LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response
Serganova, Inna, Cohen, Ivan J, Vemuri, Kiranmayi, Shindo, Masahiro, Maeda, Masatomo, Mane, Mayuresh, Moroz, Ekaterina, Khanin, Raya, Satagopan, Jaya, Koutcher, Jason A, Blasberg, Ronald
Published in PloS one (24.09.2018)
Published in PloS one (24.09.2018)
Get full text
Journal Article
Impact of the Tumor Microenvironment on Tumor-Infiltrating Lymphocytes: Focus on Breast Cancer
Get full text
Journal Article
Book Review
Increased tumor glycolysis is associated with decreased immune infiltration across human solid tumors
Cohen, Ivan J, Pareja, Fresia, Socci, Nicholas D, Shen, Ronglai, Doane, Ashley S, Schwartz, Jazmin, Khanin, Raya, Morris, Elizabeth A, Sutton, Elizabeth J, Blasberg, Ronald G
Published in Frontiers in immunology (24.11.2022)
Published in Frontiers in immunology (24.11.2022)
Get full text
Journal Article
LDH-A-Modulation and the Variability of LDH Isoenzyme Profiles in Murine Gliomas: A Link with Metabolic and Growth Responses
Shindo, Masahiro, Maeda, Masatomo, Myat, Ko, Mane, Mayuresh M, Cohen, Ivan J, Vemuri, Kiranmayi, Albeg, Avi S, Serganova, Inna, Blasberg, Ronald
Published in Cancers (06.05.2022)
Published in Cancers (06.05.2022)
Get full text
Journal Article
Genetic and Drug Inhibition of LDH-A: Effects on Murine Gliomas
Maeda, Masatomo, Ko, Myat, Mane, Mayuresh M, Cohen, Ivan J, Shindo, Masahiro, Vemuri, Kiranmayi, Serganova, Inna, Blasberg, Ronald
Published in Cancers (06.05.2022)
Published in Cancers (06.05.2022)
Get full text
Journal Article
Lactate Dehydrogenase A Depletion Alters MyC-CaP Tumor Metabolism, Microenvironment, and CAR T Cell Therapy
Mane, Mayuresh M., Cohen, Ivan J., Ackerstaff, Ellen, Shalaby, Khalid, Ijoma, Jenny N., Ko, Myat, Maeda, Masatomo, Albeg, Avi S., Vemuri, Kiranmayi, Satagopan, Jaya, Moroz, Anna, Zurita, Juan, Shenker, Larissa, Shindo, Masahiro, Nickles, Tanner, Nikolov, Ekaterina, Moroz, Maxim A., Koutcher, Jason A., Serganova, Inna, Ponomarev, Vladimir, Blasberg, Ronald G.
Published in Molecular therapy. Oncolytics (25.09.2020)
Published in Molecular therapy. Oncolytics (25.09.2020)
Get full text
Journal Article
CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours
Zappasodi, Roberta, Serganova, Inna, Cohen, Ivan J., Maeda, Masatomo, Shindo, Masahiro, Senbabaoglu, Yasin, Watson, McLane J., Leftin, Avigdor, Maniyar, Rachana, Verma, Svena, Lubin, Matthew, Ko, Myat, Mane, Mayuresh M., Zhong, Hong, Liu, Cailian, Ghosh, Arnab, Abu-Akeel, Mohsen, Ackerstaff, Ellen, Koutcher, Jason A., Ho, Ping-Chih, Delgoffe, Greg M., Blasberg, Ronald, Wolchok, Jedd D., Merghoub, Taha
Published in Nature (London) (25.03.2021)
Published in Nature (London) (25.03.2021)
Get full text
Journal Article
CTLA-4 blockade drives loss of T reg stability in glycolysis-low tumours
Zappasodi, Roberta, Serganova, Inna, Cohen, Ivan J, Maeda, Masatomo, Shindo, Masahiro, Senbabaoglu, Yasin, Watson, McLane J, Leftin, Avigdor, Maniyar, Rachana, Verma, Svena, Lubin, Matthew, Ko, Myat, Mane, Mayuresh M, Zhong, Hong, Liu, Cailian, Ghosh, Arnab, Abu-Akeel, Mohsen, Ackerstaff, Ellen, Koutcher, Jason A, Ho, Ping-Chih, Delgoffe, Greg M, Blasberg, Ronald, Wolchok, Jedd D, Merghoub, Taha
Published in Nature (London) (25.03.2021)
Published in Nature (London) (25.03.2021)
Get full text
Journal Article
Gold/alpha-lactalbumin nanoprobes for the imaging and treatment of breast cancer
Yang, Jiang, Wang, Tai, Zhao, Lina, Rajasekhar, Vinagolu K, Joshi, Suhasini, Andreou, Chrysafis, Pal, Suchetan, Hsu, Hsiao-Ting, Zhang, Hanwen, Cohen, Ivan J, Huang, Ruimin, Hendrickson, Ronald C, Miele, Matthew M, Pei, Wenbo, Brendel, Matthew B, Healey, John H, Chiosis, Gabriela, Kircher, Moritz F
Published in Nature biomedical engineering (01.07.2020)
Published in Nature biomedical engineering (01.07.2020)
Get full text
Journal Article
Bendamustine lymphodepletion before axicabtagene ciloleucel is safe and associates with reduced inflammatory cytokines
Ghilardi, Guido, Paruzzo, Luca, Svoboda, Jakub, Chong, Elise A., Shestov, Alexander A., Chen, Linhui, Cohen, Ivan J., Gabrielli, Giulia, Nasta, Sunita D., Porazzi, Patrizia, Landsburg, Daniel J., Gerson, James N., Carter, Jordan, Barta, Stefan K., Yelton, Rebecca, Pajarillo, Raymone, Patel, Vrutti, White, Griffin, Ballard, Hatcher J., Weber, Elizabeth, Napier, Ellen, Chong, Emeline R., Fraietta, Joseph A., Garfall, Alfred L., Porter, David L., Milone, Michael C., O’Connor, Roderick, Schuster, Stephen J., Ruella, Marco
Published in Blood advances (13.02.2024)
Published in Blood advances (13.02.2024)
Get full text
Journal Article
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC
Javitt, Aaron, Shmueli, Merav D, Kramer, Matthias P, Kolodziejczyk, Aleksandra A, Cohen, Ivan J, Radomir, Lihi, Sheban, Daoud, Kamer, Iris, Litchfield, Kevin, Bab-Dinitz, Elizabeta, Zadok, Oranit, Neiens, Vanessa, Ulman, Adi, Wolf-Levy, Hila, Eisenberg-Lerner, Avital, Kacen, Assaf, Alon, Michal, Rêgo, Ana Toste, Stacher-Priehse, Elvira, Lindner, Michael, Koch, Ina, Bar, Jair, Swanton, Charles, Samuels, Yardena, Levin, Yishai, da Fonseca, Paula C A, Elinav, Eran, Friedman, Nir, Meiners, Silke, Merbl, Yifat
Published in Nature cancer (01.05.2023)
Published in Nature cancer (01.05.2023)
Get more information
Journal Article
CTLA-4 blockade drives loss of T.sub.reg stability in glycolysis-low tumours
Zappasodi, Roberta, Serganova, Inna, Cohen, Ivan J, Maeda, Masatomo, Shindo, Masahiro, Senbabaoglu, Yasin, Watson, McLane J
Published in Nature (London) (25.03.2021)
Published in Nature (London) (25.03.2021)
Get full text
Journal Article
Inhibition of EZH2 Improves CART19 Immunotherapy By Reprogramming Lymphoma Tumor Cells and Enhancing T-Cell Functionality
Porazzi, Patrizia, Isshiki, Yusuke, Ghilardi, Guido, Nason, Siena, Yang, Ziqi, Carturan, Alberto, Chen, Linhui, Zhang, Yunlin, Patel, Ruchi P., Guruprasad, Puneeth, Ugwuanyi, Ositadimma, Cohen, Ivan J, Schuster, Stephen J, Melnick, Ari M, Béguelin, Wendy, Ruella, Marco
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
Get full text
Journal Article
Precision Targeting of the Malignant Clone in Diffuse Large B Cell Lymphoma Using Chimeric Antigen Receptor T Cells Against the Clonotypic IGHV4-34 B Cell Receptor
Cohen, Ivan J, Bochi-Layec, Audrey C, Kim, Ki Hyun, Jenks, Scott, Ugwuanyi, Ositadimma, Ghilardi, Guido, Gabrielli, Giulia, Harris, Jaryse, Wang, Li-Ping, Zhang, Yunlin, Pajarillo, Raymone, Vlachonikola, Elisavet, Porazzi, Patrizia, Sanz, Ignacio, Ghia, Paolo, Stamatopoulos, Kostas, Schuster, Stephen J, Ruella, Marco
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
Get full text
Journal Article
Modulation of the Btla-HVEM Axis to Enhance CAR T Cell Immunotherapy Against Cancer
Guruprasad, Puneeth, Carturan, Alberto, Zhang, Yunlin, Kumashie, Kingsley Gideon, Cohen, Ivan J, Ghilardi, Guido, Kim, Ki-Hyun, Lee, Jong-Seo, Lee, Yoon, Kim, Jong-Hoon, Chung, Junho, Shestov, Maksim, Pajarillo, Raymone, Harris, Jaryse, Lee, Yong Gu, Wang, Michael, Ballard, Hatcher, Gupta, Aasha, Ugwuanyi, Ositadimma, Hong, Seok Jae, Chen, Linhui, Paruzzo, Luca, Kammerman, Shane, Patel, Ruchi P., Shestova, Olga, Vella, Laura, Schuster, Stephen J., Svoboda, Jakub, Porazzi, Patrizia, Ruella, Marco
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
Get full text
Journal Article
Bendamustine Is Less Toxic Than Fludarabine-Cyclophosphamide-Based Lymphodepletion before CD28-Costimulated CART19 through Reduced Inflammatory Cytokines
Ghilardi, Guido, Paruzzo, Luca, Svoboda, Jakub, Chong, Elise A., Shestov, Alexander, Chen, Linhui, Cohen, Ivan J, Gabrielli, Giulia, Nasta, Dwivedy S., Porazzi, Patrizia, Landsburg, Daniel J., Gerson, James, Carter, Jordan, Barta, Stefan K., Yelton, Rebecca, Pajarillo, Raymone, White, Griffin W, Ballard, Hatcher, Weber, Elizabeth, Napier, Ellen B., Chong, Emeline R., Fraietta, Joseph A, Garfall, Alfred L., Porter, David L., Milone, Michael C., O'Connor, Roderick, Schuster, Stephen J., Ruella, Marco
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
Get full text
Journal Article
A First-in-Human Phase I Study of AT101, a Novel Anti-CD19 Chimeric Antigen Receptor T Cell Product Targeting a Membrane-Proximal Domain of CD19 in Adults with Relapsed or Refractory B Cell Non-Hodgkin Lymphoma
Zhang, Yunlin, Patel, Ruchi P., Kim, Ki Hyun, Cho, Hyungwoo, Cho, Jae-Cheol, Jeong, Seong Hyun, Oh, Sung Yong, Choi, Yoon Seok, Kim, Sung-Hyun, Lee, Ji Hyun, Angelos, Mathew G., Guruprasad, Puneeth, Cohen, Ivan J, Ugwuanyi, Ositadimma, Lee, Yong Gu, Pajarillo, Raymone, Cho, Jong Hyun, Carturan, Alberto, Paruzzo, Luca, Ghilardi, Guido, Kim, Soohwan, Kim, Sung Min, Lee, Hyun Jong, Park, Ji Ho, Cui, Lei Guang, Lee, Tae Bum, Hwang, Insik, Lee, Youngha, Lee, Yong-Jun, Porazzi, Patrizia, Liu, Dongfang, Lee, Yoon, Kim, Jong Hoon, Lee, Jong Seo, Yoon, Dok Hyun, Chung, Junho, Ruella, Marco
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
Get full text
Journal Article