A Programmable Dual-RNA—Guided DNA Endonuclease in Adaptive Bacterial Immunity
Jinek, Martin, Chylinski, Krzysztof, Fonfara, Ines, Hauer, Michael, Doudna, Jennifer A., Charpentier, Emmanuelle
Published in Science (American Association for the Advancement of Science) (17.08.2012)
Published in Science (American Association for the Advancement of Science) (17.08.2012)
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Journal Article
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
Deltcheva, Elitza, Chylinski, Krzysztof, Sharma, Cynthia M., Gonzales, Karine, Chao, Yanjie, Pirzada, Zaid A., Eckert, Maria R., Vogel, Jörg, Charpentier, Emmanuelle
Published in Nature (London) (31.03.2011)
Published in Nature (London) (31.03.2011)
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Journal Article
Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches
Bratovič, Majda, Fonfara, Ines, Chylinski, Krzysztof, Gálvez, Eric J. C., Sullivan, Timothy J., Boerno, Stefan, Timmermann, Bernd, Boettcher, Michael, Charpentier, Emmanuelle
Published in Nature chemical biology (01.05.2020)
Published in Nature chemical biology (01.05.2020)
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Journal Article
CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci
Chylinski, Krzysztof, Hubmann, Maria, Hanna, Ruth E., Yanchus, Connor, Michlits, Georg, Uijttewaal, Esther C. H., Doench, John, Schramek, Daniel, Elling, Ulrich
Published in Nature communications (29.11.2019)
Published in Nature communications (29.11.2019)
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Journal Article
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo
Bestas, Burcu, Wimberger, Sandra, Degtev, Dmitrii, Madsen, Alexandra, Rottner, Antje K., Karlsson, Fredrik, Naumenko, Sergey, Callahan, Megan, Touza, Julia Liz, Francescatto, Margherita, Möller, Carl Ivar, Badertscher, Lukas, Li, Songyuan, Cerboni, Silvia, Selfjord, Niklas, Ericson, Elke, Gordon, Euan, Firth, Mike, Chylinski, Krzysztof, Taheri-Ghahfarokhi, Amir, Bohlooly-Y, Mohammad, Snowden, Mike, Pangalos, Menelaos, Nuttall, Barrett, Akcakaya, Pinar, Sienski, Grzegorz, Maresca, Marcello
Published in Nature communications (06.09.2023)
Published in Nature communications (06.09.2023)
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Journal Article
Classification and evolution of type II CRISPR-Cas systems
Chylinski, Krzysztof, Makarova, Kira S, Charpentier, Emmanuelle, Koonin, Eugene V
Published in Nucleic acids research (02.06.2014)
Published in Nucleic acids research (02.06.2014)
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Journal Article
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
Fonfara, Ines, Le Rhun, Anaïs, Chylinski, Krzysztof, Makarova, Kira S, Lécrivain, Anne-Laure, Bzdrenga, Janek, Koonin, Eugene V, Charpentier, Emmanuelle
Published in Nucleic acids research (01.02.2014)
Published in Nucleic acids research (01.02.2014)
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Journal Article
Zongertinib (BI 1810631), an irreversible HER2 TKI, spares EGFR signaling and improves therapeutic response in preclinical models and patients with HER2-driven cancers
Wilding, Birgit, Woelflingseder, Lydia, Baum, Anke, Chylinski, Krzysztof, Vainorius, Gintautas, Gibson, Neil, Waizenegger, Irene C, Gerlach, Daniel, Augsten, Martin, Spreitzer, Fiona, Shirai, Yukina, Ikegami, Masachika, Tilandyova, Sylvia, Scharn, Dirk, Pearson, Mark A, Popow, Johannes, Obenauf, Anna C, Yamamoto, Noboru, Kondo, Shunsuke, Opdam, Frans L, Bruining, Annemarie, Kohsaka, Shinji, Kraut, Norbert, Heymach, John V, Solca, Flavio, Neumuller, Ralph A
Published in Cancer discovery (09.09.2024)
Published in Cancer discovery (09.09.2024)
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Journal Article
RNA sequencing uncovers antisense RNAs and novel small RNAs in Streptococcus pyogenes
Le Rhun, Anaïs, Beer, Yan Yan, Reimegård, Johan, Chylinski, Krzysztof, Charpentier, Emmanuelle
Published in RNA biology (01.02.2016)
Published in RNA biology (01.02.2016)
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Journal Article
Vapor-liquid equilibrium for phenol + α-methyl benzyl alcohol and 2-ethoxyethanol + n-butyl formate : Project results from the Design Institute for Physical Properties (DIPPR) of the American Institute of Chemical Engineers
CHYLINSKI, Krzysztof, FRAS, Zbigniew, MALANOWSKI, Stanisław K
Published in Journal of chemical and engineering data (2004)
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Published in Journal of chemical and engineering data (2004)
Journal Article
Vapor-liquid equilibrium for propylene glycol + 2-(2-hexyloxyethoxy)ethanol and 1-methyl-2-pyrrolidone + 1-methoxypropan-2-ol : Project results from the Design Institute for Physical Properties (DIPPR) of the American Institute of Chemical Engineers
CHYLINSKI, Krzysztof, FRAS, Zbigniew, MALANOWSKI, Stanislaw K
Published in Journal of chemical and engineering data (2004)
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Published in Journal of chemical and engineering data (2004)
Journal Article