Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
Krönke, Jan, Udeshi, Namrata D., Narla, Anupama, Grauman, Peter, Hurst, Slater N., McConkey, Marie, Svinkina, Tanya, Heckl, Dirk, Comer, Eamon, Li, Xiaoyu, Ciarlo, Christie, Hartman, Emily, Munshi, Nikhil, Schenone, Monica, Schreiber, Stuart L., Carr, Steven A., Ebert, Benjamin L
Published in Science (American Association for the Advancement of Science) (17.01.2014)
Published in Science (American Association for the Advancement of Science) (17.01.2014)
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De novo design of protein logic gates
Chen, Zibo, Kibler, Ryan D, Hunt, Andrew, Busch, Florian, Pearl, Jocelynn, Jia, Mengxuan, VanAernum, Zachary L, Wicky, Basile I M, Dods, Galen, Liao, Hanna, Wilken, Matthew S, Ciarlo, Christie, Green, Shon, El-Samad, Hana, Stamatoyannopoulos, John, Wysocki, Vicki H, Jewett, Michael C, Boyken, Scott E, Baker, David
Published in Science (American Association for the Advancement of Science) (03.04.2020)
Published in Science (American Association for the Advancement of Science) (03.04.2020)
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A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation
Kaufman, Charles K., Mosimann, Christian, Fan, Zi Peng, Yang, Song, Thomas, Andrew J., Ablain, Julien, Tan, Justin L., Fogley, Rachel D., van Rooijen, Ellen, Hagedorn, Elliott J., Ciarlo, Christie, White, Richard M., Matos, Dominick A., Puller, Ann-Christin, Santoriello, Cristina, Liao, Eric C., Young, Richard A., Zon, Leonard I.
Published in Science (American Association for the Advancement of Science) (29.01.2016)
Published in Science (American Association for the Advancement of Science) (29.01.2016)
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A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development
Ciarlo, Christie, Kaufman, Charles K, Kinikoglu, Beste, Michael, Jonathan, Yang, Song, D Amato, Christopher, Blokzijl-Franke, Sasja, den Hertog, Jeroen, Schlaeger, Thorsten M, Zhou, Yi, Liao, Eric, Zon, Leonard I
Published in eLife (23.08.2017)
Published in eLife (23.08.2017)
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CD4-Targeted Fusosomes Are Capable of Transducing Resting T Helper Cells to Generate Highly Potent CAR-T Cells
Ciarlo, Christie, Frye, Zach, DeGroot, Andre, Flores, Walter, Elpek, Kutlu, Pepper, Lauren, Johnson, Adam, Shah, Jagesh V, Foster, Aaron E., Fry, Terry J.
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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A Zebrafish Embryo Culture System Defines Factors that Promote Vertebrate Myogenesis across Species
Xu, Cong, Tabebordbar, Mohammadsharif, Iovino, Salvatore, Ciarlo, Christie, Liu, Jingxia, Castiglioni, Alessandra, Price, Emily, Liu, Min, Barton, Elisabeth R., Kahn, C. Ronald, Wagers, Amy J., Zon, Leonard I.
Published in Cell (07.11.2013)
Published in Cell (07.11.2013)
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Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
Mortison, Jonathan D., Schenone, Monica, Myers, Jacob A., Zhang, Ziyang, Chen, Linfeng, Ciarlo, Christie, Comer, Eamon, Natchiar, S. Kundhavai, Carr, Steven A., Klaholz, Bruno P., Myers, Andrew G.
Published in Cell chemical biology (20.12.2018)
Published in Cell chemical biology (20.12.2018)
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Abstract 2735: Development of a novel, fully human anti-CD19 chimeric antigen receptor for in vivo delivery via CD8-targeted fusosome
Kinder, Jeremy M., Ciarlo, Christie, Estrada, Chanel Athena, van Hoeven, Neal, Chaturvedi, Vandana, Zipp, Garrett, Lampano, Aaron, Johnson, Adam J., Elpek, Kutlu, Fry, Terry J., Foster, Aaron E.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract PR06: The reemergence of neural crest progenitor identity is a key event in the initiation of melanoma from a field of cancer-prone melanocytes
Kaufman, Charles K., Mosimann, Christian, Thomas, Andrew, Fan, Zi Peng, Yang, Song, Tan, Justin, Fogley, Rachel D., Rooijen, Ellen van, Hagedorn, Elliott, Ciarlo, Christie, White, Richard, Matos, Dominick, Puller, Ann-Christin, Santoriello, Cristina, Liao, Eric, Young, Richard A., Zon, Leonard I.
Published in Molecular cancer research (01.04.2016)
Published in Molecular cancer research (01.04.2016)
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Journal Article
Lenalidomide Promotes CRBN-Mediated Ubiquitination and Degradation of IKZF1 and IKZF3
Krönke, Jan, Udeshi, Namrata, Narla, Anupama, Grauman, Peter, Hurst, Slater, McConkey, Marie, Svinkina, Tanya, Heckl, Dirk, Comer, Eamon, Li, Xiaoyu, Ciarlo, Christie, Hartman, Emily, Schenone, Monica, Schreiber, Stuart, Carr, Steven A., Ebert, Benjamin L.
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Inhibition of the CRBN-DDB1-CUL4-ROC1 E3 Ubiquitin Ligase Mediates the Anti-Proliferative and Immunomodulatory Properties of Lenalidomide
Krönke, Jan, Narla, Anupama, Hurst, Slater N., Udeshi, Namrata, Schenone, Monica, McConkey, Marie, Grauman, Peter, Heckl, Dirk, McAuley, Randall, Ciarlo, Christie, Comer, Eamon, Li, Xiaoyu, Carr, Steven A., Ebert, Benjamin L.
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling
Chou, Danny Hung-Chieh, Vetere, Amedeo, Choudhary, Amit, Scully, Stephen S, Schenone, Monica, Tang, Alicia, Gomez, Rachel, Burns, Sean M, Lundh, Morten, Vital, Tamara, Comer, Eamon, Faloon, Patrick W, Dančík, Vlado, Ciarlo, Christie, Paulk, Joshiawa, Dai, Mingji, Reddy, Clark, Sun, Hanshi, Young, Matthew, Donato, Nicholas, Jaffe, Jacob, Clemons, Paul A, Palmer, Michelle, Carr, Steven A, Schreiber, Stuart L, Wagner, Bridget K
Published in Journal of the American Chemical Society (24.06.2015)
Published in Journal of the American Chemical Society (24.06.2015)
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COMPOSITIONS AND METHODS FOR MODULATION OF GENE EXPRESSION
PEARL, Joycelynn, CIARLO, Christie, GREEN, Shon, WILKEN, Matthew, URNOV, Fyodor, STAMATOYANNOPOULOS, John A
Year of Publication 13.09.2023
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Year of Publication 13.09.2023
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CD4-SPECIFIC ANTIBODY CONSTRUCTS AND COMPOSITIONS AND USES THEREOF
SHAH, Jagesh Vigaykumar, MACKENZIE, Lauren Pepper, CIARLO, Christie, CRUITE, Patricia Ann, FRYE, Zachary P, VAN HOEVEN, Neal, FLORES, Walter, TRUDEAU, Kyle Marvin, DEGROOT, Andre, JOHNSON, Adam
Year of Publication 17.10.2024
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Year of Publication 17.10.2024
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USE OF CD4-TARGETED VIRAL VECTORS
ELPEK, Kutlu, MACKENZIE, Lauren Pepper, CIARLO, Christie, BANDORO, Christopher, MATIAS, Albert Ruzo, SHAH, Jagesh Vijaykumar, ENNAJDAOUI, Hanane, FRYE, Zach, JOHNSON, Adam, FOSTER, Aaron
Year of Publication 17.10.2024
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Year of Publication 17.10.2024
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Compositions and Methods for Modulation of Gene Expression
Ciarlo, Christie, Stamatoyannopoulos, John A, Pearl, Joycelynn, Urnov, Fyodor, Wilken, Matthew, Green, Shon
Year of Publication 15.09.2022
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Year of Publication 15.09.2022
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USE OF CD4-TARGETED VIRAL VECTORS
ELPEK, Kutlu, MACKENZIE, Lauren Pepper, CIARLO, Christie, BANDORO, Christopher, MATIAS, Albert Ruzo, SHAH, Jagesh Vijaykumar, ENNAJDAOUI, Hanane, FRYE, Zach, JOHNSON, Adam, FOSTER, Aaron
Year of Publication 12.06.2024
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Year of Publication 12.06.2024
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COMPOSITIONS AND METHODS FOR MODULATION OF GENE EXPRESSION
PEARL, Joycelynn, CIARLO, Christie, GREEN, Shon, WILKEN, Matthew, URNOV, Fyodor, STAMATOYANNOPOULOS, John A
Year of Publication 15.06.2022
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Year of Publication 15.06.2022
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CD4-SPECIFIC ANTIBODY CONSTRUCTS AND COMPOSITIONS AND USES THEREOF
SHAH, Jagesh Vigaykumar, MACKENZIE, Lauren Pepper, CIARLO, Christie, CRUITE, Patricia Ann, FRYE, Zachary P, VAN HOEVEN, Neal, FLORES, Walter, TRUDEAU, Kyle Marvin, DEGROOT, Andre, JOHNSON, Adam
Year of Publication 04.01.2024
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Year of Publication 04.01.2024
Patent