Subcutaneous delivery of daratumumab in relapsed or refractory multiple myeloma
Usmani, Saad Z., Nahi, Hareth, Mateos, Maria-Victoria, van de Donk, Niels W.C.J., Chari, Ajai, Kaufman, Jonathan L., Moreau, Philippe, Oriol, Albert, Plesner, Torben, Benboubker, Lotfi, Hellemans, Peter, Masterson, Tara, Clemens, Pamela L., Luo, Man, Liu, Kevin, San-Miguel, Jesus
Published in Blood (22.08.2019)
Published in Blood (22.08.2019)
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Phase 1/2 study of daratumumab, lenalidomide, and dexamethasone for relapsed multiple myeloma
Plesner, Torben, Arkenau, Hendrik-Tobias, Gimsing, Peter, Krejcik, Jakub, Lemech, Charlotte, Minnema, Monique C., Lassen, Ulrik, Laubach, Jacob P., Palumbo, Antonio, Lisby, Steen, Basse, Linda, Wang, Jianping, Sasser, A. Kate, Guckert, Mary E., de Boer, Carla, Khokhar, Nushmia Z., Yeh, Howard, Clemens, Pamela L., Ahmadi, Tahamtan, Lokhorst, Henk M., Richardson, Paul G.
Published in Blood (06.10.2016)
Published in Blood (06.10.2016)
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Effects of daratumumab on natural killer cells and impact on clinical outcomes in relapsed or refractory multiple myeloma
Casneuf, Tineke, Xu, Xu Steven, Adams, Homer C., Axel, Amy E., Chiu, Christopher, Khan, Imran, Ahmadi, Tahamtan, Yan, Xiaoyu, Lonial, Sagar, Plesner, Torben, Lokhorst, Henk M., van de Donk, Niels W.C.J., Clemens, Pamela L., Sasser, A. Kate
Published in Blood advances (24.10.2017)
Published in Blood advances (24.10.2017)
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Daratumumab plus carfilzomib and dexamethasone in patients with relapsed or refractory multiple myeloma
Chari, Ajai, Martinez-Lopez, Joaquín, Mateos, María-Victoria, Bladé, Joan, Benboubker, Lotfi, Oriol, Albert, Arnulf, Bertrand, Rodriguez-Otero, Paula, Pineiro, Luis, Jakubowiak, Andrzej, de Boer, Carla, Wang, Jianping, Clemens, Pamela L., Ukropec, Jon, Schecter, Jordan, Lonial, Sagar, Moreau, Philippe
Published in Blood (01.08.2019)
Published in Blood (01.08.2019)
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Pharmacokinetics of Daratumumab Following Intravenous Infusion in Relapsed or Refractory Multiple Myeloma After Prior Proteasome Inhibitor and Immunomodulatory Drug Treatment
Clemens, Pamela L., Yan, Xiaoyu, Lokhorst, Henk M., Lonial, Sagar, Losic, Nedjad, Khan, Imran, Jansson, Richard, Ahmadi, Tahamtan, Lantz, Kristen, Zhou, Honghui, Puchalski, Thomas, Xu, Xu Steven
Published in Clinical pharmacokinetics (01.08.2017)
Published in Clinical pharmacokinetics (01.08.2017)
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Daratumumab monotherapy for patients with intermediate-risk or high-risk smoldering multiple myeloma: a randomized, open-label, multicenter, phase 2 study (CENTAURUS)
Landgren, C. Ola, Chari, Ajai, Cohen, Yael C., Spencer, Andrew, Voorhees, Peter, Estell, Jane A., Sandhu, Irwindeep, Jenner, Matthew W., Williams, Catherine, Cavo, Michele, van de Donk, Niels W. C. J., Beksac, Meral, Moreau, Philippe, Goldschmidt, Hartmut, Kuppens, Steven, Bandekar, Rajesh, Clemens, Pamela L., Neff, Tobias, Heuck, Christoph, Qi, Ming, Hofmeister, Craig C.
Published in Leukemia (01.07.2020)
Published in Leukemia (01.07.2020)
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Subcutaneous versus intravenous daratumumab in patients with relapsed or refractory multiple myeloma (COLUMBA): a multicentre, open-label, non-inferiority, randomised, phase 3 trial
Mateos, Maria-Victoria, Nahi, Hareth, Legiec, Wojciech, Grosicki, Sebastian, Vorobyev, Vladimir, Spicka, Ivan, Hungria, Vania, Korenkova, Sibirina, Bahlis, Nizar, Flogegard, Max, Bladé, Joan, Moreau, Philippe, Kaiser, Martin, Iida, Shinsuke, Laubach, Jacob, Magen, Hila, Cavo, Michele, Hulin, Cyrille, White, Darrell, De Stefano, Valerio, Clemens, Pamela L, Masterson, Tara, Lantz, Kristen, O'Rourke, Lisa, Heuck, Christoph, Qin, Xiang, Parasrampuria, Dolly A, Yuan, Zhilong, Xu, Steven, Qi, Ming, Usmani, Saad Z
Published in The Lancet. Haematology (01.05.2020)
Published in The Lancet. Haematology (01.05.2020)
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Monitoring multiple myeloma patients treated with daratumumab: teasing out monoclonal antibody interference
McCudden, Christopher, Axel, Amy E, Slaets, Dominique, Dejoie, Thomas, Clemens, Pamela L, Frans, Sandy, Bald, Jaime, Plesner, Torben, Jacobs, Joannes F M, van de Donk, Niels W C J, Moreau, Philippe, Schecter, Jordan M, Ahmadi, Tahamtan, Sasser, A Kate
Published in Clinical chemistry and laboratory medicine (01.06.2016)
Published in Clinical chemistry and laboratory medicine (01.06.2016)
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Subcutaneous Versus Intravenous Amivantamab, Both in Combination With Lazertinib, in Refractory Epidermal Growth Factor Receptor–Mutated Non–Small Cell Lung Cancer: Primary Results From the Phase III PALOMA-3 Study
Leighl, Natasha B., Akamatsu, Hiroaki, Lim, Sun Min, Cheng, Ying, Minchom, Anna R., Marmarelis, Melina E., Sanborn, Rachel E., Chih-Hsin Yang, James, Liu, Baogang, John, Thomas, Massutí, Bartomeu, Spira, Alexander I., Lee, Se-Hoon, Wang, Jialei, Li, Juan, Liu, Caigang, Novello, Silvia, Kondo, Masashi, Tamiya, Motohiro, Korbenfeld, Ernesto, Moskovitz, Mor, Han, Ji-Youn, Alexander, Mariam, Joshi, Rohit, Felip, Enriqueta, Voon, Pei Jye, Danchaivijitr, Pongwut, Hsu, Ping-Chih, Silva Melo Cruz, Felipe José, Wehler, Thomas, Greillier, Laurent, Teixeira, Encarnação, Nguyen, Danny, Sabari, Joshua K., Qin, Angel, Kowalski, Dariusz, Şendur, Mehmet Ali Nahit, Xie, John, Ghosh, Debopriya, Alhadab, Ali, Haddish-Berhane, Nahor, Clemens, Pamela L., Lorenzini, Patricia, Verheijen, Remy B., Gamil, Mohamed, Bauml, Joshua M., Baig, Mahadi, Passaro, Antonio, Akamatsu, Hiroaki, Alexander, Mariam, Bleckmann, Annalen, Cappuzzo, Federico, Cheng, Ying, Cho, Byoung Chul, Cil, Timucin, Cortot, Alexis, Danchaivijitr, Pongwut, Emde, Till-Oliver, Erdem, Dilek, Felip, Enriqueta, Estevinho, Fernanda, Lurdes Ferreira, Maria, da Silva, Flavio Ferreira, Garcia Campelo, Maria del Rosario, Greillier, Laurent, Greystoke, Alastair, Han, Ji-Youn, Hsu, Ping-Chih, Hung, Jen-Yu, Ji, Mei, John, Thomas, Joshi, Rohit, Kim, Young-Chul, Kondo, Masashi, Korbenfeld, Ernesto, Kowalski, Dariusz, Lee, Se-Hoon, Leighl, Natasha, Li, Juan, Lin, Sheng-Hao, Liu, Baogang, Liu, Caigang, Seng-Hooi Low, John, Marmarelis, Melina E., Massutí, Bartomeu, Minchom, Anna R., Moore, Sara, Moskovitz, Mor, Nagrial, Adnan, Nguyen, Danny, Novello, Silvia, Ohe, Yuichiro, Özgüroğlu, Mustafa, Ozyilkan, Ozgur, Passaro, Antonio, Peled, Nir, Prasongsook, Naiyarat, Qin, Angel, Ramos, Elisa F., Sabari, Joshua K.
Published in Journal of clinical oncology (20.10.2024)
Published in Journal of clinical oncology (20.10.2024)
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Influence of Disease and Patient Characteristics on Daratumumab Exposure and Clinical Outcomes in Relapsed or Refractory Multiple Myeloma
Yan, Xiaoyu, Clemens, Pamela L., Puchalski, Thomas, Lonial, Sagar, Lokhorst, Henk, Voorhees, Peter M., Usmani, Saad, Richardson, Paul G., Plesner, Torben, Liu, Kevin, Orlowski, Robert Z., Losic, Nedjad, Jansson, Richard, Ahmadi, Tahamtan, Lantz, Kristen, Ruixo, Juan Jose Perez, Zhou, Honghui, Xu, Xu Steven
Published in Clinical pharmacokinetics (01.04.2018)
Published in Clinical pharmacokinetics (01.04.2018)
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Split First Dose Administration of Intravenous Daratumumab for the Treatment of Multiple Myeloma (MM): Clinical and Population Pharmacokinetic Analyses
Xu, Xu Steven, Moreau, Philippe, Usmani, Saad Z., Lonial, Sagar, Jakubowiak, Andrzej, Oriol, Albert, Krishnan, Amrita, Bladé, Joan, Luo, Man, Sun, Yu-Nien, Zhou, Honghui, Nnane, Ivo, Deraedt, William, Qi, Ming, Ukropec, Jon, Clemens, Pamela L.
Published in Advances in therapy (01.04.2020)
Published in Advances in therapy (01.04.2020)
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Evaluation of Cardiac Repolarization in the Randomized Phase 2 Study of Intermediate- or High-Risk Smoldering Multiple Myeloma Patients Treated with Daratumumab Monotherapy
Chari, Ajai, Munder, Markus, Weisel, Katja, Jenner, Matthew, Bygrave, Ceri, Petrucci, Maria Teresa, Boccadoro, Mario, Cavo, Michele, van de Donk, Niels W. C. J., Turgut, Mehmet, Demirkan, Fatih, Karadogan, Ihsan, Libby, Edward, Kleiman, Robert, Kuppens, Steven, Bandekar, Rajesh, Neff, Tobias, Heuck, Christoph, Qi, Ming, Clemens, Pamela L., Goldschmidt, Hartmut
Published in Advances in therapy (01.02.2021)
Published in Advances in therapy (01.02.2021)
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Pharmacokinetics and Exposure–Response Analyses of Daratumumab in Combination Therapy Regimens for Patients with Multiple Myeloma
Xu, Xu Steven, Dimopoulos, Meletios A., Sonneveld, Pieter, Ho, P. Joy, Belch, Andrew, Leiba, Merav, Capra, Marcelo, Gomez, David, Medvedova, Eva, Iida, Shinsuke, Min, Chang-Ki, Schecter, Jordan, Jansson, Richard, Zhang, Liping, Sun, Yu-Nien, Clemens, Pamela L.
Published in Advances in therapy (01.11.2018)
Published in Advances in therapy (01.11.2018)
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Subcutaneous daratumumab in patients with relapsed or refractory multiple myeloma: Part 2 of the open-label, multicenter, dose-escalation phase 1b study (PAVO)
San-Miguel, Jesus, Usmani, Saad Z, Mateos, Maria-Victoria, van de Donk, Niels W C J, Kaufman, Jonathan L, Moreau, Philippe, Oriol, Albert, Plesner, Torben, Benboubker, Lotfi, Liu, Kevin, Hellemans, Peter, Masterson, Tara, Clemens, Pamela L, Luo, Man, Farnsworth, Andrew, Nahi, Hareth, Chari, Ajai
Published in Haematologica (Roma) (30.04.2020)
Published in Haematologica (Roma) (30.04.2020)
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Lack of effect of brivanib on the pharmacokinetics of midazolam, a CYP3A4 substrate, administered intravenously and orally in healthy participants
Syed, Shariq, Clemens, Pamela L, Lathers, Deanne, Kollia, Georgia, Dhar, Arindam, Walters, Ian, Masson, Eric
Published in Journal of clinical pharmacology (01.06.2012)
Published in Journal of clinical pharmacology (01.06.2012)
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A phase I study of oral ixabepilone in patients with advanced solid tumors
Deeken, John F., Marshall, John L., Pishvaian, Michael J., Hwang, Jimmy, Ahlers, Christoph M., Clemens, Pamela L., Parker, Susan M., Iacono, Lisa, LoRusso, Patricia M.
Published in Cancer chemotherapy and pharmacology (01.05.2014)
Published in Cancer chemotherapy and pharmacology (01.05.2014)
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Metabolism and Disposition of [14C]BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor Inhibitor, after Oral Administration to Humans
CHRISTOPHER, Lisa J, HAIZHENG HONG, LYER, Ramaswamy A, HUMPHREYS, William G, TAI WONG, ZHANG, Steven, VAKKALAGADDA, Blisse J, CLEMENS, Pamela L, HONG SU, ROONGTA, Vikram, ALLENTOFF, Alban, HAOJUN SUN, HELLER, Kevin, HARBISON, Christopher T
Published in Drug metabolism and disposition (01.11.2010)
Published in Drug metabolism and disposition (01.11.2010)
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Phase I trial of ixabepilone administered as three oral doses each separated by 6 hours every 3 weeks in patients with advanced solid tumors
Kunz, Pamela L., He, Aiwu R., Colevas, A. Dimitrios, Pishvaian, Michael J., Hwang, Jimmy J., Clemens, Pamela L., Messina, Marianne, Kaleta, Remigiusz, Abrahao, Fernanda, Sikic, Branimir I., Marshall, John L.
Published in Investigational new drugs (01.12.2012)
Published in Investigational new drugs (01.12.2012)
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Subcutaneous daratumumab in patients with relapsed or refractory multiple myeloma: part 2 of the open-label, multicenter, dose-escalation phase Ib study (PAVO)
San-Miguel, Jesus, Usmani, Saad Z., Mateos, Maria-Victoria, van de Donk, Niels W.C.J., Kaufman, Jonathan L., Moreau, Philippe, Oriol, Albert, Plesner, Torben, Benboubker, Lotfi, Liu, Kevin, Hellemans, Peter, Masterson, Tara, Clemens, Pamela L., Luo, Man, Farnsworth, Andrew, Nahi, Hareth, Chari, Ajai
Published in Haematologica (Roma) (01.06.2021)
Published in Haematologica (Roma) (01.06.2021)
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