
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The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
Kotschy, András, Szlavik, Zoltán, Murray, James, Davidson, James, Maragno, Ana Leticia, Le Toumelin-Braizat, Gaëtane, Chanrion, Maïa, Kelly, Gemma L., Gong, Jia-Nan, Moujalled, Donia M., Bruno, Alain, Csekei, Márton, Paczal, Attila, Szabo, Zoltán B., Sipos, Szabolcs, Radics, Gábor, Proszenyak, Agnes, Balint, Balázs, Ondi, Levente, Blasko, Gábor, Robertson, Alan, Surgenor, Allan, Dokurno, Pawel, Chen, Ijen, Matassova, Natalia, Smith, Julia, Pedder, Christopher, Graham, Christopher, Studeny, Aurélie, Lysiak-Auvity, Gaëlle, Girard, Anne-Marie, Gravé, Fabienne, Segal, David, Riffkin, Chris D., Pomilio, Giovanna, Galbraith, Laura C. A., Aubrey, Brandon J., Brennan, Margs S., Herold, Marco J., Chang, Catherine, Guasconi, Ghislaine, Cauquil, Nicolas, Melchiore, Fabien, Guigal-Stephan, Nolwen, Lockhart, Brian, Colland, Frédéric, Hickman, John A., Roberts, Andrew W., Huang, David C. S., Wei, Andrew H., Strasser, Andreas, Lessene, Guillaume, Geneste, Olivier
Published in Nature (London) (27.10.2016)
Published in Nature (London) (27.10.2016)
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