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Cloughesy, Timothy F, Cavenee, Webster K, Mischel, Paul S
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Ivosidenib in Isocitrate Dehydrogenase 1 - Mutated Advanced Glioma
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Vorasidenib, a Dual Inhibitor of Mutant IDH1/2, in Recurrent or Progressive Glioma; Results of a First-in-Human Phase I Trial
Mellinghoff, Ingo K, Penas-Prado, Marta, Peters, Katherine B, Burris, 3rd, Howard A, Maher, Elizabeth A, Janku, Filip, Cote, Gregory M, de la Fuente, Macarena I, Clarke, Jennifer L, Ellingson, Benjamin M, Chun, Saewon, Young, Robert J, Liu, Hua, Choe, Sung, Lu, Min, Le, Kha, Hassan, Islam, Steelman, Lori, Pandya, Shuchi S, Cloughesy, Timothy F, Wen, Patrick Y
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Published in Clinical cancer research (15.08.2021)
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Infigratinib in Patients with Recurrent Gliomas and FGFR Alterations: A Multicenter Phase II Study
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Published in Clinical cancer research (01.06.2022)
Published in Clinical cancer research (01.06.2022)
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Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma
Mellinghoff, Ingo K., van den Bent, Martin J., Blumenthal, Deborah T., Touat, Mehdi, Peters, Katherine B., Clarke, Jennifer, Mendez, Joe, Yust-Katz, Shlomit, Welsh, Liam, Mason, Warren P., Ducray, François, Umemura, Yoshie, Nabors, Burt, Holdhoff, Matthias, Hottinger, Andreas F., Arakawa, Yoshiki, Sepulveda, Juan M., Wick, Wolfgang, Soffietti, Riccardo, Perry, James R., Giglio, Pierre, de la Fuente, Macarena, Maher, Elizabeth A., Schoenfeld, Steven, Zhao, Dan, Pandya, Shuchi S., Steelman, Lori, Hassan, Islam, Wen, Patrick Y., Cloughesy, Timothy F.
Published in The New England journal of medicine (17.08.2023)
Published in The New England journal of medicine (17.08.2023)
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Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
Bi, Junfeng, Ichu, Taka-Aki, Zanca, Ciro, Yang, Huijun, Zhang, Wei, Gu, Yuchao, Chowdhry, Sudhir, Reed, Alex, Ikegami, Shiro, Turner, Kristen M., Zhang, Wenjing, Villa, Genaro R., Wu, Sihan, Quehenberger, Oswald, Yong, William H., Kornblum, Harley I., Rich, Jeremy N., Cloughesy, Timothy F., Cavenee, Webster K., Furnari, Frank B., Cravatt, Benjamin F., Mischel, Paul S.
Published in Cell metabolism (03.09.2019)
Published in Cell metabolism (03.09.2019)
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EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling
Liu, Feng, Hon, Gary C., Villa, Genaro R., Turner, Kristen M., Ikegami, Shiro, Yang, Huijun, Ye, Zhen, Li, Bin, Kuan, Samantha, Lee, Ah Young, Zanca, Ciro, Wei, Bowen, Lucey, Greg, Jenkins, David, Zhang, Wei, Barr, Cathy L., Furnari, Frank B., Cloughesy, Timothy F., Yong, William H., Gahman, Timothy C., Shiau, Andrew K., Cavenee, Webster K., Ren, Bing, Mischel, Paul S.
Published in Molecular cell (15.10.2015)
Published in Molecular cell (15.10.2015)
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Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study
Butowski, Nicholas, Colman, Howard, De Groot, John F, Omuro, Antonio M, Nayak, Lakshmi, Wen, Patrick Y, Cloughesy, Timothy F, Marimuthu, Adhirai, Haidar, Sam, Perry, Arie, Huse, Jason, Phillips, Joanna, West, Brian L, Nolop, Keith B, Hsu, Henry H, Ligon, Keith L, Molinaro, Annette M, Prados, Michael
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Published in Neuro-oncology (Charlottesville, Va.) (01.04.2016)
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mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT
Gu, Yuchao, Albuquerque, Claudio P., Braas, Daniel, Zhang, Wei, Villa, Genaro R., Bi, Junfeng, Ikegami, Shiro, Masui, Kenta, Gini, Beatrice, Yang, Huijun, Gahman, Timothy C., Shiau, Andrew K., Cloughesy, Timothy F., Christofk, Heather R., Zhou, Huilin, Guan, Kun-Liang, Mischel, Paul S.
Published in Molecular cell (06.07.2017)
Published in Molecular cell (06.07.2017)
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2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling
Fu, Xudong, Chin, Randall M., Vergnes, Laurent, Hwang, Heejun, Deng, Gang, Xing, Yanpeng, Pai, Melody Y., Li, Sichen, Ta, Lisa, Fazlollahi, Farbod, Chen, Chuo, Prins, Robert M., Teitell, Michael A., Nathanson, David A., Lai, Albert, Faull, Kym F., Jiang, Meisheng, Clarke, Steven G., Cloughesy, Timothy F., Graeber, Thomas G., Braas, Daniel, Christofk, Heather R., Jung, Michael E., Reue, Karen, Huang, Jing
Published in Cell metabolism (01.09.2015)
Published in Cell metabolism (01.09.2015)
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Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA
Nathanson, David A., Gini, Beatrice, Mottahedeh, Jack, Visnyei, Koppany, Koga, Tomoyuki, Gomez, German, Estin, Ascia, Hwang, Kiwook, Wang, Jun, Masui, Kenta, Paucar, Andres, Yang, Huijun, Ohashi, Minori, Zhu, Shaojun, Wykosky, Jill, Reed, Rachel, Nelson, Stanley F., Cloughesy, Timothy F., James, C. David, Rao, P. Nagesh, Kornblum, Harley I., Heath, James R., Cavenee, Webster K., Furnari, Frank B., Mischel, Paul S.
Published in Science (American Association for the Advancement of Science) (03.01.2014)
Published in Science (American Association for the Advancement of Science) (03.01.2014)
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Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma
Chinot, Olivier L, Wick, Wolfgang, Mason, Warren, Henriksson, Roger, Saran, Frank, Nishikawa, Ryo, Carpentier, Antoine F, Hoang-Xuan, Khe, Kavan, Petr, Cernea, Dana, Brandes, Alba A, Hilton, Magalie, Abrey, Lauren, Cloughesy, Timothy
Published in The New England journal of medicine (20.02.2014)
Published in The New England journal of medicine (20.02.2014)
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Vorasidenib and ivosidenib in IDH1-mutant low-grade glioma: a randomized, perioperative phase 1 trial
Mellinghoff, Ingo K., Lu, Min, Wen, Patrick Y., Taylor, Jennie W., Maher, Elizabeth A., Arrillaga-Romany, Isabel, Peters, Katherine B., Ellingson, Benjamin M., Rosenblum, Marc K., Chun, Saewon, Le, Kha, Tassinari, Ania, Choe, Sung, Toubouti, Youssef, Schoenfeld, Steven, Pandya, Shuchi S., Hassan, Islam, Steelman, Lori, Clarke, Jennifer L., Cloughesy, Timothy F.
Published in Nature medicine (01.03.2023)
Published in Nature medicine (01.03.2023)
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Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial
Wen, Patrick Y, Touat, Mehdi, Alexander, Brian M, Mellinghoff, Ingo K, Ramkissoon, Shakti, McCluskey, Christine S, Pelton, Kristine, Haidar, Sam, Basu, Sankha S, Gaffey, Sarah C, Brown, Loreal E, Martinez-Ledesma, Juan Emmanuel, Wu, Shaofang, Kim, Jungwoo, Wei, Wei, Park, Mi-Ae, Huse, Jason T, Kuhn, John G, Rinne, Mikael L, Colman, Howard, Agar, Nathalie Y R, Omuro, Antonio M, DeAngelis, Lisa M, Gilbert, Mark R, de Groot, John F, Cloughesy, Timothy F, Chi, Andrew S, Roberts, Thomas M, Zhao, Jean J, Lee, Eudocia Q, Nayak, Lakshmi, Heath, James R, Horky, Laura L, Batchelor, Tracy T, Beroukhim, Rameen, Chang, Susan M, Ligon, Azra H, Dunn, Ian F, Koul, Dimpy, Young, Geoffrey S, Prados, Michael D, Reardon, David A, Yung, W K Alfred, Ligon, Keith L
Published in Journal of clinical oncology (20.03.2019)
Published in Journal of clinical oncology (20.03.2019)
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