Interpretation of somatic POLE mutations in endometrial carcinoma
León‐Castillo, Alicia, Britton, Heidi, McConechy, Melissa K, McAlpine, Jessica N, Nout, Remi, Kommoss, Stefan, Brucker, Sara Y, Carlson, Joseph W, Epstein, Elisabeth, Rau, Tilman T, Bosse, Tjalling, Church, David N, Gilks, C Blake
Published in The Journal of pathology (01.03.2020)
Published in The Journal of pathology (01.03.2020)
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Deep learning for prediction of colorectal cancer outcome: a discovery and validation study
Skrede, Ole-Johan, De Raedt, Sepp, Kleppe, Andreas, Hveem, Tarjei S, Liestøl, Knut, Maddison, John, Askautrud, Hanne A, Pradhan, Manohar, Nesheim, John Arne, Albregtsen, Fritz, Farstad, Inger Nina, Domingo, Enric, Church, David N, Nesbakken, Arild, Shepherd, Neil A, Tomlinson, Ian, Kerr, Rachel, Novelli, Marco, Kerr, David J, Danielsen, Håvard E
Published in The Lancet (British edition) (01.02.2020)
Published in The Lancet (British edition) (01.02.2020)
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A panoply of errors: polymerase proofreading domain mutations in cancer
Rayner, Emily, van Gool, Inge C., Palles, Claire, Kearsey, Stephen E., Bosse, Tjalling, Tomlinson, Ian, Church, David N.
Published in Nature reviews. Cancer (01.02.2016)
Published in Nature reviews. Cancer (01.02.2016)
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3D Joint Inversion of Scanning Magnetic Microscopy Data
Pastore, Z., Lelievre, P., McEnroe, S. A., Church, N. S.
Published in Geophysical research letters (16.01.2022)
Published in Geophysical research letters (16.01.2022)
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Evaluation of PIK3CA Mutation As a Predictor of Benefit From Nonsteroidal Anti-Inflammatory Drug Therapy in Colorectal Cancer
DOMINGO, Enric, CHURCH, David N, SIEBER, Oliver, RAMAMOORTHY, Rajarajan, YANAGISAWA, Yoko, JOHNSTONE, Elaine, DAVIDSON, Brian, KERR, David J, TOMLINSON, Ian P. M, MIDGLEY, Rachel
Published in Journal of clinical oncology (01.12.2013)
Published in Journal of clinical oncology (01.12.2013)
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POLE Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial Cancer
van Gool, Inge C, Eggink, Florine A, Freeman-Mills, Luke, Stelloo, Ellen, Marchi, Emanuele, de Bruyn, Marco, Palles, Claire, Nout, Remi A, de Kroon, Cor D, Osse, Elisabeth M, Klenerman, Paul, Creutzberg, Carien L, Tomlinson, Ian Pm, Smit, Vincent Thbm, Nijman, Hans W, Bosse, Tjalling, Church, David N
Published in Clinical cancer research (15.07.2015)
Published in Clinical cancer research (15.07.2015)
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Prognostic significance of POLE proofreading mutations in endometrial cancer
Church, David N, Stelloo, Ellen, Nout, Remi A, Valtcheva, Nadejda, Depreeuw, Jeroen, ter Haar, Natalja, Noske, Aurelia, Amant, Frederic, Tomlinson, Ian P M, Wild, Peter J, Lambrechts, Diether, Jürgenliemk-Schulz, Ina M, Jobsen, Jan J, Smit, Vincent T H B M, Creutzberg, Carien L, Bosse, Tjalling
Published in JNCI : Journal of the National Cancer Institute (01.01.2015)
Published in JNCI : Journal of the National Cancer Institute (01.01.2015)
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Tertiary lymphoid structures critical for prognosis in endometrial cancer patients
Horeweg, Nanda, Workel, Hagma H., Loiero, Dominik, Church, David N., Vermij, Lisa, Léon-Castillo, Alicia, Krog, Ricki T., de Boer, Stephanie M., Nout, Remi A., Powell, Melanie E., Mileshkin, Linda R., MacKay, Helen, Leary, Alexandra, Singh, Naveena, Jürgenliemk-Schulz, Ina M., Smit, Vincent T. H. B. M., Creutzberg, Carien L., Koelzer, Viktor H., Nijman, Hans W., Bosse, Tjalling, de Bruyn, Marco
Published in Nature communications (16.03.2022)
Published in Nature communications (16.03.2022)
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On the design of low modulus Ti–Nb–Au alloys for biomedical applications
Church, N.L., Prasad, A., Jones, N.G.
Published in Journal of the mechanical behavior of biomedical materials (01.09.2024)
Published in Journal of the mechanical behavior of biomedical materials (01.09.2024)
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CD103+ tumor-infiltrating lymphocytes are tumor-reactive intraepithelial CD8+ T cells associated with prognostic benefit and therapy response in cervical cancer
Komdeur, Fenne L., Prins, Thalina M., van de Wall, Stephanie, Plat, Annechien, Wisman, G. Bea A., Hollema, Harry, Daemen, Toos, Church, David N., de Bruyn, Marco, Nijman, Hans W.
Published in Oncoimmunology (02.09.2017)
Published in Oncoimmunology (02.09.2017)
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Journal Article
Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response
Temko, Daniel, Van Gool, Inge C, Rayner, Emily, Glaire, Mark, Makino, Seiko, Brown, Matthew, Chegwidden, Laura, Palles, Claire, Depreeuw, Jeroen, Beggs, Andrew, Stathopoulou, Chaido, Mason, John, Baker, Ann‐Marie, Williams, Marc, Cerundolo, Vincenzo, Rei, Margarida, Taylor, Jenny C, Schuh, Anna, Ahmed, Ahmed, Amant, Frédéric, Lambrechts, Diether, Smit, Vincent THBM, Bosse, Tjalling, Graham, Trevor A, Church, David N, Tomlinson, Ian
Published in The Journal of pathology (01.07.2018)
Published in The Journal of pathology (01.07.2018)
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Immunological profiling of molecularly classified high-risk endometrial cancers identifies POLE-mutant and microsatellite unstable carcinomas as candidates for checkpoint inhibition
Eggink, Florine A., Van Gool, Inge C., Leary, Alexandra, Pollock, Pamela M., Crosbie, Emma J., Mileshkin, Linda, Jordanova, Ekaterina S., Adam, Julien, Freeman-Mills, Luke, Church, David N., Creutzberg, Carien L., De Bruyn, Marco, Nijman, Hans W., Bosse, Tjalling
Published in Oncoimmunology (01.02.2017)
Published in Oncoimmunology (01.02.2017)
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Mapping and Modeling Sources of Natural Remanent Magnetization in the Microcline–Sillimanite Gneiss, Northwest Adirondack Mountains: Implications for Crustal Magnetism
Pastore, Z., McEnroe, S. A., Church, N. S., Oda, H.
Published in Geochemistry, geophysics, geosystems : G3 (01.03.2021)
Published in Geochemistry, geophysics, geosystems : G3 (01.03.2021)
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Clinicopathological and molecular characterisation of ‘multiple‐classifier’ endometrial carcinomas
León‐Castillo, Alicia, Gilvazquez, Ester, Nout, Remi, Smit, Vincent THBM, McAlpine, Jessica N, McConechy, Melissa, Kommoss, Stefan, Brucker, Sara Y, Carlson, Joseph W, Epstein, Elisabeth, Rau, Tilman T, Soslow, Robert A, Ganesan, Raji, Matias‐Guiu, Xavier, Oliva, Esther, Harrison, Beth T, Church, David N, Gilks, C Blake, Bosse, Tjalling
Published in The Journal of pathology (01.03.2020)
Published in The Journal of pathology (01.03.2020)
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Journal Article
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study
Domingo, Enric, Freeman-Mills, Luke, Rayner, Emily, Glaire, Mark, Briggs, Sarah, Vermeulen, Louis, Fessler, Evelyn, Medema, Jan Paul, Boot, Arnoud, Morreau, Hans, van Wezel, Tom, Liefers, Gerrit-Jan, Lothe, Ragnhild A, Danielsen, Stine A, Sveen, Anita, Nesbakken, Arild, Zlobec, Inti, Lugli, Alessandro, Koelzer, Viktor H, Berger, Martin D, Castellví-Bel, Sergi, Muñoz, Jenifer, de Bruyn, Marco, Nijman, Hans W, Novelli, Marco, Lawson, Kay, Oukrif, Dahmane, Frangou, Eleni, Dutton, Peter, Tejpar, Sabine, Delorenzi, Mauro, Kerr, Rachel, Kerr, David, Tomlinson, Ian, Church, David N
Published in The lancet. Gastroenterology & hepatology (01.11.2016)
Published in The lancet. Gastroenterology & hepatology (01.11.2016)
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Long‐term hypovitaminosis D and secondary hyperparathyroidism outcomes of the Roux‐en‐Y gastric bypass: a systematic review
Switzer, N. J., Marcil, G., Prasad, S., Debru, E., Church, N., Mitchell, P., Billington, E. O., Gill, R. S.
Published in Obesity reviews (01.05.2017)
Published in Obesity reviews (01.05.2017)
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