Poly (ADP-ribose) polymerase inhibitors: recent advances and future development
Scott, Clare L, Swisher, Elizabeth M, Kaufmann, Scott H
Published in Journal of clinical oncology (20.04.2015)
Published in Journal of clinical oncology (20.04.2015)
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Journal Article
Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial
Ledermann, Jonathan, Prof, Harter, Philipp, MD, Gourley, Charlie, Prof, Friedlander, Michael, Prof, Vergote, Ignace, Prof, Rustin, Gordon, Prof, Scott, Clare L, PhD, Meier, Werner, Prof, Shapira-Frommer, Ronnie, MD, Safra, Tamar, MD, Matei, Daniela, MD, Fielding, Anitra, MBChB, Spencer, Stuart, MSc, Dougherty, Brian, PhD, Orr, Maria, PhD, Hodgson, Darren, PhD, Barrett, J Carl, PhD, Matulonis, Ursula, MD
Published in The lancet oncology (01.07.2014)
Published in The lancet oncology (01.07.2014)
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Journal Article
DNA Damage-Induced Primordial Follicle Oocyte Apoptosis and Loss of Fertility Require TAp63-Mediated Induction of Puma and Noxa
Kerr, Jeffrey B., Hutt, Karla J., Michalak, Ewa M., Cook, Michele, Vandenberg, Cassandra J., Liew, Seng H., Bouillet, Philippe, Mills, Alea, Scott, Clare L., Findlay, Jock K., Strasser, Andreas
Published in Molecular cell (09.11.2012)
Published in Molecular cell (09.11.2012)
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Journal Article
p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa
Valente, Liz J., Gray, Daniel H.D., Michalak, Ewa M., Pinon-Hofbauer, Josefina, Egle, Alex, Scott, Clare L., Janic, Ana, Strasser, Andreas
Published in Cell reports (Cambridge) (30.05.2013)
Published in Cell reports (Cambridge) (30.05.2013)
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Journal Article
Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility
Nguyen, Quynh-Nhu, Zerafa, Nadeen, Liew, Seng H., Morgan, F. Hamish, Strasser, Andreas, Scott, Clare L., Findlay, Jock K., Hickey, Martha, Hutt, Karla J.
Published in Cell death & disease (23.05.2018)
Published in Cell death & disease (23.05.2018)
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Journal Article
Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics
Cragg, Mark S, Scott, Clare L, Harris, Claire, Strasser, Andreas
Published in Nature reviews. Cancer (01.05.2009)
Published in Nature reviews. Cancer (01.05.2009)
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Journal Article
T-Cell Receptor Therapy in the Treatment of Ovarian Cancer: A Mini Review
Wu, Jessica W Y, Dand, Sudiksha, Doig, Lachlan, Papenfuss, Anthony T, Scott, Clare L, Ho, Gwo, Ooi, Joshua D
Published in Frontiers in immunology (13.04.2021)
Published in Frontiers in immunology (13.04.2021)
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Journal Article
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
van Delft, Mark F., Wei, Andrew H., Mason, Kylie D., Vandenberg, Cassandra J., Chen, Lin, Czabotar, Peter E., Willis, Simon N., Scott, Clare L., Day, Catherine L., Cory, Suzanne, Adams, Jerry M., Roberts, Andrew W., Huang, David C.S.
Published in Cancer cell (01.11.2006)
Published in Cancer cell (01.11.2006)
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Journal Article
Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance
Campbell, Kirsteen J., Bath, Mary L., Turner, Marian L., Vandenberg, Cassandra J., Bouillet, Philippe, Metcalf, Donald, Scott, Clare L., Cory, Suzanne
Published in Blood (28.10.2010)
Published in Blood (28.10.2010)
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Journal Article
Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells
Valente, Liz J., Aubrey, Brandon J., Herold, Marco J., Kelly, Gemma L., Happo, Lina, Scott, Clare L., Newbold, Andrea, Johnstone, Ricky W., Huang, David C.S., Vassilev, Lyubomir T., Strasser, Andreas
Published in Cell reports (Cambridge) (01.03.2016)
Published in Cell reports (Cambridge) (01.03.2016)
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Journal Article
Molecular correlates of platinum response in human high-grade serous ovarian cancer patient-derived xenografts
Topp, Monique D., Hartley, Lynne, Cook, Michele, Heong, Valerie, Boehm, Emma, McShane, Lauren, Pyman, Jan, McNally, Orla, Ananda, Sumitra, Harrell, Marisol, Etemadmoghadam, Dariush, Galletta, Laura, Alsop, Kathryn, Mitchell, Gillian, Fox, Stephen B., Kerr, Jeffrey B., Hutt, Karla J., Kaufmann, Scott H., Australian Ovarian Cancer Study, Swisher, Elizabeth M., Bowtell, David D., Wakefield, Matthew J., Scott, Clare L.
Published in Molecular oncology (01.05.2014)
Published in Molecular oncology (01.05.2014)
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Journal Article
High-level tumour methylation of BRCA1 and RAD51C is required for homologous recombination deficiency in solid cancers
Xu, Lijun, Liddell, Brett, Nesic, Ksenija, Geissler, Franziska, Ashwood, Lauren M, Wakefield, Matthew J, Scott, Clare L, Waddell, Nicola, Kondrashova, Olga
Published in NAR cancer (01.09.2024)
Published in NAR cancer (01.09.2024)
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Journal Article
The role of aberrant DNA methylation in cancer initiation and clinical impacts
Geissler, Franziska, Nesic, Ksenija, Kondrashova, Olga, Dobrovic, Alexander, Swisher, Elizabeth M, Scott, Clare L, J Wakefield, Matthew
Published in Therapeutic advances in medical oncology (01.01.2024)
Published in Therapeutic advances in medical oncology (01.01.2024)
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Journal Article
In vivo Efficacy of the Bcl-2 Antagonist ABT-737 against Aggressive Myc-Driven Lymphomas
Mason, Kylie D., Vandenberg, Cassandra J., Scott, Clare L., Wei, Andrew H., Cory, Suzanne, Huang, David C. S., Roberts, Andrew W.
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2008)
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Journal Article
Role of the chromobox protein CBX7 in lymphomagenesis
Scott, Clare L, Gil, Jésus, Hernando, Eva, Teruya-Feldstein, Julie, Narita, Masako, Martínez, Dolores, Visakorpi, Tapio, Mu, David, Cordon-Cardo, Carlos, Peters, Gordon, Beach, David, Lowe, Scott W
Published in Proceedings of the National Academy of Sciences - PNAS (27.03.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (27.03.2007)
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Journal Article
Insights into ovarian cancer care: report from the ANZGOG Ovarian Cancer Webinar Series 2020
Obermair, Andreas, Beale, Philip, Scott, Clare L, Beshay, Victoria, Kichenadasse, Ganessan, Simcock, Bryony, Nicklin, James, Lee, Yeh Chen, Cohen, Paul, Meniawy, Tarek
Published in Journal of gynecologic oncology (01.11.2021)
Published in Journal of gynecologic oncology (01.11.2021)
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Journal Article
PUMA regulates germ cell loss and primordial follicle endowment in mice
Myers, Michelle, Morgan, F Hamish, Liew, Seng H, Zerafa, Nadeen, Gamage, Thilini Upeksha, Sarraj, Mai, Cook, Michele, Kapic, Ileana, Sutherland, Antony, Scott, Clare L, Strasser, Andreas, Findlay, Jock K, Kerr, Jeffrey B, Hutt, Karla J
Published in Reproduction (Cambridge, England) (01.08.2014)
Published in Reproduction (Cambridge, England) (01.08.2014)
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Journal Article
Dual roles for Id4 in the regulation of estrogen signaling in the mammary gland and ovary
Best, Sarah A, Hutt, Karla J, Fu, Nai Yang, Vaillant, François, Liew, Seng H, Hartley, Lynne, Scott, Clare L, Lindeman, Geoffrey J, Visvader, Jane E
Published in Development (Cambridge) (01.08.2014)
Published in Development (Cambridge) (01.08.2014)
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Journal Article
BCL2-modifying factor promotes germ cell loss during murine oogenesis
Vaithiyanathan, Kavitha, Liew, Seng H, Zerafa, Nadeen, Gamage, Thilini, Cook, Michele, O’Reilly, Lorraine A, Bouillet, Philippe, Scott, Clare L, Strasser, Andreas, Findlay, Jock K, Hutt, Karla J
Published in Reproduction (Cambridge, England) (01.05.2016)
Published in Reproduction (Cambridge, England) (01.05.2016)
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Journal Article