Dynamic balance of pro‐ and anti‐inflammatory signals controls disease and limits pathology
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Published in Immunological reviews (01.09.2018)
Published in Immunological reviews (01.09.2018)
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Th17 cytokines differentiate obesity from obesity‐associated type 2 diabetes and promote TNFα production
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Published in Obesity (Silver Spring, Md.) (01.01.2016)
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Multi-scale modeling predicts a balance of tumor necrosis factor-α and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection
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Published in PloS one (15.07.2013)
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M281, an Anti‐FcRn Antibody: Pharmacodynamics, Pharmacokinetics, and Safety Across the Full Range of IgG Reduction in a First‐in‐Human Study
Ling, Leona E., Hillson, Jan L., Tiessen, Renger G., Bosje, Tjerk, Iersel, Mattheus Paulus, Nix, Darrell J., Markowitz, Lynn, Cilfone, Nicholas A., Duffner, Jay, Streisand, James B., Manning, Anthony M., Arroyo, Santiago
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Published in Clinical pharmacology and therapeutics (01.04.2019)
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Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium
Ricard, Nicolas, Scott, Rizaldy P, Booth, Carmen J, Velazquez, Heino, Cilfone, Nicholas A, Baylon, Javier L, Gulcher, Jeffrey R, Quaggin, Susan E, Chittenden, Thomas W, Simons, Michael
Published in The Journal of experimental medicine (05.08.2019)
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Chronic mTOR activation induces a degradative smooth muscle cell phenotype
Li, Guangxin, Wang, Mo, Caulk, Alexander W, Cilfone, Nicholas A, Gujja, Sharvari, Qin, Lingfeng, Chen, Pei-Yu, Chen, Zehua, Yousef, Sameh, Jiao, Yang, He, Changshun, Jiang, Bo, Korneva, Arina, Bersi, Matthew R, Wang, Guilin, Liu, Xinran, Mehta, Sameet, Geirsson, Arnar, Gulcher, Jeffrey R, Chittenden, Thomas W, Simons, Michael, Humphrey, Jay D, Tellides, George
Published in The Journal of clinical investigation (01.03.2020)
Published in The Journal of clinical investigation (01.03.2020)
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Th17 Cytokines Differentiate Obesity from Obesity-Associated Type 2 Diabetes and Promote TNF[Alpha] Production
Ip, Blanche, Cilfone, Nicholas A, Belkina, Anna C, DeFuria, Jason, Jagannathan-Bogdan, Madhumita, Zhu, Min, Kuchibhatla, Ramya, McDonnell, Marie E, Xiao, Qiang, Kepler, Thomas B, Apovian, Caroline M, Lauffenburger, Douglas A, Nikolajczyk, Barbara S
Published in Obesity (Silver Spring, Md.) (01.01.2016)
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Enhancing reproducibility of gene expression analysis with known protein functional relationships: The concept of well-associated protein
Pradines, Joël R, Farutin, Victor, Cilfone, Nicholas A, Ghavami, Abouzar, Kurtagic, Elma, Guess, Jamey, Manning, Anthony M, Capila, Ishan
Published in PLoS computational biology (14.02.2020)
Published in PLoS computational biology (14.02.2020)
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Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis
Chen, Pei-Yu, Qin, Lingfeng, Li, Guangxin, Wang, Zheng, Dahlman, James E, Malagon-Lopez, Jose, Gujja, Sharvari, Cilfone, Nicholas A, Kauffman, Kevin J, Sun, Lele, Sun, Hongye, Zhang, Xinbo, Aryal, Binod, Canfran-Duque, Alberto, Liu, Rebecca, Kusters, Pascal, Sehgal, Alfica, Jiao, Yang, Anderson, Daniel G, Gulcher, Jeffrey, Fernandez-Hernando, Carlos, Lutgens, Esther, Schwartz, Martin A, Pober, Jordan S, Chittenden, Thomas W, Tellides, George, Simons, Michael
Published in Nature metabolism (01.09.2019)
Published in Nature metabolism (01.09.2019)
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Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor
Farutin, Victor, Prod'homme, Thomas, McConnell, Kevin, Washburn, Nathaniel, Halvey, Patrick, Etzel, Carol J, Guess, Jamey, Duffner, Jay, Getchell, Kristen, Meccariello, Robin, Gutierrez, Bryan, Honan, Christopher, Zhao, Ganlin, Cilfone, Nicholas A, Gunay, Nur Sibel, Hillson, Jan L, DeLuca, David S, Saunders, Katherine C, Pappas, Dimitrios A, Greenberg, Jeffrey D, Kremer, Joel M, Manning, Anthony M, Ling, Leona E, Capila, Ishan
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Published in Arthritis research & therapy (23.10.2019)
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Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity-mediated antimicrobial responses with caseation during mycobacterium tuberculosis infection
Cilfone, Nicholas A, Ford, Christopher B, Marino, Simeone, Mattila, Joshua T, Gideon, Hannah P, Flynn, JoAnne L, Kirschner, Denise E, Linderman, Jennifer J
Published in The Journal of immunology (1950) (15.01.2015)
Published in The Journal of immunology (1950) (15.01.2015)
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A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment
Pienaar, Elsje, Cilfone, Nicholas A, Lin, Philana Ling, Dartois, Véronique, Mattila, Joshua T, Butler, J Russell, Flynn, JoAnne L, Kirschner, Denise E, Linderman, Jennifer J
Published in Journal of theoretical biology (21.02.2015)
Published in Journal of theoretical biology (21.02.2015)
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A multi-scale approach to designing therapeutics for tuberculosis
Linderman, Jennifer J, Cilfone, Nicholas A, Pienaar, Elsje, Gong, Chang, Kirschner, Denise E
Published in Integrative biology (Cambridge) (11.05.2015)
Published in Integrative biology (Cambridge) (11.05.2015)
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Journal Article
Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology
Cicchese, Joseph M., Evans, Stephanie, Hult, Caitlin, Joslyn, Louis R., Wessler, Timothy, Millar, Jess A., Marino, Simeone, Cilfone, Nicholas A., Mattila, Joshua T., Linderman, Jennifer J., Kirschner, Denise E.
Published in Immunological reviews (11.08.2018)
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Published in Immunological reviews (11.08.2018)
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Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection (IRC5P.475)
Marino, Simeone, Cilfone, Nicholas, Mattila, Joshua, Flynn, JoAnne, Linderman, Jennifer, Kirschner, Denise
Published in The Journal of immunology (1950) (01.05.2014)
Published in The Journal of immunology (1950) (01.05.2014)
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