A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy
Li, John Y., Perry, Samuel R., Muniz-Medina, Vanessa, Wang, Xinzhong, Wetzel, Leslie K., Rebelatto, Marlon C., Hinrichs, Mary Jane Masson, Bezabeh, Binyam Z., Fleming, Ryan L., Dimasi, Nazzareno, Feng, Hui, Toader, Dorin, Yuan, Andy Q., Xu, Lan, Lin, Jia, Gao, Changshou, Wu, Herren, Dixit, Rakesh, Osbourn, Jane K., Coats, Steven R.
Published in Cancer cell (11.01.2016)
Published in Cancer cell (11.01.2016)
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A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy
Li, John Y., Perry, Samuel R., Muniz-Medina, Vanessa, Wang, Xinzhong, Wetzel, Leslie K., Rebelatto, Marlon C., Masson Hinrichs, Mary Jane, Bezabeh, Binyam Z., Fleming, Ryan L., Dimasi, Nazzareno, Feng, Hui, Toader, Dorin, Yuan, Andy Q., Xu, Lan, Lin, Jia, Gao, Changshou, Wu, Herren, Dixit, Rakesh, Osbourn, Jane K., Coats, Steven R.
Published in Cancer cell (10.06.2019)
Published in Cancer cell (10.06.2019)
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The CEA/CD3-bispecific antibody MEDI-565 (MT111) binds a nonlinear epitope in the full-length but not a short splice variant of CEA
Peng, Li, Oberst, Michael D, Huang, Jiaqi, Brohawn, Philip, Morehouse, Chris, Lekstrom, Kristen, Baeuerle, Patrick A, Wu, Herren, Yao, Yihong, Coats, Steven R, Dall'Acqua, William, Damschroder, Melissa, Hammond, Scott A
Published in PloS one (04.05.2012)
Published in PloS one (04.05.2012)
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HER2-targeted antibody-drug conjugate induces host immunity against cancer stem cells
Xia, Leiming, Wen, Lu, Qin, You, Dobson, Hannah E., Zhang, Tao, Comer, Frank I., Hinrichs, Mary Jane, Oberst, Michael D., Coats, Steven R., Chang, Alfred E., Liu, Yuanyuan, Bao, Yangyi, Dai, Fu, Wicha, Max S., Li, Qiao
Published in Cell chemical biology (20.05.2021)
Published in Cell chemical biology (20.05.2021)
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Abstract LB-298: MEDI7247: A first in class antibody drug conjugate targeting ASCT2 in a range of solid tumors
Schifferli, Kevin P., Monks, Noel R., Tammali, Ravinder, Borrok, M Jack, Flynn, Matthew G., Hurt, Elaine M., Coats, Steven R., Herbst, Ronald, Tice, David A., Pore, Nabendu
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract LB-296: Discovery and development of MEDI7247, a novel Pyrrolobenzodiazepine (PBD)-based antibody drug conjugate targeting ASCT2, for treating hematological and solid cancers
Pore, Nabendu, Borrok, M Jack, Rebellato, Marlon, Hinrichs, MaryJane, Schifferli, Kevin P., Monks, Noel R., Tammali, Ravinder, Herbst, Ronald, Coats, Steven R., Tice, David A.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract LB-295: MEDI7247, a novel pyrrolobenzodiazepine ADC targeting ASCT2 with potent in vivo activity across a spectrum of hematological malignancies
Monks, Noel R., Schifferli, Kevin P., Tammali, Ravinder, Borrok, M. Jack, Coats, Steven R., Herbst, Ronald, Tice, David A., Pore, Nabendu
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 4981: HER2-targeted antibody drug conjugates (ADCs) induce host immunity against cancer stem cells and are enhanced by anti-PD-L1
Xia, Leiming, Wen, Lu, Wu, Gang, Zhang, Tao, Comer, Frank, Hinrichs, Mary Jane Masson, Oberst, Michael, Coats, Steven R., Chang, Alfred E., Liu, Yuanyuan, Bao, Yangyi, Wicha, Max, Li, Qiao
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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The CEA/CD3-Bispecific Antibody MEDI-565
Peng, Li, Oberst, Michael D, Huang, Jiaqi, Brohawn, Philip, Morehouse, Chris, Lekstrom, Kristen, Baeuerle, Patrick A, Wu, Herren, Yao, Yihong, Coats, Steven R, Dall'Acqua, William, Damschroder, Melissa, Hammond, Scott A
Published in PloS one (04.05.2012)
Published in PloS one (04.05.2012)
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Detergent solubility defines an alternative itinerary for a subpopulation of PDGF β receptors
Coats, Steven R., Pledger, Warren J., Awazu, Midori, Daniel, Thomas O.
Published in Journal of cellular physiology (01.08.1996)
Published in Journal of cellular physiology (01.08.1996)
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Characterization of the substance P receptor in guinea pig lung tissues
Coats, S R, Gerard, N P
Published in American journal of respiratory cell and molecular biology (01.10.1989)
Published in American journal of respiratory cell and molecular biology (01.10.1989)
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