An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
Zhang, Xuewu, Gureasko, Jodi, Shen, Kui, Cole, Philip A., Kuriyan, John
Published in Cell (16.06.2006)
Published in Cell (16.06.2006)
Get full text
Journal Article
Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
Min, Sang-Won, Cho, Seo-Hyun, Zhou, Yungui, Schroeder, Sebastian, Haroutunian, Vahram, Seeley, William W., Huang, Eric J., Shen, Yong, Masliah, Eliezer, Mukherjee, Chandrani, Meyers, David, Cole, Philip A., Ott, Melanie, Gan, Li
Published in Neuron (Cambridge, Mass.) (23.09.2010)
Published in Neuron (Cambridge, Mass.) (23.09.2010)
Get full text
Journal Article
Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution
Mo, Gary C H, Ross, Brian, Hertel, Fabian, Manna, Premashis, Yang, Xinxing, Greenwald, Eric, Booth, Chris, Plummer, Ashlee M, Tenner, Brian, Chen, Zan, Wang, Yuxiao, Kennedy, Eileen J, Cole, Philip A, Fleming, Karen G, Palmer, Amy, Jimenez, Ralph, Xiao, Jie, Dedecker, Peter, Zhang, Jin
Published in Nature methods (01.04.2017)
Published in Nature methods (01.04.2017)
Get full text
Journal Article
Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis
Chu, Nam, Salguero, Antonieta L., Liu, Albert Z., Chen, Zan, Dempsey, Daniel R., Ficarro, Scott B., Alexander, William M., Marto, Jarrod A., Li, Yana, Amzel, L. Mario, Gabelli, Sandra B., Cole, Philip A.
Published in Cell (09.08.2018)
Published in Cell (09.08.2018)
Get full text
Journal Article
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors
Kalin, Jay H, Wu, Muzhou, Gomez, Andrea V, Song, Yun, Das, Jayanta, Hayward, Dawn, Adejola, Nkosi, Wu, Mingxuan, Panova, Izabela, Chung, Hye Jin, Kim, Edward, Roberts, Holly J, Roberts, Justin M, Prusevich, Polina, Jeliazkov, Jeliazko R, Roy Burman, Shourya S, Fairall, Louise, Milano, Charles, Eroglu, Abdulkerim, Proby, Charlotte M, Dinkova-Kostova, Albena T, Hancock, Wayne W, Gray, Jeffrey J, Bradner, James E, Valente, Sergio, Mai, Antonello, Anders, Nicole M, Rudek, Michelle A, Hu, Yong, Ryu, Byungwoo, Schwabe, John W R, Mattevi, Andrea, Alani, Rhoda M, Cole, Philip A
Published in Nature communications (04.01.2018)
Published in Nature communications (04.01.2018)
Get full text
Journal Article
Acetylation of RNA Polymerase II Regulates Growth-Factor-Induced Gene Transcription in Mammalian Cells
Schröder, Sebastian, Herker, Eva, Itzen, Friederike, He, Daniel, Thomas, Sean, Gilchrist, Daniel A, Kaehlcke, Katrin, Cho, Sungyoo, Pollard, Katherine S, Capra, John A, Schnölzer, Martina, Cole, Philip A, Geyer, Matthias, Bruneau, Benoit G, Adelman, Karen, Ott, Melanie
Published in Molecular cell (07.11.2013)
Published in Molecular cell (07.11.2013)
Get full text
Journal Article
CBP Regulates Recruitment and Release of Promoter-Proximal RNA Polymerase II
Boija, Ann, Mahat, Dig Bijay, Zare, Aman, Holmqvist, Per-Henrik, Philip, Philge, Meyers, David J., Cole, Philip A., Lis, John T., Stenberg, Per, Mannervik, Mattias
Published in Molecular cell (02.11.2017)
Published in Molecular cell (02.11.2017)
Get full text
Journal Article
Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface
Pickin, Kerry A, Jura, Natalia, Cole, Philip A, Bose, Ron, Kuriyan, John, Zhang, Xuewu
Published in Nature (29.11.2007)
Published in Nature (29.11.2007)
Get full text
Journal Article
Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1
Shi, Yujiang, Lan, Fei, Matson, Caitlin, Mulligan, Peter, Whetstine, Johnathan R., Cole, Philip A., Casero, Robert A., Shi, Yang
Published in Cell (29.12.2004)
Published in Cell (29.12.2004)
Get full text
Journal Article
Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex
Song, Yun, Dagil, Lisbeth, Fairall, Louise, Robertson, Naomi, Wu, Mingxuan, Ragan, T.J., Savva, Christos G., Saleh, Almutasem, Morone, Nobuhiro, Kunze, Micha B.A., Jamieson, Andrew G., Cole, Philip A., Hansen, D. Flemming, Schwabe, John W.R.
Published in Cell reports (Cambridge) (25.02.2020)
Published in Cell reports (Cambridge) (25.02.2020)
Get full text
Journal Article
Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity
Cao, Jia, Peng, Jinghua, An, Hongying, He, Qiyi, Boronina, Tatiana, Guo, Shaodong, White, Morris F, Cole, Philip A, He, Ling
Published in Nature communications (25.07.2017)
Published in Nature communications (25.07.2017)
Get full text
Journal Article
The structural determinants of PH domain-mediated regulation of Akt revealed by segmental labeling
Chu, Nam, Viennet, Thibault, Bae, Hwan, Salguero, Antonieta, Boeszoermenyi, Andras, Arthanari, Haribabu, Cole, Philip A
Published in eLife (03.08.2020)
Published in eLife (03.08.2020)
Get full text
Journal Article
Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency‐Associated Genes
Mali, Prashant, Chou, Bin‐Kuan, Yen, Jonathan, Ye, Zhaohui, Zou, Jizhong, Dowey, Sarah, Brodsky, Robert A., Ohm, Joyce E., Yu, Wayne, Baylin, Stephen B., Yusa, Kosuke, Bradley, Allan, Meyers, David J., Mukherjee, Chandrani, Cole, Philip A., Cheng, Linzhao
Published in Stem cells (Dayton, Ohio) (01.04.2010)
Published in Stem cells (Dayton, Ohio) (01.04.2010)
Get full text
Journal Article
Combined targeting of the BRD4-NUT-p300 axis in NUT midline carcinoma by dual selective bromodomain inhibitor, NEO2734
Morrison-Smith, Chevaun D, Knox, Tatiana M, Filic, Ivona, Soroko, Kara M, Eschle, Benjamin K, Wilkens, Margaret K, Gokhale, Prafulla C, Giles, Francis, Griffin, Andrew, Brown, Bill, Shapiro, Geoffrey I, Zucconi, Beth E, Cole, Philip A, Lemieux, Madeleine E, French, Christopher A
Published in Molecular cancer therapeutics (01.07.2020)
Published in Molecular cancer therapeutics (01.07.2020)
Get full text
Journal Article
The structural basis of protein acetylation by the p300/CBP transcriptional coactivator
Marmorstein, Ronen, Thompson, Paul R, Cole, Philip A, Wang, Ling, Hwang, Yousang, Zhao, Kehao, Liu, Xin
Published in Nature (14.02.2008)
Published in Nature (14.02.2008)
Get full text
Journal Article
The structural basis of PTEN regulation by multi-site phosphorylation
Dempsey, Daniel R, Viennet, Thibault, Iwase, Reina, Park, Eunyoung, Henriquez, Stephanie, Chen, Zan, Jeliazkov, Jeliazko R, Palanski, Brad A, Phan, Kim L, Coote, Paul, Gray, Jeffrey J, Eck, Michael J, Gabelli, Sandra B, Arthanari, Haribabu, Cole, Philip A
Published in Nature structural & molecular biology (01.10.2021)
Published in Nature structural & molecular biology (01.10.2021)
Get full text
Journal Article