Electronic Absorption Spectra from MM and ab Initio QM/MM Molecular Dynamics: Environmental Effects on the Absorption Spectrum of Photoactive Yellow Protein
Isborn, Christine M, Götz, Andreas W, Clark, Matthew A, Walker, Ross C, Martínez, Todd J
Published in Journal of chemical theory and computation (11.12.2012)
Published in Journal of chemical theory and computation (11.12.2012)
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Journal Article
Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library
Litovchick, Alexander, Dumelin, Christoph E., Habeshian, Sevan, Gikunju, Diana, Guié, Marie-Aude, Centrella, Paolo, Zhang, Ying, Sigel, Eric A., Cuozzo, John W., Keefe, Anthony D., Clark, Matthew A.
Published in Scientific reports (10.06.2015)
Published in Scientific reports (10.06.2015)
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Journal Article
Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry
Litovchick, Alexander, Tian, Xia, Monteiro, Michael I, Kennedy, Kaitlyn M, Guié, Marie-Aude, Centrella, Paolo, Zhang, Ying, Clark, Matthew A, Keefe, Anthony D
Published in Molecules (Basel, Switzerland) (27.05.2019)
Published in Molecules (Basel, Switzerland) (27.05.2019)
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Journal Article
Fast Motions of Key Methyl Groups in Amyloid-β Fibrils
Vugmeyster, Liliya, Ostrovsky, Dmitry, Clark, Matthew A., Falconer, Isaac B., Hoatson, Gina L., Qiang, Wei
Published in Biophysical journal (15.11.2016)
Published in Biophysical journal (15.11.2016)
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Journal Article
Chemical ligation methods for the tagging of DNA-encoded chemical libraries
Keefe, Anthony D, Clark, Matthew A, Hupp, Christopher D, Litovchick, Alexander, Zhang, Ying
Published in Current opinion in chemical biology (01.06.2015)
Published in Current opinion in chemical biology (01.06.2015)
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Journal Article
Trading Utility for Privacy in Shared Spectrum Access Systems
Clark, Matthew A., Psounis, Konstantinos
Published in IEEE/ACM transactions on networking (01.02.2018)
Published in IEEE/ACM transactions on networking (01.02.2018)
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Journal Article
An extensible interface for QM/MM molecular dynamics simulations with AMBER
Götz, Andreas W., Clark, Matthew A., Walker, Ross C.
Published in Journal of computational chemistry (15.01.2014)
Published in Journal of computational chemistry (15.01.2014)
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Journal Article
Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry
Cuozzo, John W, Clark, Matthew A, Keefe, Anthony D, Kohlmann, Anna, Mulvihill, Mark, Ni, Haihong, Renzetti, Louis M, Resnicow, Daniel I, Ruebsam, Frank, Sigel, Eric A, Thomson, Heather A, Wang, Ce, Xie, Zhifeng, Zhang, Ying
Published in Journal of medicinal chemistry (23.07.2020)
Published in Journal of medicinal chemistry (23.07.2020)
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Journal Article
Soft-Tissue Sarcomas in Adults
Clark, Matthew A, Fisher, Cyril, Judson, Ian, Thomas, J. Meirion
Published in The New England journal of medicine (18.08.2005)
Published in The New England journal of medicine (18.08.2005)
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Journal Article
Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding
McCloskey, Kevin, Sigel, Eric A, Kearnes, Steven, Xue, Ling, Tian, Xia, Moccia, Dennis, Gikunju, Diana, Bazzaz, Sana, Chan, Betty, Clark, Matthew A, Cuozzo, John W, Guié, Marie-Aude, Guilinger, John P, Huguet, Christelle, Hupp, Christopher D, Keefe, Anthony D, Mulhern, Christopher J, Zhang, Ying, Riley, Patrick
Published in Journal of medicinal chemistry (27.08.2020)
Published in Journal of medicinal chemistry (27.08.2020)
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Journal Article
Screening Ultra-Large Encoded Compound Libraries Leads to Novel Protein–Ligand Interactions and High Selectivity
Collie, Gavin W., Clark, Matthew A., Keefe, Anthony D., Madin, Andrew, Read, Jon A., Rivers, Emma L., Zhang, Ying
Published in Journal of medicinal chemistry (25.01.2024)
Published in Journal of medicinal chemistry (25.01.2024)
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Journal Article
Flexibility and Solvation of Amyloid-β Hydrophobic Core
Vugmeyster, Liliya, Clark, Matthew A., Falconer, Isaac B., Ostrovsky, Dmitry, Gantz, Donald, Qiang, Wei, Hoatson, Gina L.
Published in The Journal of biological chemistry (26.08.2016)
Published in The Journal of biological chemistry (26.08.2016)
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Journal Article
Development and Synthesis of DNA-Encoded Benzimidazole Library
Ding, Yun, Chai, Jing, Centrella, Paolo A, Gondo, Chenaimwoyo, DeLorey, Jennifer L, Clark, Matthew A
Published in ACS combinatorial science (14.05.2018)
Published in ACS combinatorial science (14.05.2018)
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Journal Article
Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening
Disch, Jeremy S, Duffy, Jennifer M, Lee, Esther C. Y, Gikunju, Diana, Chan, Betty, Levin, Benjamin, Monteiro, Michael I, Talcott, Sarah A, Lau, Anthony C, Zhou, Fei, Kozhushnyan, Anton, Westlund, Neil E, Mullins, Patrick B, Yu, Yan, von Rechenberg, Moritz, Zhang, Junyi, Arnautova, Yelena A, Liu, Yanbin, Zhang, Ying, McRiner, Andrew J, Keefe, Anthony D, Kohlmann, Anna, Clark, Matthew A, Cuozzo, John W, Huguet, Christelle, Arora, Shilpi
Published in Journal of medicinal chemistry (22.04.2021)
Published in Journal of medicinal chemistry (22.04.2021)
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Journal Article
Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA‐Encoded Chemical Library
Cuozzo, John W., Centrella, Paolo A., Gikunju, Diana, Habeshian, Sevan, Hupp, Christopher D., Keefe, Anthony D., Sigel, Eric A., Soutter, Holly H., Thomson, Heather A., Zhang, Ying, Clark, Matthew A.
Published in Chembiochem : a European journal of chemical biology (04.05.2017)
Published in Chembiochem : a European journal of chemical biology (04.05.2017)
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Journal Article
Ribociclib mitigates cisplatin-associated kidney injury through retinoblastoma-1 dependent mechanisms
Kim, Ji Young, Jayne, Laura A., Bai, Yuntao, Feng, Mei Ji He Ho, Clark, Matthew A., Chung, Sangwoon, W. Christman, John, Cianciolo, Rachel E., Pabla, Navjot Singh
Published in Biochemical pharmacology (01.07.2020)
Published in Biochemical pharmacology (01.07.2020)
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Journal Article
Design, synthesis and selection of DNA-encoded small-molecule libraries
Morgan, Barry A, Clark, Matthew A, Acharya, Raksha A, Arico-Muendel, Christopher C, Belyanskaya, Svetlana L, Benjamin, Dennis R, Carlson, Neil R, Centrella, Paolo A, Chiu, Cynthia H, Creaser, Steffen P, Cuozzo, John W, Davie, Christopher P, Ding, Yun, Franklin, G Joseph, Franzen, Kurt D, Gefter, Malcolm L, Hale, Steven P, Hansen, Nils J V, Israel, David I, Jiang, Jinwei, Kavarana, Malcolm J, Kelley, Michael S, Kollmann, Christopher S, Li, Fan, Lind, Kenneth, Mataruse, Sibongile, Medeiros, Patricia F, Messer, Jeffrey A, Myers, Paul, O'Keefe, Heather, Oliff, Matthew C, Rise, Cecil E, Satz, Alexander L, Skinner, Steven R, Svendsen, Jennifer L, Tang, Lujia, van Vloten, Kurt, Wagner, Richard W, Yao, Gang, Zhao, Baoguang
Published in Nature Chemical Biology (01.09.2009)
Published in Nature Chemical Biology (01.09.2009)
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