Mechanistic Studies of a Palladium-Catalyzed Intramolecular Hydroamination of Unactivated Alkenes: Protonolysis of a Stable Palladium Alkyl Complex Is the Turnover-Limiting Step
Cochran, Brian M, Michael, Forrest E
Published in Journal of the American Chemical Society (05.03.2008)
Published in Journal of the American Chemical Society (05.03.2008)
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Journal Article
Room Temperature Palladium-Catalyzed Intramolecular Hydroamination of Unactivated Alkenes
Michael, Forrest E, Cochran, Brian M
Published in Journal of the American Chemical Society (05.04.2006)
Published in Journal of the American Chemical Society (05.04.2006)
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Journal Article
Development of a Commercial Process To Prepare AMG 232 Using a Green Ozonolysis–Pinnick Tandem Transformation
Cochran, Brian M, Corbett, Michael T, Correll, Tiffany L, Fang, Yuan-Qing, Flick, Tawnya G, Jones, Siân C, Silva Elipe, Maria V, Smith, Austin G, Tucker, John L, Vounatsos, Filisaty, Wells, Greg, Yeung, David, Walker, Shawn D, Bio, Matthew M, Caille, Seb
Published in Journal of organic chemistry (19.04.2019)
Published in Journal of organic chemistry (19.04.2019)
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Journal Article
Design and synthesis of benzoazepinone-derived cyclic malonamides and aminoamides as potent γ-secretase inhibitors
Yang, Michael G., Shi, Jian-Liang, Modi, Dilip P., Wells, Jennifer, Cochran, Brian M., Wolf, Mark A., Thompson, Lorin A., Ramanjulu, Mercy M., Roach, Arthur H., Zaczek, Robert, Robertson, David W., Wexler, Ruth R., Olson, Richard E.
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
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Journal Article
Discovery of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid diamides that increase CFTR mediated chloride transport
Hirth, Bradford H., Qiao, Shuang, Cuff, Lisa M., Cochran, Brian M., Pregel, Marko J., Gregory, Jill S., Sneddon, Scott F., Kane, John L.
Published in Bioorganic & medicinal chemistry letters (15.04.2005)
Published in Bioorganic & medicinal chemistry letters (15.04.2005)
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Journal Article
Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor
Zhang, Liang, Griffin, Daniel J., Beaver, Matthew G., Blue, Laura E., Borths, Christopher J., Brown, Derek B., Caille, Seb, Chen, Ying, Cherney, Alan H., Cochran, Brian M., Colyer, John T., Corbett, Michael T., Correll, Tiffany L., Crockett, Richard D., Dai, Xi-Jie, Dornan, Peter K., Farrell, Robert P., Hedley, Simon J., Hsieh, Hsiao-Wu, Huang, Liang, Huggins, Seth, Liu, Min, Lovette, Michael A., Quasdorf, Kyle, Reifman, Jonathan, Robinson, Jo Anna, Sangodkar, Rahul P., Sharma, Sonika, Kumar, Srividya Sharvan, Smith, Austin G., St-Pierre, Gabrielle, Tedrow, Jason S., Thiel, Oliver R., Truong, Jonathan V., Walker, Shawn D., Wei, Carolyn S., Wilsily, Ashraf, Xie, Yong, Yang, Ning, Parsons, Andrew T.
Published in Organic process research & development (18.11.2022)
Published in Organic process research & development (18.11.2022)
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Journal Article
The Catalytic Alkylative Desymmetrization of Anhydrides in a Formal Synthesis of Ionomycin
Oberg, Kevin M., Cochran, Brian M., Cook, Matthew J., Rovis, Tomislav
Published in Synthesis (Stuttgart) (01.11.2018)
Published in Synthesis (Stuttgart) (01.11.2018)
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Journal Article
Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRAS G12C Inhibitor
Zhang, Liang, Griffin, Daniel J., Beaver, Matthew G., Blue, Laura E., Borths, Christopher J., Brown, Derek B., Caille, Seb, Chen, Ying, Cherney, Alan H., Cochran, Brian M., Colyer, John T., Corbett, Michael T., Correll, Tiffany L., Crockett, Richard D., Dai, Xi-Jie, Dornan, Peter K., Farrell, Robert P., Hedley, Simon J., Hsieh, Hsiao-Wu, Huang, Liang, Huggins, Seth, Liu, Min, Lovette, Michael A., Quasdorf, Kyle, Powazinik, William, Reifman, Jonathan, Robinson, Jo Anna, Sangodkar, Rahul P., Sharma, Sonika, Kumar, Srividya Sharvan, Smith, Austin G., St-Pierre, Gabrielle, Tedrow, Jason S., Thiel, Oliver R., Truong, Jonathan V., Walker, Shawn D., Wei, Carolyn S., Wilsily, Ashraf, Xie, Yong, Yang, Ning, Parsons, Andrew T.
Published in Organic process research & development (18.11.2022)
Published in Organic process research & development (18.11.2022)
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Journal Article
MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE
COSTA, Christina Marie, COCHRAN, Brian M, PAGANO, Nicholas, STIRN, Scott, HARRIOTT, Nicole
Year of Publication 15.05.2024
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Year of Publication 15.05.2024
Patent
MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE
COSTA, Christina Marie, COCHRAN, Brian M, PAGANO, Nicholas, STIRN, Scott, HARRIOTT, Nicole
Year of Publication 15.05.2024
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Year of Publication 15.05.2024
Patent