Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion
Cimino, Irene, Casoni, Filippo, Liu, Xinhuai, Messina, Andrea, Parkash, Jyoti, Jamin, Soazik P., Catteau-Jonard, Sophie, Collier, Francis, Baroncini, Marc, Dewailly, Didier, Pigny, Pascal, Prescott, Mel, Campbell, Rebecca, Herbison, Allan E., Prevot, Vincent, Giacobini, Paolo
Published in Nature communications (12.01.2016)
Published in Nature communications (12.01.2016)
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Journal Article
Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells
Yang, Ming, Darwish, Tamana, Larraufie, Pierre, Rimmington, Debra, Cimino, Irene, Goldspink, Deborah A., Jenkins, Benjamin, Koulman, Albert, Brighton, Cheryl A., Ma, Marcella, Lam, Brian Y. H., Coll, Anthony P., O’Rahilly, Stephen, Reimann, Frank, Gribble, Fiona M.
Published in Scientific reports (28.01.2021)
Published in Scientific reports (28.01.2021)
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Journal Article
Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence
Parkash, Jyoti, Messina, Andrea, Langlet, Fanny, Cimino, Irene, Loyens, Anne, Mazur, Danièle, Gallet, Sarah, Balland, Eglantine, Malone, Samuel A., Pralong, François, Cagnoni, Gabriella, Schellino, Roberta, De Marchis, Silvia, Mazzone, Massimiliano, Pasterkamp, R. Jeroen, Tamagnone, Luca, Prevot, Vincent, Giacobini, Paolo
Published in Nature communications (27.02.2015)
Published in Nature communications (27.02.2015)
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Journal Article
The gastrointestinal tract is a major source of the acute metformin-stimulated rise in GDF15
Kincaid, John W. R., Rimmington, Debra, Tadross, John A., Cimino, Irene, Zvetkova, Ilona, Kaser, Arthur, Richards, Paul, Patel, Satish, O’Rahilly, Stephen, Coll, Anthony P.
Published in Scientific reports (22.01.2024)
Published in Scientific reports (22.01.2024)
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Journal Article
HypoMap—a unified single-cell gene expression atlas of the murine hypothalamus
Steuernagel, Lukas, Lam, Brian Y. H., Klemm, Paul, Dowsett, Georgina K. C., Bauder, Corinna A., Tadross, John A., Hitschfeld, Tamara Sotelo, del Rio Martin, Almudena, Chen, Weiyi, de Solis, Alain J., Fenselau, Henning, Davidsen, Peter, Cimino, Irene, Kohnke, Sara N., Rimmington, Debra, Coll, Anthony P., Beyer, Andreas, Yeo, Giles S. H., Brüning, Jens C.
Published in Nature metabolism (01.10.2022)
Published in Nature metabolism (01.10.2022)
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Journal Article
Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing
Lam, Brian Y.H, Cimino, Irene, Polex-Wolf, Joseph, Nicole Kohnke, Sara, Rimmington, Debra, Iyemere, Valentine, Heeley, Nicholas, Cossetti, Chiara, Schulte, Reiner, Saraiva, Luis R, Logan, Darren W, Blouet, Clemence, O'Rahilly, Stephen, Coll, Anthony P, Yeo, Giles S.H
Published in Molecular metabolism (Germany) (01.05.2017)
Published in Molecular metabolism (Germany) (01.05.2017)
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Journal Article
Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism
Malone, Samuel Andrew, Papadakis, Georgios E, Messina, Andrea, Mimouni, Nour El Houda, Trova, Sara, Imbernon, Monica, Allet, Cecile, Cimino, Irene, Acierno, James, Cassatella, Daniele, Xu, Cheng, Quinton, Richard, Szinnai, Gabor, Pigny, Pascal, Alonso-Cotchico, Lur, Masgrau, Laura, Maréchal, Jean-Didier, Prevot, Vincent, Pitteloud, Nelly, Giacobini, Paolo
Published in eLife (10.07.2019)
Published in eLife (10.07.2019)
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Journal Article
A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing
Dowsett, Georgina K.C., Lam, Brian Y.H., Tadross, John A., Cimino, Irene, Rimmington, Debra, Coll, Anthony P., Polex-Wolf, Joseph, Knudsen, Lotte Bjerre, Pyke, Charles, Yeo, Giles S.H.
Published in Molecular metabolism (Germany) (01.11.2021)
Published in Molecular metabolism (Germany) (01.11.2021)
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Journal Article
Trappc9 deficiency causes parent-of-origin dependent microcephaly and obesity
Liang, Zhengzheng S, Cimino, Irene, Yalcin, Binnaz, Raghupathy, Narayanan, Vancollie, Valerie E, Ibarra-Soria, Ximena, Firth, Helen V, Rimmington, Debra, Farooqi, I Sadaf, Lelliott, Christopher J, Munger, Steven C, O'Rahilly, Stephen, Ferguson-Smith, Anne C, Coll, Anthony P, Logan, Darren W
Published in PLoS genetics (02.09.2020)
Published in PLoS genetics (02.09.2020)
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Journal Article
Opposite-sex attraction in male mice requires testosterone-dependent regulation of adult olfactory bulb neurogenesis
Schellino, Roberta, Trova, Sara, Cimino, Irene, Farinetti, Alice, Jongbloets, Bart C., Pasterkamp, R. Jeroen, Panzica, Giancarlo, Giacobini, Paolo, De Marchis, Silvia, Peretto, Paolo
Published in Scientific reports (26.10.2016)
Published in Scientific reports (26.10.2016)
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Journal Article
p140Cap Controls Female Fertility in Mice Acting via Glutamatergic Afference on Hypothalamic Gonadotropin-Releasing Hormone Neurons
Camera, Mattia, Russo, Isabella, Zamboni, Valentina, Ammoni, Alessandra, Rando, Simona, Morellato, Alessandro, Cimino, Irene, Angelini, Costanza, Giacobini, Paolo, Oleari, Roberto, Amoruso, Federica, Cariboni, Anna, Franceschini, Isabelle, Turco, Emilia, Defilippi, Paola, Merlo, Giorgio R
Published in Frontiers in neuroscience (14.02.2022)
Published in Frontiers in neuroscience (14.02.2022)
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Journal Article
Anti-Mullerian hormone: an ovarian hormone exerting hypothalamic feedback?
Catteau-Jonard, Sophie, Dewailly, Didier, Prévot, Vincent, Cimino, Irène, Giacobini, Paolo
Published in M.S. Médecine sciences (01.05.2016)
Published in M.S. Médecine sciences (01.05.2016)
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Journal Article
The role of GDF15 in food intake and appetitive behaviour
Cimino, Irene, Coll, Anthony P.
Published in Current opinion in endocrine and metabolic research (01.02.2022)
Published in Current opinion in endocrine and metabolic research (01.02.2022)
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Journal Article
GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans
Patel, Satish, Alvarez-Guaita, Anna, Melvin, Audrey, Rimmington, Debra, Dattilo, Alessia, Miedzybrodzka, Emily L., Cimino, Irene, Maurin, Anne-Catherine, Roberts, Geoffrey P., Meek, Claire L., Virtue, Samuel, Sparks, Lauren M., Parsons, Stephanie A., Redman, Leanne M., Bray, George A., Liou, Alice P., Woods, Rachel M., Parry, Sion A., Jeppesen, Per B., Kolnes, Anders J., Harding, Heather P., Ron, David, Vidal-Puig, Antonio, Reimann, Frank, Gribble, Fiona M., Hulston, Carl J., Farooqi, I. Sadaf, Fafournoux, Pierre, Smith, Steven R., Jensen, Jorgen, Breen, Danna, Wu, Zhidan, Zhang, Bei B., Coll, Anthony P., Savage, David B., O’Rahilly, Stephen
Published in Cell metabolism (05.03.2019)
Published in Cell metabolism (05.03.2019)
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Journal Article
GDF15 mediates the effects of metformin on body weight and energy balance
Coll, Anthony P., Chen, Michael, Taskar, Pranali, Rimmington, Debra, Patel, Satish, Tadross, John A., Cimino, Irene, Yang, Ming, Welsh, Paul, Virtue, Samuel, Goldspink, Deborah A., Miedzybrodzka, Emily L., Konopka, Adam R., Esponda, Raul Ruiz, Huang, Jeffrey T.-J., Tung, Y. C. Loraine, Rodriguez-Cuenca, Sergio, Tomaz, Rute A., Harding, Heather P., Melvin, Audrey, Yeo, Giles S. H., Preiss, David, Vidal-Puig, Antonio, Vallier, Ludovic, Nair, K. Sreekumaran, Wareham, Nicholas J., Ron, David, Gribble, Fiona M., Reimann, Frank, Sattar, Naveed, Savage, David B., Allan, Bernard B., O’Rahilly, Stephen
Published in Nature (London) (20.02.2020)
Published in Nature (London) (20.02.2020)
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Journal Article
Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15
Cimino, Irene, Kim, Hanna, Tung, Y. C. Loraine, Pedersen, Kent, Rimmington, Debra, Tadross, John A., Kohnke, Sara N., Neves-Costa, Ana, Barros, André, Joaquim, Stephanie, Bennett, Don, Melvin, Audrey, Lockhart, Samuel M., Rostron, Anthony J., Scott, Jonathan, Liu, Hui, Burling, Keith, Barker, Peter, Clatworthy, Menna R., Lee, E-Chiang, Simpson, A. John, Yeo, Giles S. H., Moita, Luís F., Bence, Kendra K., Jørgensen, Sebastian Beck, Coll, Anthony P., Breen, Danna M., O’Rahilly, Stephen
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.2021)
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Journal Article
Suppression of β1-integrin in gonadotropin-releasing hormone cells disrupts migration and axonal extension resulting in severe reproductive alterations
Parkash, Jyoti, Cimino, Irene, Ferraris, Nicoletta, Casoni, Filippo, Wray, Susan, Cappy, Hélène, Prevot, Vincent, Giacobini, Paolo
Published in The Journal of neuroscience (21.11.2012)
Published in The Journal of neuroscience (21.11.2012)
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Journal Article
GDF15 신호전달의 치료적 억제제
O'RAHILLY STEPHEN, COLL ANTHONY PATRICK, LEE E CHIANG, CIMINO IRENE, LIU HUI, CARPENTER ADAM
Year of Publication 05.12.2023
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Year of Publication 05.12.2023
Patent
Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity
Cimino, Irene, Rimmington, Debra, Tung, Y. C. Loraine, Lawler, Katherine, Larraufie, Pierre, Kay, Richard G., Virtue, Samuel, Lam, Brian Y. H., Fagnocchi, Luca, Ma, Marcella K. L., Saudek, Vladimir, Zvetkova, Ilona, Vidal-Puig, Antonio, Yeo, Giles S. H., Farooqi, I. Sadaf, Pospisilik, J. Andrew, Gribble, Fiona M., Reimann, Frank, O’Rahilly, Stephen, Coll, Anthony P.
Published in Scientific reports (02.09.2021)
Published in Scientific reports (02.09.2021)
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Journal Article