Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing
Webb, James D, Coleman, Mathew L, Pugh, Christopher W
Published in Cellular and molecular life sciences : CMLS (01.11.2009)
Published in Cellular and molecular life sciences : CMLS (01.11.2009)
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Journal Article
The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens
Loenarz, Christoph, Coleman, Mathew L, Boleininger, Anna, Schierwater, Bernd, Holland, Peter W H, Ratcliffe, Peter J, Schofield, Christopher J
Published in EMBO reports (01.01.2011)
Published in EMBO reports (01.01.2011)
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Journal Article
Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1
Feng, Tianshu, Yamamoto, Atsushi, Wilkins, Sarah E., Sokolova, Elizaveta, Yates, Luke A., Münzel, Martin, Singh, Pooja, Hopkinson, Richard J., Fischer, Roman, Cockman, Matthew E., Shelley, Jake, Trudgian, David C., Schödel, Johannes, McCullagh, James S.O., Ge, Wei, Kessler, Benedikt M., Gilbert, Robert J., Frolova, Ludmila Y., Alkalaeva, Elena, Ratcliffe, Peter J., Schofield, Christopher J., Coleman, Mathew L.
Published in Molecular cell (20.02.2014)
Published in Molecular cell (20.02.2014)
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Journal Article
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
Singleton, Rachelle S., Liu-Yi, Phebee, Formenti, Fabio, Ge, Wei, Sekirnik, Rok, Fischer, Roman, Adam, Julie, Pollard, Patrick J., Wolf, Alexander, Thalhammer, Armin, Loenarz, Christoph, Flashman, Emily, Yamamoto, Atsushi, Coleman, Mathew L., Kessler, Benedikt M., Wappner, Pablo, Schofield, Christopher J., Ratcliffe, Peter J., Cockman, Matthew E.
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2014)
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Journal Article
Precisely Tuned Inhibition of HIF Prolyl Hydroxylases Is Key for Cardioprotection After Ischemia
Jatho, Aline, Zieseniss, Anke, Brechtel-Curth, Katja, Yamamoto, Atsushi, Coleman, Mathew L., Vergel Leon, Ana M., Biggs, Daniel, Davies, Ben, Pugh, Chris W., Ratcliffe, Peter J., Katschinski, Dörthe M.
Published in Circulation research (16.04.2021)
Published in Circulation research (16.04.2021)
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Journal Article
Systemic silencing of PHD2 causes reversible immune regulatory dysfunction
Yamamoto, Atsushi, Hester, Joanna, Macklin, Philip S, Kawai, Kento, Uchiyama, Masateru, Biggs, Daniel, Bishop, Tammie, Bull, Katherine, Cheng, Xiaotong, Cawthorne, Eleanor, Coleman, Mathew L, Crockford, Tanya L, Davies, Ben, Dow, Lukas E, Goldin, Rob, Kranc, Kamil, Kudo, Hiromi, Lawson, Hannah, McAuliffe, James, Milward, Kate, Scudamore, Cheryl L, Soilleux, Elizabeth, Issa, Fadi, Ratcliffe, Peter J, Pugh, Chris W
Published in The Journal of clinical investigation (01.09.2019)
Published in The Journal of clinical investigation (01.09.2019)
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Journal Article
Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pathway
Pillai, Meenu R, Mihi, Belgacem, Ishiwata, Kenji, Nakamura, Kiminori, Sakuragi, Naoya, Finkelstein, David B, McGargill, Maureen A, Nakayama, Toshinori, Ayabe, Tokiyoshi, Coleman, Mathew L, Bix, Mark
Published in PloS one (26.02.2019)
Published in PloS one (26.02.2019)
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Journal Article
RAS and RHO GTPases in G1-phase cell-cycle regulation
Olson, Michael F, Coleman, Mathew L, Marshall, Christopher J
Published in Nature reviews. Molecular cell biology (01.05.2004)
Published in Nature reviews. Molecular cell biology (01.05.2004)
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Journal Article
Impaired protein hydroxylase activity causes replication stress and developmental abnormalities in humans
Fletcher, Sally C, Hall, Charlotte, Kennedy, Tristan J, Pajusalu, Sander, Wojcik, Monica H, Boora, Uncaar, Li, Chan, Oja, Kaisa Teele, Hendrix, Eline, Westrip, Christian Ae, Andrijes, Regina, Piasecka, Sonia K, Singh, Mansi, El-Asrag, Mohammed E, Ptasinska, Anetta, Tillmann, Vallo, Higgs, Martin R, Carere, Deanna A, Beggs, Andrew D, Pappas, John, Rabin, Rachel, Smerdon, Stephen J, Stewart, Grant S, Õunap, Katrin, Coleman, Mathew L
Published in The Journal of clinical investigation (01.04.2023)
Published in The Journal of clinical investigation (01.04.2023)
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Journal Article
Asparaginyl Hydroxylation of the Notch Ankyrin Repeat Domain by Factor Inhibiting Hypoxia-inducible Factor
Coleman, Mathew L., McDonough, Michael A., Hewitson, Kirsty S., Coles, Charlotte, Mecinovicí, Jasmin, Edelmann, Mariola, Cook, Kristina M., Cockman, Matthew E., Lancaster, David E., Kessler, Benedikt M., Oldham, Neil J., Ratcliffe, Peter J., Schofield, Christopher J.
Published in The Journal of biological chemistry (17.08.2007)
Published in The Journal of biological chemistry (17.08.2007)
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Journal Article
Posttranslational Hydroxylation of Ankyrin Repeats in IκB Proteins by the Hypoxia-Inducible Factor (HIF) Asparaginyl Hydroxylase, Factor Inhibiting HIF (FIH)
Cockman, Matthew E., Lancaster, David E., Stolze, Ineke P., Hewitson, Kirsty S., McDonough, Michael A., Coleman, Mathew L., Coles, Charlotte H., Yu, Xiaohong, Hay, Ronald T., Ley, Steven C., Pugh, Christopher W., Oldham, Neil J., Masson, Norma, Schofield, Christopher J., Ratcliffe, Peter J.
Published in Proceedings of the National Academy of Sciences - PNAS (03.10.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (03.10.2006)
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Journal Article
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
Yang, Ming, Ge, Wei, Chowdhury, Rasheduzzaman, Claridge, Timothy D.W., Kramer, Holger B., Schmierer, Bernhard, McDonough, Michael A., Gong, Lingzhi, Kessler, Benedikt M., Ratcliffe, Peter J., Coleman, Mathew L., Schofield, Christopher J.
Published in The Journal of biological chemistry (04.03.2011)
Published in The Journal of biological chemistry (04.03.2011)
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Journal Article
Tumour hypoxia causes DNA hypermethylation by reducing TET activity
Thienpont, Bernard, Steinbacher, Jessica, Zhao, Hui, D’Anna, Flora, Kuchnio, Anna, Ploumakis, Athanasios, Ghesquière, Bart, Van Dyck, Laurien, Boeckx, Bram, Schoonjans, Luc, Hermans, Els, Amant, Frederic, Kristensen, Vessela N., Koh, Kian Peng, Mazzone, Massimiliano, Coleman, Mathew L., Carell, Thomas, Carmeliet, Peter, Lambrechts, Diether
Published in Nature (London) (01.09.2016)
Published in Nature (London) (01.09.2016)
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Journal Article
MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH)
Webb, James D, Murányi, Andrea, Pugh, Christopher W, Ratcliffe, Peter J, Coleman, Mathew L
Published in Biochemical journal (01.06.2009)
Published in Biochemical journal (01.06.2009)
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Journal Article
Rewiring protein binding specificity in paralogous DRG/DFRP complexes
Westrip, Christian A.E., Smerdon, Stephen J., Coleman, Mathew L.
Published in Structure (London) (07.11.2024)
Published in Structure (London) (07.11.2024)
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