A Physiologically-Based Pharmacokinetic Model to Describe Ciprofloxacin Pharmacokinetics Over the Entire Span of Life
Schlender, Jan-Frederik, Teutonico, Donato, Coboeken, Katrin, Schnizler, Katrin, Eissing, Thomas, Willmann, Stefan, Jaehde, Ulrich, Stass, Heino
Published in Clinical pharmacokinetics (01.12.2018)
Published in Clinical pharmacokinetics (01.12.2018)
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Development of a Physiologically-Based Pharmacokinetic Model for Preterm Neonates: Evaluation with In Vivo Data
Claassen, Karina, Thelen, Kirstin, Coboeken, Katrin, Gaub, Thomas, Lippert, Jorg, Allegaert, Karel, Willmann, Stefan
Published in Current pharmaceutical design (01.01.2015)
Published in Current pharmaceutical design (01.01.2015)
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Journal Article
Pharmacokinetics of rivaroxaban in children using physiologically based and population pharmacokinetic modelling: an EINSTEIN-Jr phase I study
Willmann, Stefan, Thelen, Kirstin, Kubitza, Dagmar, Lensing, Anthonie W A, Frede, Matthias, Coboeken, Katrin, Stampfuss, Jan, Burghaus, Rolf, Mück, Wolfgang, Lippert, Jörg
Published in Thrombosis journal (04.12.2018)
Published in Thrombosis journal (04.12.2018)
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Journal Article
Evaluation of changes in oral drug absorption in preterm and term neonates for Biopharmaceutics Classification System (BCS) class I and II compounds
Somani, Amit A., Thelen, Kirstin, Zheng, Songmao, Trame, Mirjam N., Coboeken, Katrin, Meyer, Michaela, Schnizler, Katrin, Ince, Ibrahim, Willmann, Stefan, Schmidt, Stephan
Published in British journal of clinical pharmacology (01.01.2016)
Published in British journal of clinical pharmacology (01.01.2016)
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Journal Article
Application of Physiologically‐Based and Population Pharmacokinetic Modeling for Dose Finding and Confirmation During the Pediatric Development of Moxifloxacin
Willmann, Stefan, Frei, Matthias, Sutter, Gabriele, Coboeken, Katrin, Wendl, Thomas, Eissing, Thomas, Lippert, Jörg, Stass, Heino
Published in CPT: pharmacometrics and systems pharmacology (01.09.2019)
Published in CPT: pharmacometrics and systems pharmacology (01.09.2019)
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Journal Article
Model‐informed bridging of rivaroxaban doses for thromboprophylaxis in pediatric patients aged 9 years and older with congenital heart disease
Willmann, Stefan, Ince, Ibrahim, Ahsman, Maurice, Coboeken, Katrin, Zhang, Yang, Thelen, Kirstin, Kubitza, Dagmar, Zannikos, Peter, Zhou, Wangda, Pina, Liza Miriam, Post, Teun, Lippert, Jörg
Published in CPT: pharmacometrics and systems pharmacology (01.08.2022)
Published in CPT: pharmacometrics and systems pharmacology (01.08.2022)
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Journal Article
Population pharmacokinetic analysis of rivaroxaban in children and comparison to prospective physiologically‐based pharmacokinetic predictions
Willmann, Stefan, Coboeken, Katrin, Zhang, Yang, Mayer, Hannah, Ince, Ibrahim, Mesic, Emir, Thelen, Kirstin, Kubitza, Dagmar, Lensing, Anthonie W. A., Yang, Haitao, Zhu, Peijuan, Mück, Wolfgang, Drenth, Henk‐Jan, Lippert, Jörg
Published in CPT: pharmacometrics and systems pharmacology (01.10.2021)
Published in CPT: pharmacometrics and systems pharmacology (01.10.2021)
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Journal Article
Evaluation of the efficacy and safety of rivaroxaban using a computer model for blood coagulation
Burghaus, Rolf, Coboeken, Katrin, Gaub, Thomas, Kuepfer, Lars, Sensse, Anke, Siegmund, Hans-Ulrich, Weiss, Wolfgang, Mueck, Wolfgang, Lippert, Joerg
Published in PloS one (22.04.2011)
Published in PloS one (22.04.2011)
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Journal Article
Baseline clusters and the response to positive airway pressure treatment in obstructive sleep apnoea patients: longitudinal data from the European Sleep Apnea Database cohort
Yassen, Ashraf, Coboeken, Katrin, Bailly, Sébastien, Burghaus, Rolf, Buskova, Jitka, Dogas, Zoran, Drummond, Marta, Gouveris, Haralampos, Joppa, Pavol, Lippert, Joerg, Lombardi, Carolina, Mihaicuta, Stefan, Pépin, Jean Louis, Zou, Ding, Hedner, Jan, Grote, Ludger, Steiropoulos, P., Verbraecken, J., Petiet, E., Trakada, G., Fietze, I., Penzel, T., Laharnar, N., Ludka, O., Bouloukaki, I., Schiza, S., McNicholas, W.T., Ryan, S., Riha, R.L., Kvamme, J.A., Grote, L., Hedner, J., Zou, D., Pevernagie, D., Bailly, S., Pépin, J.L., Tamisier, R., Hein, H., Basoglu, O.K., Tasbakan, M.S., Buskova, J., Joppa, P., Staats, R., Testelmans, D., Gouveris, H., Ludwig, K., Lombardi, C., Parati, G., Bonsignore, M.R., Fanfulla, F., Petitjean, M., Roisman, G., Drummond, M., van Zeller, M., Treml, M., Randerath, W., Dogas, Z., Pecotic, R., Pataka, A., Mihaicuta, S., Anttalainen, U., Saaresranta, T., Sliwinski, S.
Published in ERJ open research (01.10.2022)
Published in ERJ open research (01.10.2022)
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Journal Article
A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways
Dallmann, André, Ince, Ibrahim, Coboeken, Katrin, Eissing, Thomas, Hempel, Georg
Published in Clinical pharmacokinetics (01.06.2018)
Published in Clinical pharmacokinetics (01.06.2018)
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Journal Article
Applications of Physiologically Based Pharmacokinetic Modeling of Rivaroxaban—Renal and Hepatic Impairment and Drug‐Drug Interaction Potential
Willmann, Stefan, Coboeken, Katrin, Kapsa, Stefanie, Thelen, Kirstin, Mundhenke, Markus, Fischer, Kerstin, Hügl, Burkhard, Mück, Wolfgang
Published in Journal of clinical pharmacology (01.05.2021)
Published in Journal of clinical pharmacology (01.05.2021)
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Journal Article
Evolution of a detailed physiological model to simulate the gastrointestinal transit and absorption process in humans, Part 1: Oral solutions
Thelen, Kirstin, Coboeken, Katrin, Willmann, Stefan, Burghaus, Rolf, Dressman, Jennifer B., Lippert, Jörg
Published in Journal of pharmaceutical sciences (01.12.2011)
Published in Journal of pharmaceutical sciences (01.12.2011)
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Journal Article
Abstract 10922: Depression and Heart Rate Variability in Individuals with Heart Failure - Results from the Myovasc Study
Ghaemi Kerahrodi, Jasmin, Prochaska, Juergen, Buch, Gregor, Zeid, Silav, Coboeken, Katrin, Velmeden, David, Soehne, Jakob, Schuch, Alexander, Beutel, Manfred E., Muenzel, Thomas, Gori, Tomaso, Wild, Philipp, Michal, Matthias
Published in Circulation (New York, N.Y.) (16.11.2021)
Published in Circulation (New York, N.Y.) (16.11.2021)
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Journal Article
Development of a Paediatric Population-Based Model of the Pharmacokinetics of Rivaroxaban
Willmann, Stefan, Becker, Corina, Burghaus, Rolf, Coboeken, Katrin, Edginton, Andrea, Lippert, Jörg, Siegmund, Hans-Ulrich, Thelen, Kirstin, Mück, Wolfgang
Published in Clinical pharmacokinetics (01.01.2014)
Published in Clinical pharmacokinetics (01.01.2014)
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Predictive Performance of Physiology‐Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small‐Molecule Compounds in Children
Ince, Ibrahim, Dallmann, André, Frechen, Sebastian, Coboeken, Katrin, Niederalt, Christoph, Wendl, Thomas, Block, Michael, Meyer, Michaela, Eissing, Thomas, Burghaus, Rolf, Lippert, Jörg, Willmann, Stefan, Schlender, Jan‐Frederik
Published in Journal of clinical pharmacology (01.06.2021)
Published in Journal of clinical pharmacology (01.06.2021)
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Journal Article
Evolution of a Detailed Physiological Model to Simulate the Gastrointestinal Transit and Absorption Process in Humans, Part II: Extension to Describe Performance of Solid Dosage Forms
Thelen, Kirstin, Coboeken, Katrin, Willmann, Stefan, Dressman, Jennifer B., Lippert, Jörg
Published in Journal of pharmaceutical sciences (01.03.2012)
Published in Journal of pharmaceutical sciences (01.03.2012)
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Journal Article
Heart rate variability: reference values and role for clinical profile and mortality in individuals with heart failure
Zeid, Silav, Buch, Gregor, Velmeden, David, Söhne, Jakob, Schulz, Andreas, Schuch, Alexander, Tröbs, Sven-Oliver, Heidorn, Marc William, Müller, Felix, Strauch, Konstantin, Coboeken, Katrin, Lackner, Karl J., Gori, Tommaso, Münzel, Thomas, Prochaska, Jürgen H., Wild, Philipp S.
Published in Clinical research in cardiology (01.09.2024)
Published in Clinical research in cardiology (01.09.2024)
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Journal Article
Abstract 11025: Markers of Heart Rate Variability Represent Strong and Independent Predictors of All-Cause Death in Heart Failure - Results from the Myovasc Study
Zeid, Silav, Buch, Gregor, Velmeden, David, Soehne, Jakob, Schulz, Andreas, Schuch, Alexander, Troebs, Sven-Oliver, Heidorn, Marc, Mueller, Felix, Coboeken, Katrin, Lackner, Karl J, Gori, Tommaso, Muenzel, Thomas, Prochaska, Juergen H, Wild, Philipp
Published in Circulation (New York, N.Y.) (16.11.2021)
Published in Circulation (New York, N.Y.) (16.11.2021)
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Early prediction of decompensation (EPOD) score: Non‐invasive determination of cirrhosis decompensation risk
Schneider, Annika R. P., Schneider, Carolin V., Schneider, Kai Markus, Baier, Vanessa, Schaper, Steffen, Diedrich, Christian, Coboeken, Katrin, Mayer, Hannah, Gu, Wenyi, Trebicka, Jonel, Blank, Lars M., Burghaus, Rolf, Lippert, Joerg, Rader, Daniel J., Thaiss, Christoph A., Schlender, Jan‐Frederik, Trautwein, Christian, Kuepfer, Lars
Published in Liver international (01.03.2022)
Published in Liver international (01.03.2022)
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Journal Article
Contribution of rivaroxaban to the international normalized ratio when switching to warfarin for anticoagulation as determined by simulation studies
Siegmund, Hans‐Ulrich, Burghaus, Rolf, Kubitza, Dagmar, Coboeken, Katrin
Published in British journal of clinical pharmacology (01.06.2015)
Published in British journal of clinical pharmacology (01.06.2015)
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