Discovery of Novel Indoline Cholesterol Ester Transfer Protein Inhibitors (CETP) through a Structure-Guided Approach
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Published in ACS medicinal chemistry letters (10.03.2016)
Published in ACS medicinal chemistry letters (10.03.2016)
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Synthesis and evaluation of N-[(1 S,2 S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists
Du, Wu, Jewell, James P., Lin, Linus S., Colandrea, Vincent J., Xiao, Jing C., Lao, Julie, Shen, Chun-Pyn, Bateman, Thomas J., Reddy, Vijay B.G., Ha, Sookhee N., Shah, Shrenik K., Fong, Tung M., Hale, Jeffrey J., Hagmann, William K.
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
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1,3,8-Triazaspiro[4.5]decane-2,4-diones as Efficacious Pan-Inhibitors of Hypoxia-Inducible Factor Prolyl Hydroxylase 1–3 (HIF PHD1–3) for the Treatment of Anemia
Vachal, Petr, Miao, Shouwu, Pierce, Joan M, Guiadeen, Deodial, Colandrea, Vincent J, Wyvratt, Matthew J, Salowe, Scott P, Sonatore, Lisa M, Milligan, James A, Hajdu, Richard, Gollapudi, Anantha, Keohane, Carol A, Lingham, Russell B, Mandala, Suzanne M, DeMartino, Julie A, Tong, Xinchun, Wolff, Michael, Steinhuebel, Dietrich, Kieczykowski, Gerard R, Fleitz, Fred J, Chapman, Kevin, Athanasopoulos, John, Adam, Gregory, Akyuz, Can D, Jena, Dhirendra K, Lusen, Jeffrey W, Meng, Juncai, Stein, Benjamin D, Xia, Lei, Sherer, Edward C, Hale, Jeffrey J
Published in Journal of medicinal chemistry (12.04.2012)
Published in Journal of medicinal chemistry (12.04.2012)
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Discovery of Orally Bioavailable and Liver-Targeted Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PHD) Inhibitors for the Treatment of Anemia
Liu, Ping, Wang, Liping, DuBois, Byron G, Colandrea, Vincent J, Liu, Rongqiang, Cai, Jiaqiang, Du, Xiaoxing, Quan, Weiguo, Morris, William, Bai, Jianwu, Bishwokarma, Bimjhana, Cheng, Mangeng, Piesvaux, Jennifer, Ray, Kallol, Alpert, Carla, Chiu, Chi-Sung, Zielstorff, Mark, Metzger, Joseph M, Yang, Liming, Leung, Dennis, Alleyne, Candice, Vincent, Stella H, Pucci, Vincenzo, Li, Xiaofang, Crespo, Alejandro, Stickens, Dominique, Hale, Jeffrey J, Ujjainwalla, Feroze, Sinz, Christopher J
Published in ACS medicinal chemistry letters (13.12.2018)
Published in ACS medicinal chemistry letters (13.12.2018)
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Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor
Neelamkavil, Santhosh F, Agrawal, Sony, Bara, Thomas, Bennett, Chad, Bhat, Sathesh, Biswas, Dipshikha, Brockunier, Linda, Buist, Nicole, Burnette, Duane, Cartwright, Mark, Chackalamannil, Samuel, Chase, Robert, Chelliah, Mariappan, Chen, Austin, Clasby, Martin, Colandrea, Vincent J, Davies, Ian W, Eagen, Keith, Guo, Zhuyan, Han, Yongxin, Howe, John, Jayne, Charles, Josien, Hubert, Kargman, Stacia, Marcantonio, Karen, Miao, Shouwu, Miller, Randy, Nolting, Andrew, Pinto, Patrick, Rajagopalan, Murali, Ruck, Rebecca T, Shah, Unmesh, Soriano, Aileen, Sperbeck, Donald, Velazquez, Francisco, Wu, Jin, Xia, Yan, Venkatraman, Srikanth
Published in ACS medicinal chemistry letters (14.01.2016)
Published in ACS medicinal chemistry letters (14.01.2016)
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Synthesis of the Mitomycin and FR900482 Ring Systems via Dimethyldioxirane Oxidation
Colandrea, Vincent J, Rajaraman, Shanthi, Jimenez, Leslie S
Published in Organic letters (20.03.2003)
Published in Organic letters (20.03.2003)
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Substituted acyclic sulfonamides as human cannabinoid-1 receptor inverse agonists
Armstrong, Helen E., Galka, Amy, Lin, Linus S., Lanza, Thomas J., Jewell, James P., Shah, Shrenik K., Guthikonda, Ravi, Truong, Quang, Chang, Linda L., Quaker, Grace, Colandrea, Vincent J., Tong, Xinchun, Wang, Junying, Xu, Sherry, Fong, Tung M., Shen, Chun-Pyn, Lao, Julie, Chen, Jing, Shearman, Lauren P., Stribling, D. Sloan, Rosko, Kimberly, Strack, Alison, Ha, Sookhee, der Ploeg, Lex Van, Goulet, Mark T., Hagmann, William K.
Published in Bioorganic & medicinal chemistry letters (15.04.2007)
Published in Bioorganic & medicinal chemistry letters (15.04.2007)
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요로 감염의 치료에 유용한 C-만노시드 화합물
WIDDOWSON KATHERINE LOUISA, STEWART EUGENE L, MCGRANE LAUREL KATHRYN, BISHOP MICHAEL JOSEPH, LI YUEHU, STRAMBEANU IULIA, COLANDREA VINCENT J, JANETKA JAMES WALTER
Year of Publication 22.03.2021
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Year of Publication 22.03.2021
Patent
2,5-Disubstituted pyrrolidine carboxylates as potent, orally active sphingosine-1-phosphate (S1P) receptor agonists
Colandrea, Vincent J., Legiec, Irene E., Huo, Pei, Yan, Lin, Hale, Jeffrey J., Mills, Sander G., Bergstrom, James, Card, Deborah, Chebret, Gary, Hajdu, Richard, Keohane, Carol Ann, Milligan, James A., Rosenbach, Mark J., Shei, Gan-Ju, Mandala, Suzanne M.
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
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The pharmacokinetics of a thiazole benzenesulfonamide β3-adrenergic receptor agonist and its analogs in rats, dogs, and monkeys: Improving oral bioavailability
STEARNS, Ralph A, MILLER, Randy R, COLLETTI, Adria E, STRAUSS, John R, KEOHANE, Carol Ann, FEENEY, William P, ILIFF, Susan A, CHIU, Shuet-Hing Lee, WEI TANG, KWEI, Gloria Y, TANG, Frank S, MATHVINK, Robert J, NAYLOR, Elizabeth M, CHITTY, Dawn, COLANDREA, Vincent J, WEBER, Ann E
Published in Drug metabolism and disposition (2002)
Published in Drug metabolism and disposition (2002)
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Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective β3 adrenergic receptor agonist antiobesity agents
BIFTU, T, FENG, D. D, FORREST, M. J, HOM, G. J, MACLNTYRE, D. E, STEARNS, R. A, STRADER, C. D, WYVRATT, M. J, FISHER, M. H, WEBER, A. E, LIANG, G.-B, KUO, H, XIAOXIA QIAN, NAYLOR, E. M, COLANDREA, V. J, CANDELORE, M. R, CASCIERI, M. A, COLWELL, L. F
Published in Bioorganic & medicinal chemistry letters (03.07.2000)
Published in Bioorganic & medicinal chemistry letters (03.07.2000)
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The pharmacokinetics of a thiazole benzenesulfonamide beta 3-adrenergic receptor agonist and its analogs in rats, dogs, and monkeys: improving oral bioavailability
Stearns, Ralph A, Miller, Randy R, Tang, Wei, Kwei, Gloria Y, Tang, Frank S, Mathvink, Robert J, Naylor, Elizabeth M, Chitty, Dawn, Colandrea, Vincent J, Weber, Ann E, Colletti, Adria E, Strauss, John R, Keohane, Carol Ann, Feeney, William P, Iliff, Susan A, Chiu, Shuet-Hing Lee
Published in Drug metabolism and disposition (01.07.2002)
Published in Drug metabolism and disposition (01.07.2002)
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NOVEL CYCLIC AZABENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS
LI BING, APGAR JAMES M, WILKENING ROBERT R, LEAVITT KENNETH J, CHU LIN, FENG DANQING, ANAND RAJAN, JIANG JINLONG, CHEN PING, QIAN XIAOXIA, DROPINSKI JAMES F, BIFTU TESFAYE, KIM ALEXANDER J, SEBHAT IYASSU, HICKS JACQUELINE D, WEI LAN, COLANDREA VINCENT J, DONG GUIZHEN, WU ZHICAI
Year of Publication 02.07.2015
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Year of Publication 02.07.2015
Patent
NOVEL CYCLIC AZABENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS
LI BING, APGAR JAMES M, WILKENING ROBERT R, LEAVITT KENNETH J, CHU LIN, FENG DANQING, ANAND RAJAN, JIANG JINLONG, CHEN PING, QIAN XIAOXIA, DROPINSKI JAMES F, BIFTU TESFAYE, KIM ALEXANDER J, SEBHAT IYASSU, HICKS JACQUELINE D, WEI LAN, COLANDREA VINCENT J, DONG GUIZHEN, WU ZHICAI
Year of Publication 26.11.2013
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Year of Publication 26.11.2013
Patent
Synthesis and evaluation of N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyll-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists
WU DU, JEWELL, James P, SHAH, Shrenik K, FONG, Tung M, HALE, Jeffrey J, HAGMANN, William K, LIN, Linus S, COLANDREA, Vincent J, XIAO, Jing C, JULIE LAO, SHEN, Chun-Pyn, BATEMAN, Thomas J, REDDY, Vijay B. G, HA, Sookhee N
Published in Bioorganic & medicinal chemistry letters (2009)
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Published in Bioorganic & medicinal chemistry letters (2009)
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Improved synthesis of aryl 1,1-dimethylpropargyl ethers
Godfrey, Jollie D., Mueller, Richard H., Sedergran, Thomas C., Soundararajan, Nachimuthu, Colandrea, Vincent J.
Published in Tetrahedron letters (29.08.1994)
Published in Tetrahedron letters (29.08.1994)
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