4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro
WOODS, J. M, BETHELL, R. C, PENN, C. R, COATES, J. A. V, HEALY, N, HISCOX, S. A, PEARSON, B. A, RYAN, D. M, TICEHURST, J, TILLING, J, WALCOTT, S. M
Published in Antimicrobial Agents and Chemotherapy (01.07.1993)
Published in Antimicrobial Agents and Chemotherapy (01.07.1993)
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The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitro
Coates, J A, Cammack, N, Jenkinson, H J, Mutton, I M, Pearson, B A, Storer, R, Cameron, J M, Penn, C R
Published in Antimicrobial Agents and Chemotherapy (01.01.1992)
Published in Antimicrobial Agents and Chemotherapy (01.01.1992)
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Journal Article
(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro
COATES, J. A. V, CAMMACK, N, JENKINSON, H. J, JOWETT, A. J, JOWETT, M. I, PEARSON, B. A, PENN, C. R, ROUSE, P. L, CLAIRE VINER, K, CAMERON, J. M
Published in Antimicrobial Agents and Chemotherapy (01.04.1992)
Published in Antimicrobial Agents and Chemotherapy (01.04.1992)
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Journal Article
Cellular metabolism of (-) enantiomeric 2'-deoxy-3'-thiacytidine
Cammack, N, Rouse, P, Marr, C L, Reid, P J, Boehme, R E, Coates, J A, Penn, C R, Cameron, J M
Published in Biochemical pharmacology (28.05.1992)
Published in Biochemical pharmacology (28.05.1992)
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A novel class of 1,3-oxathiolane nucleoside analogues having potent anti-HIV activity
Belleau, Bernard, Brasili, Livio, Chan, Laval, DiMarco, Marika P., Zacharie, Boulos, Nguyen-Ba, Nghe, Jenkinson, Helen J., Coates, Jonathan A.V., Cameron, Janet M.
Published in Bioorganic & medicinal chemistry letters (01.08.1993)
Published in Bioorganic & medicinal chemistry letters (01.08.1993)
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Journal Article
Fluorocarbocyclic nucleosides : synthesis and antiviral activity of 2'- and 6'-fluorocarbocyclic 2'-deoxy guanosines
BORTHWICK, A. D, KIRK, B. E, BIGGADIKE, K, EXALL, A. M, BUTT, S, ROBERTS, S. M, KNIGHT, D. J, COATES, J. A. V, RYAN, D. M
Published in Journal of medicinal chemistry (01.03.1991)
Published in Journal of medicinal chemistry (01.03.1991)
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Journal Article
Constrained analogues of 2′-nor cyclic nucleoside monophosphates
Allan Tse, H.L., Knight, David J., Coates, Jonathan A.V., Mansour, Tarek S.
Published in Bioorganic & medicinal chemistry letters (03.06.1997)
Published in Bioorganic & medicinal chemistry letters (03.06.1997)
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Journal Article
Chiral carbocyclic nucleosides : the synthesis and antiviral activity of 4'-hydroxy and 4'-fluorocarbocyclic-2'-deoxyguanosines
BORTHWICK, A. D, BIGGADIKE, K, PATERNOSTER, I. L, COATES, J. A. V, KNIGHT, D. J
Published in Bioorganic & medicinal chemistry letters (01.12.1993)
Published in Bioorganic & medicinal chemistry letters (01.12.1993)
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Journal Article
Penicillin derived C sub(2)-symmetric dimers as novel inhibitors of HIV-1 proteinase
Humber, D C, Cammack, N, Coates, JAV, Cobley, K N, Orr, D C, Storer, R, Weingarten, G G, Weir, M P
Published in Journal of medicinal chemistry (01.01.1992)
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Published in Journal of medicinal chemistry (01.01.1992)
Journal Article
Fluorocarbocyclic nucleosides: Synthesis and antiviral activity of 2'- and 6'-fluorocarbocyclic pyrimidine nucleosides including carbocyclic 1-(2-deoxy-2-fluoro- beta -D-arabinofuranosyl)-5-methyluracil and carbocyclic 1-(2-deoxy-2-fluoro- beta -D-arabinofuranosyl)-5-iodouracil
Borthwick, AD, Evans, D N, Kirk, B E, Biggadike, K, Exall, A M, Youds, P, Roberts, S M, Knight, D J, Coates, JAV
Published in Journal of medicinal chemistry (01.01.1990)
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Published in Journal of medicinal chemistry (01.01.1990)
Journal Article
Stereochemical Aspects of the anti-HCMV Activity of Cytidine Nucleoside Analogues
Mansour, T. S., Cimpoia, A. R., Jin, H., Hunter, P. J., Evans, C. A., Tse, H. L. A., Gillard, J. W., Borthwick, A. D., Knight, D. J., Coates, J. A. V.
Published in Antiviral chemistry & chemotherapy (01.06.1995)
Published in Antiviral chemistry & chemotherapy (01.06.1995)
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PEPTIDIC COMPOUNDS
COATES, JONATHAN, ALAN, VICTOR JAV, PYNE, STEPHEN, GEOFFREY SG, RHODES, DAVID, IAN DI, MORGAN, JODY J, BOYLE, TIMOTHY, PATRICK TP, BRKIC, ZINKA Z, DALTON, NEAL, KEVIN NK, BREMNER, JOHN, BARNARD JB, ROBERTSON, MARK, JAMES MJ, KELLER, PAUL, ANTHONY PA, DEADMAN, JOHN J
Year of Publication 08.03.2013
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Year of Publication 08.03.2013
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