A small molecule inhibitor of the chloride channel TMEM16A blocks vascular smooth muscle contraction and lowers blood pressure in spontaneously hypertensive rats
Cil, Onur, Chen, Xiaolan, Askew Page, Henry R., Baldwin, Samuel N., Jordan, Maria C., Myat Thwe, Pyone, Anderson, Marc O., Haggie, Peter M., Greenwood, Iain A., Roos, Kenneth P., Verkman, Alan S.
Published in Kidney international (01.08.2021)
Published in Kidney international (01.08.2021)
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Journal Article
Structure of human NCC: insights into the inhibition mechanism of thiazides
de Souza Goncalves, Livia, Yottasan, Pattareeya, Cil, Onur
Published in Signal transduction and targeted therapy (03.07.2023)
Published in Signal transduction and targeted therapy (03.07.2023)
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Journal Article
Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins
Cil, Onur, Phuan, Puay-Wah, Gillespie, Anne Marie, Lee, Sujin, Tradtrantip, Lukmanee, Yin, Jianyi, Tse, Ming, Zachos, Nicholas C, Lin, Ruxian, Donowitz, Mark, Verkman, Alan S
Published in The FASEB journal (01.02.2017)
Published in The FASEB journal (01.02.2017)
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Journal Article
Slowed gastric emptying and improved oral glucose tolerance produced by a nanomolar-potency inhibitor of calcium-activated chloride channel TMEM16A
Cil, Onur, Anderson, Marc O, Yen, Robert, Kelleher, Bryan, Huynh, Tony L, Seo, Youngho, Nilsen, Steven P, Turner, Jerrold R, Verkman, Alan S
Published in The FASEB journal (01.10.2019)
Published in The FASEB journal (01.10.2019)
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Journal Article
Family History of Renal Disease Severity Predicts the Mutated Gene in ADPKD
BARUA, Moumita, CIL, Onur, PATERSON, Andrew D, WANG, Kairon, NING HE, DICKS, Elizabeth, PARFREY, Patrick, PEI, York
Published in Journal of the American Society of Nephrology (01.08.2009)
Published in Journal of the American Society of Nephrology (01.08.2009)
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Journal Article
Intestinal epithelial potassium channels and CFTR chloride channels activated in ErbB tyrosine kinase inhibitor diarrhea
Duan, Tianying, Cil, Onur, Thiagarajah, Jay R, Verkman, Alan S
Published in JCI insight (21.02.2019)
Published in JCI insight (21.02.2019)
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Journal Article
Substituted 2-Acylaminocycloalkylthiophene-3-carboxylic Acid Arylamides as Inhibitors of the Calcium-Activated Chloride Channel Transmembrane Protein 16A (TMEM16A)
Truong, Eric C., Phuan, Puay W., Reggi, Amanda L., Ferrera, Loretta, Galietta, Luis J. V., Levy, Sarah E., Moises, Alannah C., Cil, Onur, Diez-Cecilia, Elena, Lee, Sujin, Verlanan, Alan S., Anderson, Marc O.
Published in Journal of medicinal chemistry (08.06.2017)
Published in Journal of medicinal chemistry (08.06.2017)
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Journal Article
Small-molecule inhibitor of intestinal anion exchanger SLC26A3 for treatment of hyperoxaluria and nephrolithiasis
Cil, Onur, Chu, Tifany, Lee, Sujin, Haggie, Peter M., Verkman, Alan S.
Published in JCI insight (08.07.2022)
Published in JCI insight (08.07.2022)
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Journal Article
Repurposing calcium-sensing receptor agonist cinacalcet for treatment of CFTR-mediated secretory diarrheas
Oak, Apurva A, Chhetri, Parth D, Rivera, Amber A, Verkman, Alan S, Cil, Onur
Published in JCI insight (22.02.2021)
Published in JCI insight (22.02.2021)
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Journal Article
A Turkish BCS1L mutation causes GRACILE-like disorder
Serdaroğlu, Esra, Takcı, Şahin, Kotarsky, Heike, Çil, Onur, Utine, Eda, Yiğit, Şule, Fellman, Vineta
Published in Turkish journal of pediatrics (2017)
Published in Turkish journal of pediatrics (2017)
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Journal Article
A novel mutation in protein C gene (PROC) causing severe phenotype in neonatal period
Unal, Sule, Gumruk, Fatma, Yigit, Sule, Tuncer, Murat, Tavil, Betul, Cil, Onur, Takci, Sahin, Urata, Michiyo, Hotta, Taeko, Kang, Dongchon, Cetin, Mualla
Published in Pediatric blood & cancer (01.04.2014)
Published in Pediatric blood & cancer (01.04.2014)
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Journal Article
Evidence for Pathogenicity of Atypical Splice Mutations in Autosomal Dominant Polycystic Kidney Disease
Wang, Kiarong, Zhao, Xiao, Chan, Shelly, Cil, Onur, He, Ning, Song, Xuewen, Paterson, Andrew D, Pei, York
Published in Clinical journal of the American Society of Nephrology (01.02.2009)
Published in Clinical journal of the American Society of Nephrology (01.02.2009)
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Journal Article
278 ZINC INHIBITS CYCLIC AMP AGONISTS-INDUCED CHLORIDE SECRETION IN HUMAN INTESTINAL EPITHELIAL CELLS AND MOUSE INTESTINE VIA CALCIUM-SENSING RECEPTOR ACTIVATION
Yottasan, Pattareeya, Chu, Qi Tifany, Cil, Onur
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2023)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2023)
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Journal Article