Modulation of hERG K + Channel Deactivation by Voltage Sensor Relaxation
Shi, Yu Patrick, Thouta, Samrat, Claydon, Thomas W
Published in Frontiers in pharmacology (28.02.2020)
Published in Frontiers in pharmacology (28.02.2020)
Get full text
Journal Article
hiPSC-derived cardiomyocytes as a model to study the role of small-conductance Ca2+-activated K+ (SK) ion channel variants associated with atrial fibrillation
Babini, Hosna, Jiménez-Sábado, Verónica, Stogova, Ekaterina, Arslanova, Alia, Butt, Mariam, Dababneh, Saif, Asghari, Parisa, Moore, Edwin D. W., Claydon, Thomas W., Chiamvimonvat, Nipavan, Hove-Madsen, Leif, Tibbits, Glen F.
Published in Frontiers in cell and developmental biology (18.01.2024)
Published in Frontiers in cell and developmental biology (18.01.2024)
Get full text
Journal Article
An Activation Gating Switch in Kv1.2 Is Localized to a Threonine Residue in the S2-S3 Linker
Rezazadeh, Saman, Kurata, Harley T., Claydon, Thomas W., Kehl, Steven J., Fedida, David
Published in Biophysical journal (15.12.2007)
Published in Biophysical journal (15.12.2007)
Get full text
Journal Article
KN-93 (2-[N-(2-Hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine), a Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor, Is a Direct Extracellular Blocker of Voltage-Gated Potassium Channels
Rezazadeh, Saman, Claydon, Thomas W, Fedida, David
Published in The Journal of pharmacology and experimental therapeutics (01.04.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2006)
Get full text
Journal Article
4-Aminopyridine Prevents the Conformational Changes Associated with P/C-Type Inactivation in Shaker Channels
Claydon, Thomas W, Vaid, Moni, Rezazadeh, Saman, Kehl, Steven J, Fedida, David
Published in The Journal of pharmacology and experimental therapeutics (01.01.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2007)
Get full text
Journal Article
Zebrafish cardiac repolarization does not functionally depend on the expression of the hERG1b-like transcript
Genge, Christine E., Muralidharan, Padmapriya, Kemp, Jake, Hull, Christina M., Yip, Mandy, Simpson, Kyle, Hunter, Diana V., Claydon, Thomas W.
Published in Pflügers Archiv (2024)
Published in Pflügers Archiv (2024)
Get full text
Journal Article
Molecular Basis of Ion Selectivity, Block, and Rectification of the Inward Rectifier Kir3.1/Kir3.4 K+ Channel
Dibb, Katherine M., Rose, Thierry, Makary, Samy Y., Claydon, Thomas W., Enkvetchakul, Decha, Leach, Robert, Nichols, Colin G., Boyett, Mark R.
Published in The Journal of biological chemistry (05.12.2003)
Published in The Journal of biological chemistry (05.12.2003)
Get full text
Journal Article
Electrophysiological characterization of the hERG R56Q LQTS variant and targeted rescue by the activator RPR260243
Kemp, Jacob M, Whittaker, Dominic G, Venkateshappa, Ravichandra, Pang, ZhaoKai, Johal, Raj, Sergeev, Valentine, Tibbits, Glen F, Mirams, Gary R, Claydon, Thomas W
Published in The Journal of general physiology (04.10.2021)
Published in The Journal of general physiology (04.10.2021)
Get full text
Journal Article
The hERG channel activator, RPR260243, enhances protective IKr current early in the refractory period reducing arrhythmogenicity in zebrafish hearts
Shi, Yu Patrick, Pang, ZhaoKai, Venkateshappa, Ravichandra, Gunawan, Marvin, Kemp, Jacob, Truong, Elson, Chang, Cherlene, Lin, Eric, Shafaattalab, Sanam, Faizi, Shoaib, Rayani, Kaveh, Tibbits, Glen F, Claydon, Victoria E, Claydon, Thomas W
Published in American journal of physiology. Heart and circulatory physiology (01.08.2020)
Published in American journal of physiology. Heart and circulatory physiology (01.08.2020)
Get full text
Journal Article
CRISPR-Cas9-mediated Precise Knock-in Edits in Zebrafish Hearts
Simpson, Kyle E, Faizi, Shoaib, Venkateshappa, Ravichandra, Yip, Mandy, Johal, Raj, Poburko, Damon, Cheng, Yen May, Hunter, Diana, Lin, Eric, Tibbits, Glen F, Claydon, Thomas W
Published in Journal of visualized experiments (13.09.2022)
Published in Journal of visualized experiments (13.09.2022)
Get full text
Journal Article
Functional characterization of a novel hERG variant in a family with recurrent sudden infant death syndrome: Retracting a genetic diagnosis
Sergeev, Valentine, Perry, Frances, Roston, Thomas M., Sanatani, Shubhayan, Tibbits, Glen F., Claydon, Thomas W.
Published in Forensic science international (01.03.2018)
Published in Forensic science international (01.03.2018)
Get full text
Journal Article
The Zebrafish Heart as a Model of Mammalian Cardiac Function
Genge, Christine E, Lin, Eric, Lee, Ling, Sheng, XiaoYe, Rayani, Kaveh, Gunawan, Marvin, Stevens, Charles M, Li, Alison Yueh, Talab, Sanam Shafaat, Claydon, Thomas W, Hove-Madsen, Leif, Tibbits, Glen F
Published in Reviews of physiology, biochemistry and pharmacology (01.01.2016)
Published in Reviews of physiology, biochemistry and pharmacology (01.01.2016)
Get more information
Journal Article
A direct demonstration of closed-state inactivation of K+ channels at low pH
Claydon, Thomas W, Vaid, Moni, Rezazadeh, Saman, Kwan, Daniel C H, Kehl, Steven J, Fedida, David
Published in The Journal of general physiology (01.05.2007)
Published in The Journal of general physiology (01.05.2007)
Get full text
Journal Article
Block by internal Mg2+ causes voltage-dependent inactivation of Kv1.5
Claydon, Thomas W, Kwan, Daniel C H, Fedida, David, Kehl, Steven J
Published in European biophysics journal (01.12.2006)
Published in European biophysics journal (01.12.2006)
Get full text
Journal Article