Anti‐rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen‐induced arthritis in rodents
Lin, H‐S, Hu, C‐Y, Chan, H‐Y, Liew, Y‐Y, Huang, H‐P, Lepescheux, L, Bastianelli, E, Baron, R, Rawadi, G, Clément‐Lacroix, P
Published in British journal of pharmacology (01.04.2007)
Published in British journal of pharmacology (01.04.2007)
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Journal Article
Androgen replacement therapy improves function in male rat muscles independently of hypertrophy and activation of the Akt/mTOR pathway
Hourdé, C., Jagerschmidt, C., Clément-Lacroix, P., Vignaud, A., Ammann, P., Butler-Browne, G. S., Ferry, A.
Published in Acta Physiologica (01.04.2009)
Published in Acta Physiologica (01.04.2009)
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Osteoblasts are a new target for prolactin: analysis of bone formation in prolactin receptor knockout mice
Clément-Lacroix, P, Ormandy, C, Lepescheux, L, Ammann, P, Damotte, D, Goffin, V, Bouchard, B, Amling, M, Gaillard-Kelly, M, Binart, N, Baron, R, Kelly, P A
Published in Endocrinology (Philadelphia) (01.01.1999)
Published in Endocrinology (Philadelphia) (01.01.1999)
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Journal Article
A new selective estrogen receptor modulator HMR-3339 fully corrects bone alterations induced by ovariectomy in adult rats
Ammann, P, Bourrin, S, Brunner, F, Meyer, J.-M, Clément-Lacroix, P, Baron, R, Gaillard, M, Rizzoli, R
Published in Bone (New York, N.Y.) (01.07.2004)
Published in Bone (New York, N.Y.) (01.07.2004)
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Journal Article
THU0138 Glpg0634m1, A Major Metabolite of the Jak1-Selective Inhibitor Glpg0634, is Also Jak1-Selective and Efficient in the Rat CIA Model
Belleville-Da-Costa, C., Merciris, D., Vayssière, B., Houvenaghel, N., Monjardet, A., Lepescheux, L., Dupont, S., Christophe, T., Borgonovi, M., Clément-Lacroix, P., Menet, C., Van Rompaey, L., Brys, R., Galien, R.
Published in Annals of the rheumatic diseases (01.06.2014)
Published in Annals of the rheumatic diseases (01.06.2014)
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Journal Article
Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5
Sims, N A, Clément-Lacroix, P, Da Ponte, F, Bouali, Y, Binart, N, Moriggl, R, Goffin, V, Coschigano, K, Gaillard-Kelly, M, Kopchick, J, Baron, R, Kelly, P A
Published in The Journal of clinical investigation (01.11.2000)
Published in The Journal of clinical investigation (01.11.2000)
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Journal Article
GLPG0187 inhibits progression of established bone metastasis and achieves maximum efficacy when combined with standard-of-care metastatic breast cancer treatments
Clément-Lacroix, P, Berrocal, E, Heckmann, B, Wigerinck, P, Lorenzon, G, Pujuguet, P
Published in Bone (New York, N.Y.) (01.01.2011)
Published in Bone (New York, N.Y.) (01.01.2011)
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Journal Article
Rescue of preimplantatory egg development and embryo implantation in prolactin receptor-deficient mice after progesterone administration
Binart, N, Helloco, C, Ormandy, C J, Barra, J, Clément-Lacroix, P, Baran, N, Kelly, P A
Published in Endocrinology (Philadelphia) (01.07.2000)
Published in Endocrinology (Philadelphia) (01.07.2000)
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Journal Article
PP 87 Molecular imaging demonstrates GLPG0187, a small-molecule integrin antagonist, binds to RGD-integrin receptors in vivo and is efficacious in tumor and metastasis models
Pujuguet, P, Berrocal, E, Heckmann, B, Wigerinck, P, Lorenzon, G, Clément-Lacroix, P, Bormans, G, Deroose, C
Published in European journal of cancer (1990) (2011)
Published in European journal of cancer (1990) (2011)
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Journal Article
Pharmacological characterization of GLPG1972/S201086, a potent and selective small-molecule inhibitor of ADAMTS5
Clement-Lacroix, P., Little, C.B., Smith, M.M., Cottereaux, C., Merciris, D., Meurisse, S., Mollat, P., Touitou, R., Brebion, F., Gosmini, R., De Ceuninck, F., Botez, I., Lepescheux, L., van der Aar, E., Christophe, T., Vandervoort, N., Blanqué, R., Comas, D., Deprez, P., Amantini, D.
Published in Osteoarthritis and cartilage (01.02.2022)
Published in Osteoarthritis and cartilage (01.02.2022)
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Journal Article
350 IRAK4 drives pathogenic processes in inflammatory skin diseases
Jargosch, M., Lavazais, S., Ohm, F., Jagerschmidt, C., Fallon, P., Clément-Lacroix, P., Lauffer, F., Brys, R., Eyerich, K.
Published in Journal of investigative dermatology (01.12.2022)
Published in Journal of investigative dermatology (01.12.2022)
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Journal Article
OP0258 Efficacy of the highly selective adamts-5 inhibitor glpg1972 in the rat meniscectomy model
Lepescheux, L., Clement-Lacroix, P., Merciris, D., Meurisse, S., Borgonovi, M., Cottereaux, C., Mollat, P., Brebion, F., Gosmini, R., De Ceuninck, F., Botez, I., van der Aar, E., Christophe, T., Vandervoort, N., Blanqué, R., Comas, D., Deprez, P., Amantini, D.
Published in Annals of the rheumatic diseases (01.06.2018)
Published in Annals of the rheumatic diseases (01.06.2018)
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Journal Article
Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-β in bone remodeling in females but not in males
SIMS, N. A, DUPONT, S, KRUST, A, CLEMENT-LACROIX, P, MINET, D, RESCHE-RIGON, M, GAILLARD-KELLY, M, BARON, R
Published in Bone (New York, N.Y.) (2002)
Published in Bone (New York, N.Y.) (2002)
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Journal Article
GLPG1972: a potent, selective, orally available adamts-5 inhibitor for the treatment of OA
Clement-Lacroix, P, Little, C, Meurisse, S, Blanqué, R, Mollat, P, Brebion, F, Gosmini, R, De Ceuninck, F, Botez, I, Lepescheux, L, van der Aar, E, Christophe, T, Vandervoort, N, Cottereaux, C, Comas, D, Deprez, P, Amantini, D
Published in Osteoarthritis and cartilage (01.04.2017)
Published in Osteoarthritis and cartilage (01.04.2017)
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Journal Article
New cartilage quality evaluation using bio-indentation: effect of a tool dmoad compound active in the rat MNX model
Lavet, C, Clement-Lacroix, P, Merciris, D, Meurisse, S, Lepescheux, L, Gaillard, V, Pastoureau, P, Deprez, P, Amantini, D, Ammann, P
Published in Osteoarthritis and cartilage (01.04.2016)
Published in Osteoarthritis and cartilage (01.04.2016)
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Journal Article
THU0116 Biological Effects of the JAK1 Selective Inhibitor GLPG0634 on Inflammation Markers in Arthritic Mice
Vayssiere, B., de Vos, S., Merciris, D., Auberval, M., Dupont, S., Vandeghinste, N., Lepescheux, L., Clement-Lacroix, P., Delerive, P., van Rompaey, L., Brys, R., Galien, R.
Published in Annals of the rheumatic diseases (01.06.2013)
Published in Annals of the rheumatic diseases (01.06.2013)
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Journal Article
Up-regulation of a set of genes in breast cancer bone metastases discloses predisposition to generate metastases also in visceral organs
Rucci, N, Capulli, M, Angelucci, A, Martella, F, Bologna, M, Ventura, L, Moreschini, O, Driouch, K, Landemaine, T, Lidereau, R, Clement-Lacroix, P, Garcia, T, Ricevuto, E, Teti, A
Published in Bone (New York, N.Y.) (01.05.2011)
Published in Bone (New York, N.Y.) (01.05.2011)
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Journal Article
From the molecular biology of prolactin and its receptor to the lessons learned from knockout mice models
Goffin, Vincent, Binart, Nadine, Clément-Lacroix, Philippe, Bouchard, Brigitte, Bole-Feysot, Christine, Edery, Marc, Lucas, Brian K, Touraine, Philippe, Pezet, Alain, Maaskant, Ronda, Pichard, Caroline, Helloco, Christine, Baran, Nathalie, Favre, Hélène, Bernichtein, Sophie, Allamando, Angélique, Ormandy, Christopher, Kelly, Paul A
Published in Genetic analysis : biomolecular engineering (01.11.1999)
Published in Genetic analysis : biomolecular engineering (01.11.1999)
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