Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter
Fleming, Nicholas I, Knower, Kevin C, Lazarus, Kyren A, Fuller, Peter J, Simpson, Evan R, Clyne, Colin D
Published in PloS one (20.12.2010)
Published in PloS one (20.12.2010)
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Endocrine disruption of the epigenome: a breast cancer link
Knower, Kevin C, To, Sarah Q, Leung, Yuet-Kin, Ho, Shuk-Mei, Clyne, Colin D
Published in Endocrine-related cancer (01.04.2014)
Published in Endocrine-related cancer (01.04.2014)
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The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma
Coulson, Rhiannon, Liew, Seng H, Connelly, Angela A, Yee, Nicholas S, Deb, Siddhartha, Kumar, Beena, Vargas, Ana C, O'Toole, Sandra A, Parslow, Adam C, Poh, Ashleigh, Putoczki, Tracy, Morrow, Riley J, Alorro, Mariah, Lazarus, Kyren A, Yeap, Evie F W, Walton, Kelly L, Harrison, Craig A, Hannan, Natalie J, George, Amee J, Clyne, Colin D, Ernst, Matthias, Allen, Andrew M, Chand, Ashwini L
Published in Oncotarget (21.03.2017)
Published in Oncotarget (21.03.2017)
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A tumour suppressive relationship between mineralocorticoid and retinoic acid receptors activates a transcriptional program consistent with a reverse Warburg effect in breast cancer
Doan, Tram B, Cheung, Vanessa, Clyne, Colin D, Hilton, Heidi N, Eriksson, Natalie, Young, Morag J, Funder, John W, Muscat, George E O, Fuller, Peter J, Clarke, Christine L, Graham, J Dinny
Published in Breast cancer research : BCR (04.11.2020)
Published in Breast cancer research : BCR (04.11.2020)
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GEMIN4 functions as a coregulator of the mineralocorticoid receptor
Yang, Jun, Fuller, Peter J, Morgan, James, Shibata, Hirotaka, Clyne, Colin D, Young, Morag J
Published in Journal of molecular endocrinology (01.04.2015)
Published in Journal of molecular endocrinology (01.04.2015)
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The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferation
Chand, Ashwini L, Wijayakumara, Dhilushi D, Knower, Kevin C, Herridge, Kerrie A, Howard, Tamara L, Lazarus, Kyren A, Clyne, Colin D
Published in PloS one (16.02.2012)
Published in PloS one (16.02.2012)
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Distinct nuclear receptor expression in stroma adjacent to breast tumors
Knower, Kevin C., Chand, Ashwini L., Eriksson, Natalie, Takagi, Kiyoshi, Miki, Yasuhiro, Sasano, Hironobu, Visvader, Jane E., Lindeman, Geoffrey J., Funder, John W., Fuller, Peter J., Simpson, Evan R., Tilley, Wayne D., Leedman, Peter J., Graham, J. Dinny, Muscat, George E. O., Clarke, Christine L., Clyne, Colin D.
Published in Breast cancer research and treatment (01.11.2013)
Published in Breast cancer research and treatment (01.11.2013)
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Identification of Ligand-Selective Peptide Antagonists of the Mineralocorticoid Receptor Using Phage Display
Yang, Jun, Chang, Ching-yi, Safi, Rachid, Morgan, James, McDonnell, Donald P, Fuller, Peter J, Clyne, Colin D, Young, Morag J
Published in Molecular endocrinology (Baltimore, Md.) (01.01.2011)
Published in Molecular endocrinology (Baltimore, Md.) (01.01.2011)
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Liver Receptor Homologue-1 (LRH-1) Regulates Expression of Aromatase in Preadipocytes
Clyne, Colin D., Speed, Caroline J., Zhou, Jiong, Simpson, Evan R.
Published in The Journal of biological chemistry (07.06.2002)
Published in The Journal of biological chemistry (07.06.2002)
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Epigenetic mechanisms regulating CYP19 transcription in human breast adipose fibroblasts
Knower, Kevin C., To, Sarah Q., Simpson, Evan R., Clyne, Colin D.
Published in Molecular and cellular endocrinology (10.06.2010)
Published in Molecular and cellular endocrinology (10.06.2010)
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Hepatic glucose intolerance precedes hepatic steatosis in the male aromatase knockout (ArKO) mouse
Van Sinderen, Michelle L, Steinberg, Gregory R, Jørgensen, Sebastian B, To, Sarah Q, Knower, Kevin C, Clyne, Colin D, Honeyman, Jane, Chow, Jenny D, Herridge, Kerrie A, Jones, Margaret E E, Simpson, Evan R, Boon, Wah Chin
Published in PloS one (10.02.2014)
Published in PloS one (10.02.2014)
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Interactions between prostaglandin E2, liver receptor homologue-1, and aromatase in breast cancer
JIONG ZHOU, SUZUKI, Takashi, KOVACIC, Agnes, SAITO, Ryoko, MIKI, Yasuhiro, ISHIDA, Takanori, MORIYA, Takuya, SIMPSON, Evan R, SASANO, Hironobu, CLYNE, Colin D
Published in Cancer research (Chicago, Ill.) (15.01.2005)
Published in Cancer research (Chicago, Ill.) (15.01.2005)
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Epigenetic mechanisms regulate the prostaglandin E receptor 2 in breast cancer
To, Sarah Q., Takagi, Kiyoshi, Miki, Yasuhiro, Suzuki, Koyu, Abe, Eriko, Yang, Yang, Sasano, Hironobu, Simpson, Evan R., Knower, Kevin C., Clyne, Colin D.
Published in The Journal of steroid biochemistry and molecular biology (01.11.2012)
Published in The Journal of steroid biochemistry and molecular biology (01.11.2012)
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